Serotonin stimulates secretion of exosomes from microglia cells
Glebov, Konstantin, Löchner, Marie, Jabs, Ronald, Lau, Thorsten, Merkel, Olaf, Schloss, Patrick, Steinhäuser, Christian, Walter, Jochen
Published in Glia (01.04.2015)
Published in Glia (01.04.2015)
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Journal Article
Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia
Herling, Carmen D., Abedpour, Nima, Weiss, Jonathan, Schmitt, Anna, Jachimowicz, Ron Daniel, Merkel, Olaf, Cartolano, Maria, Oberbeck, Sebastian, Mayer, Petra, Berg, Valeska, Thomalla, Daniel, Kutsch, Nadine, Stiefelhagen, Marius, Cramer, Paula, Wendtner, Clemens-Martin, Persigehl, Thorsten, Saleh, Andreas, Altmüller, Janine, Nürnberg, Peter, Pallasch, Christian, Achter, Viktor, Lang, Ulrich, Eichhorst, Barbara, Castiglione, Roberta, Schäfer, Stephan C., Büttner, Reinhard, Kreuzer, Karl-Anton, Reinhardt, Hans Christian, Hallek, Michael, Frenzel, Lukas P., Peifer, Martin
Published in Nature communications (20.02.2018)
Published in Nature communications (20.02.2018)
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Journal Article
The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas
Garces de Los Fayos Alonso, Ines, Liang, Huan-Chang, Turner, Suzanne D, Lagger, Sabine, Merkel, Olaf, Kenner, Lukas
Published in Cancers (28.03.2018)
Published in Cancers (28.03.2018)
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Journal Article
STAT3 and TP53 mutations associate with poor prognosis in anaplastic large cell lymphoma
Lobello, Cosimo, Tichy, Boris, Bystry, Vojtech, Radova, Lenka, Filip, Daniel, Mraz, Marek, Montes-Mojarro, Ivonne-Aidee, Prokoph, Nina, Larose, Hugo, Liang, Huan-Chang, Sharma, Geeta G., Mologni, Luca, Belada, David, Kamaradova, Katerina, Fend, Falko, Gambacorti-Passerini, Carlo, Merkel, Olaf, Turner, Suzanne D., Janikova, Andrea, Pospisilova, Sarka
Published in Leukemia (01.05.2021)
Published in Leukemia (01.05.2021)
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Journal Article
The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma
Schleussner, Nikolai, Merkel, Olaf, Costanza, Mariantonia, Liang, Huan-Chang, Hummel, Franziska, Romagnani, Chiara, Durek, Pawel, Anagnostopoulos, Ioannis, Hummel, Michael, Jöhrens, Korinna, Niedobitek, Antonia, Griffin, Patrick R., Piva, Roberto, Sczakiel, Henrike L., Woessmann, Wilhelm, Damm-Welk, Christine, Hinze, Christian, Stoiber, Dagmar, Gillissen, Bernd, Turner, Suzanne D., Kaergel, Eva, von Hoff, Linda, Grau, Michael, Lenz, Georg, Dörken, Bernd, Scheidereit, Claus, Kenner, Lukas, Janz, Martin, Mathas, Stephan
Published in Leukemia (01.09.2018)
Published in Leukemia (01.09.2018)
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Journal Article
Super-enhancer-based identification of a BATF3/IL-2R−module reveals vulnerabilities in anaplastic large cell lymphoma
Liang, Huan-Chang, Costanza, Mariantonia, Prutsch, Nicole, Zimmerman, Mark W., Gurnhofer, Elisabeth, Montes-Mojarro, Ivonne A., Abraham, Brian J., Prokoph, Nina, Stoiber, Stefan, Tangermann, Simone, Lobello, Cosimo, Oppelt, Jan, Anagnostopoulos, Ioannis, Hielscher, Thomas, Pervez, Shahid, Klapper, Wolfram, Zammarchi, Francesca, Silva, Daniel-Adriano, Garcia, K. Christopher, Baker, David, Janz, Martin, Schleussner, Nikolai, Fend, Falko, Pospíšilová, Šárka, Janiková, Andrea, Wallwitz, Jacqueline, Stoiber, Dagmar, Simonitsch-Klupp, Ingrid, Cerroni, Lorenzo, Pileri, Stefano, de Leval, Laurence, Sibon, David, Fataccioli, Virginie, Gaulard, Philippe, Assaf, Chalid, Knörr, Fabian, Damm-Welk, Christine, Woessmann, Wilhelm, Turner, Suzanne D., Look, A. Thomas, Mathas, Stephan, Kenner, Lukas, Merkel, Olaf
Published in Nature communications (22.09.2021)
Published in Nature communications (22.09.2021)
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Journal Article
Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma
Prutsch, Nicole, Gurnhofer, Elisabeth, Suske, Tobias, Liang, Huan Chang, Schlederer, Michaela, Roos, Simone, Wu, Lawren C., Simonitsch-Klupp, Ingrid, Alvarez-Hernandez, Andrea, Kornauth, Christoph, Leone, Dario A., Svinka, Jasmin, Eferl, Robert, Limberger, Tanja, Aufinger, Astrid, Shirsath, Nitesh, Wolf, Peter, Hielscher, Thomas, Sternberg, Christina, Aberger, Fritz, Schmoellerl, Johannes, Stoiber, Dagmar, Strobl, Birgit, Jäger, Ulrich, Staber, Philipp B., Grebien, Florian, Moriggl, Richard, Müller, Mathias, Inghirami, Giorgio G., Sanda, Takaomi, Look, A. Thomas, Turner, Suzanne D., Kenner, Lukas, Merkel, Olaf
Published in Leukemia (01.03.2019)
Published in Leukemia (01.03.2019)
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Journal Article
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma
Weilemann, Andre, Grau, Michael, Erdmann, Tabea, Merkel, Olaf, Sobhiafshar, Ulduz, Anagnostopoulos, Ioannis, Hummel, Michael, Siegert, Antje, Hayford, Claudia, Madle, Hannelore, Wollert-Wulf, Brigitte, Fichtner, Iduna, Dörken, Bernd, Dirnhofer, Stephan, Mathas, Stephan, Janz, Martin, Emre, N. C. Tolga, Rosenwald, Andreas, Ott, German, Lenz, Peter, Tzankov, Alexandar, Lenz, Georg
Published in Blood (01.01.2015)
Published in Blood (01.01.2015)
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Journal Article
Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma
Pucci, Perla, Lee, Liam C., Han, Miaojun, Matthews, Jamie D., Jahangiri, Leila, Schlederer, Michaela, Manners, Eleanor, Sorby-Adams, Annabel, Kaggie, Joshua, Trigg, Ricky M., Steel, Christopher, Hare, Lucy, James, Emily R., Prokoph, Nina, Ducray, Stephen P., Merkel, Olaf, Rifatbegovic, Firkret, Luo, Ji, Taschner-Mandl, Sabine, Kenner, Lukas, Burke, G. A. Amos, Turner, Suzanne D.
Published in Nature communications (23.04.2024)
Published in Nature communications (23.04.2024)
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Journal Article
The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status
Trigg, Ricky M., Lee, Liam C., Prokoph, Nina, Jahangiri, Leila, Reynolds, C. Patrick, Amos Burke, G. A., Probst, Nicola A., Han, Miaojun, Matthews, Jamie D., Lim, Hong Kai, Manners, Eleanor, Martinez, Sonia, Pastor, Joaquin, Blanco-Aparicio, Carmen, Merkel, Olaf, de los Fayos Alonso, Ines Garces, Kodajova, Petra, Tangermann, Simone, Högler, Sandra, Luo, Ji, Kenner, Lukas, Turner, Suzanne D.
Published in Nature communications (28.11.2019)
Published in Nature communications (28.11.2019)
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Journal Article
Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress
Malcolm, Tim I. M., Villarese, Patrick, Fairbairn, Camilla J., Lamant, Laurence, Trinquand, Amélie, Hook, C. Elizabeth, Burke, G. A. Amos, Brugières, Laurence, Hughes, Katherine, Payet, Dominique, Merkel, Olaf, Schiefer, Ana-Iris, Ashankyty, Ibraheem, Mian, Shahid, Wasik, Mariusz, Turner, Martin, Kenner, Lukas, Asnafi, Vahid, Macintyre, Elizabeth, Turner, Suzanne D.
Published in Nature communications (12.01.2016)
Published in Nature communications (12.01.2016)
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Journal Article
Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling
Hassler, Melanie R., Pulverer, Walter, Lakshminarasimhan, Ranjani, Redl, Elisa, Hacker, Julia, Garland, Gavin D., Merkel, Olaf, Schiefer, Ana-Iris, Simonitsch-Klupp, Ingrid, Kenner, Lukas, Weisenberger, Daniel J., Weinhaeusel, Andreas, Turner, Suzanne D., Egger, Gerda
Published in Cell reports (Cambridge) (04.10.2016)
Published in Cell reports (Cambridge) (04.10.2016)
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Journal Article
JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression
Redmer, Torben, Raigel, Martin, Sternberg, Christina, Ziegler, Roman, Probst, Clara, Lindner, Desiree, Aufinger, Astrid, Limberger, Tanja, Trachtova, Karolina, Kodajova, Petra, Högler, Sandra, Schlederer, Michaela, Stoiber, Stefan, Oberhuber, Monika, Bolis, Marco, Neubauer, Heidi A, Miranda, Sara, Tomberger, Martina, Harbusch, Nora S, Garces de Los Fayos Alonso, Ines, Sternberg, Felix, Moriggl, Richard, Theurillat, Jean-Philippe, Tichy, Boris, Bystry, Vojtech, Persson, Jenny L, Mathas, Stephan, Aberger, Fritz, Strobl, Birgit, Pospisilova, Sarka, Merkel, Olaf, Egger, Gerda, Lagger, Sabine, Kenner, Lukas
Published in Molecular cancer (29.05.2024)
Published in Molecular cancer (29.05.2024)
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Journal Article
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)⁺ and ALK⁻ anaplastic large-cell lymphoma
Merkel, Olaf, Hamacher, Frank, Laimer, Daniela, Sifft, Eveline, Trajanoski, Zlatko, Scheideler, Marcel, Egger, Gerda, Hassler, Melanie R, Thallinger, Christiane, Schmatz, Ana, Turner, Suzanne D, Greil, Richard, Kenner, Lukas
Published in Proceedings of the National Academy of Sciences - PNAS (14.09.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (14.09.2010)
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Journal Article
Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T‐cell lymphoma
Sorger, Helena, Dey, Saptaswa, Vieyra‐Garcia, Pablo Augusto, Pölöske, Daniel, Teufelberger, Andrea R, de Araujo, Elvin D, Sedighi, Abootaleb, Graf, Ricarda, Spiegl, Benjamin, Lazzeri, Isaac, Braun, Till, Garces de los Fayos Alonso, Ines, Schlederer, Michaela, Timelthaler, Gerald, Kodajova, Petra, Pirker, Christine, Surbek, Marta, Machtinger, Michael, Graier, Thomas, Perchthaler, Isabella, Pan, Yi, Fink‐Puches, Regina, Cerroni, Lorenzo, Ober, Jennifer, Otte, Moritz, Albrecht, Jana D, Tin, Gary, Abdeldayem, Ayah, Manaswiyoungkul, Pimyupa, Olaoye, Olasunkanmi O, Metzelder, Martin L, Orlova, Anna, Berger, Walter, Wobser, Marion, Nicolay, Jan P, André, Fiona, Nguyen, Van Anh, Neubauer, Heidi A, Fleck, Roman, Merkel, Olaf, Herling, Marco, Heitzer, Ellen, Gunning, Patrick T, Kenner, Lukas, Moriggl, Richard, Wolf, Peter
Published in EMBO molecular medicine (07.12.2022)
Published in EMBO molecular medicine (07.12.2022)
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Journal Article
Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma
Prutsch, Nicole, Gurnhofer, Elisabeth, Suske, Tobias, Liang, Huan Chang, Schlederer, Michaela, Roos, Simone, Wu, Lawren C., Simonitsch-Klupp, Ingrid, Alvarez-Hernandez, Andrea, Kornauth, Christoph, Leone, Dario A., Svinka, Jasmin, Eferl, Robert, Limberger, Tanja, Aufinger, Astrid, Shirsath, Nitesh, Wolf, Peter, Hielscher, Thomas, Sternberg, Christina, Aberger, Fritz, Schmoellerl, Johannes, Stoiber, Dagmar, Strobl, Birgit, Jäger, Ulrich, Staber, Philipp B., Grebien, Florian, Moriggl, Richard, Müller, Mathias, Inghirami, Giorgio G., Sanda, Takaomi, Look, A. Thomas, Turner, Suzanne D., Kenner, Lukas, Merkel, Olaf
Published in Leukemia (01.11.2020)
Published in Leukemia (01.11.2020)
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Journal Article
Mitochondrial Phosphate–Carrier Deficiency: A Novel Disorder of Oxidative Phosphorylation
Mayr, Johannes A., Merkel, Olaf, Kohlwein, Sepp D., Gebhardt, Boris R., Böhles, Hansjosef, Fötschl, Ulrike, Koch, Johannes, Jaksch, Michaela, Lochmüller, Hanns, Horváth, Rita, Freisinger, Peter, Sperl, Wolfgang
Published in American journal of human genetics (01.03.2007)
Published in American journal of human genetics (01.03.2007)
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Journal Article
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia
Merkel, Olaf, Asslaber, Daniela, Pinon, Josefina, Egle, Alexander, Greil, Richard
Published in Cell cycle (Georgetown, Tex.) (15.07.2010)
Published in Cell cycle (Georgetown, Tex.) (15.07.2010)
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Journal Article
Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target
Jöhrer, Karin, Obkircher, Marlene, Neureiter, Daniel, Parteli, Johanna, Zelle-Rieser, Claudia, Maizner, Eva, Kern, Johann, Hermann, Martin, Hamacher, Frank, Merkel, Olaf, Wacht, Nathalie, Zidorn, Christian, Scheideler, Marcel, Greil, Richard
Published in Journal of molecular medicine (Berlin, Germany) (01.06.2012)
Published in Journal of molecular medicine (Berlin, Germany) (01.06.2012)
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