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Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations
Zhanel, George G., Lawrence, Courtney K., Adam, Heather, Schweizer, Frank, Zelenitsky, Sheryl, Zhanel, Michael, Lagacé-Wiens, Philippe R. S., Walkty, Andrew, Denisuik, Andrew, Golden, Alyssa, Gin, Alfred S., Hoban, Daryl J., Lynch, Joseph P., Karlowsky, James A.
Published in Drugs (New York, N.Y.) (01.01.2018)
Published in Drugs (New York, N.Y.) (01.01.2018)
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Meropenem-RPX7009 Concentrations in Plasma, Epithelial Lining Fluid, and Alveolar Macrophages of Healthy Adult Subjects
Wenzler, Eric, Gotfried, Mark H., Loutit, Jeffrey S., Durso, Stephanie, Griffith, David C., Dudley, Michael N., Rodvold, Keith A.
Published in Antimicrobial agents and chemotherapy (01.12.2015)
Published in Antimicrobial agents and chemotherapy (01.12.2015)
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Single-Dose Pharmacokinetics and Safety of Meropenem-Vaborbactam in Subjects with Chronic Renal Impairment
Rubino, Christopher M., Bhavnani, Sujata M., Loutit, Jeffery S., Lohse, Brooke, Dudley, Michael N., Griffith, David C.
Published in Antimicrobial agents and chemotherapy (01.03.2018)
Published in Antimicrobial agents and chemotherapy (01.03.2018)
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Population Pharmacokinetics of Meropenem and Vaborbactam Based on Data from Noninfected Subjects and Infected Patients
Trang, M., Griffith, D. C., Bhavnani, S. M., Loutit, J. S., Dudley, M. N., Ambrose, P. G., Rubino, C. M.
Published in Antimicrobial agents and chemotherapy (17.08.2021)
Published in Antimicrobial agents and chemotherapy (17.08.2021)
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Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Vaborbactam and Meropenem Alone and in Combination following Single and Multiple Doses in Healthy Adult Subjects
Rubino, Christopher M., Bhavnani, Sujata M., Loutit, Jeffery S., Morgan, Elizabeth E., White, Dan, Dudley, Michael N., Griffith, David C.
Published in Antimicrobial agents and chemotherapy (01.04.2018)
Published in Antimicrobial agents and chemotherapy (01.04.2018)
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First-in-human study to evaluate the safety, tolerability, and population pharmacokinetic/pharmacodynamic target attainment analysis of FL058 alone and in combination with meropenem in healthy subjects
Huang, Zhiwei, Yang, Xinyi, Jin, Yi, Yu, Jicheng, Cao, Guoying, Wang, Jingjing, Hu, Yingying, Dai, Jingyi, Wu, Jufang, Wei, Qiong, Tian, Yan, Yu, Shuyan, Zhu, Xu, Mao, Xiaomeng, Liu, Wei, Liang, Hong, Zheng, Shansong, Ju, Yunfei, Wang, Zenghua, Zhang, Jing, Wu, Xiaojie
Published in Antimicrobial agents and chemotherapy (10.01.2024)
Published in Antimicrobial agents and chemotherapy (10.01.2024)
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Is Meropenem as a Monotherapy Truly Incompetent for Meropenem-Nonsusceptible Bacterial Strains? A Pharmacokinetic/Pharmacodynamic Modeling With Monte Carlo Simulation
Song, Xiangqing, Wu, Yi, Cao, Lizhi, Yao, Dunwu, Long, Minghui
Published in Frontiers in microbiology (29.11.2019)
Published in Frontiers in microbiology (29.11.2019)
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Meropenem pharmacokinetics in cerebrospinal fluid: comparing intermittent and continuous infusion strategies in critically ill patients—a prospective cohort study
Wicha, Sebastian G., Kinast, Christina, Münchow, Max, Wittova, Sandra, Greppmair, Sebastian, Kunzelmann, Alexandra K., Zoller, Michael, Paal, Michael, Vogeser, Michael, Habler, Katharina, Weig, Thomas, Terpolilli, Nicole, Heck, Suzette, Dimitriadis, Konstantinos, Scharf, Christina, Liebchen, Uwe
Published in Antimicrobial agents and chemotherapy (04.09.2024)
Published in Antimicrobial agents and chemotherapy (04.09.2024)
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Physiologically-based pharmacokinetic/pharmacodynamic modeling of meropenem in critically ill patients
Yang, Yujie, Wang, Yirong, Zeng, Wei, Zhou, Jinhua, Xu, Min, Lan, Ying, Liu, Lvye, Shen, Jian, Zhang, Chuan, He, Qin
Published in Scientific reports (20.08.2024)
Published in Scientific reports (20.08.2024)
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Using machine learning to optimize antibiotic combinations: dosing strategies for meropenem and polymyxin B against carbapenem-resistant Acinetobacter baumannii
Smith, N.M., Lenhard, J.R., Boissonneault, K.R., Landersdorfer, C.B., Bulitta, J.B., Holden, P.N., Forrest, A., Nation, R.L., Li, J., Tsuji, B.T.
Published in Clinical microbiology and infection (01.09.2020)
Published in Clinical microbiology and infection (01.09.2020)
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Dose rationale for the use of meropenem/vaborbactam combination in paediatric patients with Gram‐negative bacterial infections
Fornari, Chiara, Arrieta, Antonio, Bradley, John S., Tout, Mira, Magalhaes, Paulo, Auriol, Faten Koraichi, Borella, Elisa, Piana, Chiara, Della Pasqua, Oscar, Vallespir, Bartomeu Piza, Mazzei, Paolo, Bokesch, Paula M., Hoover, Randall, Capriati, Angela, Habboubi, Nassir
Published in British journal of clinical pharmacology (01.10.2024)
Published in British journal of clinical pharmacology (01.10.2024)
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Population pharmacokinetics of meropenem in critically ill children with different renal functions
Rapp, Mélanie, Urien, Saïk, Foissac, Frantz, Béranger, Agathe, Bouazza, Naïm, Benaboud, Sihem, Bille, Emmanuelle, Zheng, Yi, Gana, Inès, Moulin, Florence, Lesage, Fabrice, Renolleau, Sylvain, Tréluyer, Jean Marc, Hirt, Déborah, Oualha, Mehdi
Published in European journal of clinical pharmacology (01.01.2020)
Published in European journal of clinical pharmacology (01.01.2020)
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Determination of MIC and disk diffusion quality control guidelines for meropenem–vaborbactam, a novel carbapenem/boronic acid β-lactamase inhibitor combination
Munson, Erik, Huband, Michael D., Castanheira, Mariana, Fedler, Kelley A., Flamm, Robert K.
Published in Diagnostic microbiology and infectious disease (01.04.2018)
Published in Diagnostic microbiology and infectious disease (01.04.2018)
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Population pharmacokinetics and probability of target attainment in patients with sepsis under renal replacement therapy receiving continuous infusion of meropenem: Sustained low‐efficiency dialysis and continuous veno‐venous haemodialysis
Westermann, Isabella, Gastine, Silke, Müller, Carsten, Rudolph, Wiebke, Peters, Frank, Bloos, Frank, Pletz, Mathias, Hagel, Stefan
Published in British journal of clinical pharmacology (01.11.2021)
Published in British journal of clinical pharmacology (01.11.2021)
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Cost-effectiveness Comparison of Ceftazidime/Avibactam Versus Meropenem in the Empirical Treatment of Hospital-acquired Pneumonia, Including Ventilator-associated Pneumonia, in Italy
Tichy, Eszter, Torres, Antoni, Bassetti, Matteo, Kongnakorn, Thitima, Di Virgilio, Roberto, Irani, Paurus, Charbonneau, Claudie
Published in Clinical therapeutics (01.05.2020)
Published in Clinical therapeutics (01.05.2020)
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Prediction of Tissue Exposures of Meropenem, Colistin, and Sulbactam in Pediatrics Using Physiologically Based Pharmacokinetic Modeling
Zhu, Shixing, Zhang, Jiayuan, Lv, Zhihua, Zhu, Peijuan, Oo, Charles, Yu, Mingming, Sy, Sherwin K. B.
Published in Clinical pharmacokinetics (01.10.2022)
Published in Clinical pharmacokinetics (01.10.2022)
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A randomised, double-blind, phase 3 study comparing the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem for complicated intra-abdominal infections in hospitalised adults in Asia
Qin, Xinyu, Tran, Binh Giang, Kim, Min Ja, Wang, Lie, Nguyen, Dung Anh, Chen, Qian, Song, Jie, Laud, Peter J., Stone, Gregory G., Chow, Joseph W.
Published in International journal of antimicrobial agents (01.05.2017)
Published in International journal of antimicrobial agents (01.05.2017)
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