Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer
van der Noll, Ruud, Marchetti, Serena, Steeghs, Neeltje, Beijnen, Jos H, Mergui-Roelvink, Marja W J, Harms, Emmy, Rehorst, Harriet, Sonke, Gabe S, Schellens, Jan H M
Published in British journal of cancer (28.07.2015)
Published in British journal of cancer (28.07.2015)
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Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1)
van der Noll, Ruud, Jager, Agnes, Ang, Joo Ern, Marchetti, Serena, Mergui-Roelvink, Marja W. J., Lolkema, Martijn P., de Jonge, Maja J. A., van der Biessen, Diane A., Brunetto, Andre T., Arkenau, Hendrik-Tobias, Tchakov, Ilian, Beijnen, Jos H., de Bono, Johann S., Schellens, Jan H. M.
Published in Investigational new drugs (01.08.2020)
Published in Investigational new drugs (01.08.2020)
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Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2)
van der Noll, Ruud, Jager, Agnes, Ang, Joo Ern, Marchetti, Serena, Mergui-Roelvink, Marja W. J., de Bono, Johann S., Lolkema, Martijn P., de Jonge, Maja J. A., van der Biessen, Diane A., Brunetto, Andre T., Arkenau, Hendrik-Tobias, Tchakov, Ilian, Beijnen, Jos H., De Grève, Jacques, Schellens, Jan H. M.
Published in Investigational new drugs (01.08.2020)
Published in Investigational new drugs (01.08.2020)
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A Phase 1 Dose‐Escalation Study of Low‐Dose Metronomic Treatment With Novel Oral Paclitaxel Formulations in Combination With Ritonavir in Patients With Advanced Solid Tumors
Weger, Vincent A., Vermunt, Marit A.C., Stuurman, Frederik E., Burylo, Artur M., Damoiseaux, David, Hendrikx, Jeroen J.M.A., Sawicki, Emilia, Moes, Johannes J., Huitema, Alwin D.R., Nuijen, Bastiaan, Rosing, Hilde, Mergui‐Roelvink, Marja, Beijnen, Jos H., Marchetti, Serena
Published in Clinical pharmacology in drug development (01.06.2021)
Published in Clinical pharmacology in drug development (01.06.2021)
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Poly(ADP)-Ribose Polymerase Inhibition: Frequent Durable Responses in BRCA Carrier Ovarian Cancer Correlating With Platinum-Free Interval
FONG, Peter C, YAP, Timothy A, A'HERN, Roger, TUTT, Andrew, ASHWORTH, Alan, STONE, John, CARMICHAEL, James, SCHELLENS, Jan H. M, DE BONO, Johann S, KAYE, Stan B, BOSS, David S, CARDEN, Craig P, MERGUI-ROELVINK, Marja, GOURLEY, Charlie, DE GREVE, Jacques, LUBINSKI, Jan, SHANLEY, Susan, MESSIOU, Christina
Published in Journal of clinical oncology (20.05.2010)
Published in Journal of clinical oncology (20.05.2010)
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The effect of Echinacea purpurea on the pharmacokinetics of docetaxel
Goey, Andrew K. L., Meijerman, Irma, Rosing, Hilde, Burgers, Jacobus A., Mergui‐Roelvink, Marja, Keessen, Marianne, Marchetti, Serena, Beijnen, Jos H., Schellens, Jan H. M.
Published in British journal of clinical pharmacology (01.09.2013)
Published in British journal of clinical pharmacology (01.09.2013)
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Journal Article
Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function
Devriese, Lot A., Witteveen, Petronella (Els). O., Mergui‐Roelvink, Marja, Smith, Deborah A., Lewis, Lionel D., Mendelson, David S., Bang, Yung‐Jue, Chung, Hyun Choel, Dar, Mohammed M., Huitema, Alwin D. R., Beijnen, Jos H., Voest, Emile E., Schellens, Jan H. M.
Published in British journal of clinical pharmacology (01.08.2015)
Published in British journal of clinical pharmacology (01.08.2015)
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Journal Article
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
Fong, Peter C, Boss, David S, Yap, Timothy A, Tutt, Andrew, Wu, Peijun, Mergui-Roelvink, Marja, Mortimer, Peter, Swaisland, Helen, Lau, Alan, O'Connor, Mark J, Ashworth, Alan, Carmichael, James, Kaye, Stan B, Schellens, Jan H.M, de Bono, Johann S
Published in The New England journal of medicine (09.07.2009)
Published in The New England journal of medicine (09.07.2009)
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Journal Article
Pharmacokinetics and excretion of (14)C-lenvatinib in patients with advanced solid tumors or lymphomas
Dubbelman, Anne-Charlotte, Rosing, Hilde, Nijenhuis, Cynthia, Huitema, Alwin D R, Mergui-Roelvink, Marja, Gupta, Anubha, Verbel, David, Thompson, Gary, Shumaker, Robert, Schellens, Jan H M, Beijnen, Jos H
Published in Investigational new drugs (01.02.2015)
Published in Investigational new drugs (01.02.2015)
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A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir
de Weger, Vincent A, Stuurman, Frederik E, Koolen, Stijn L W, Moes, Johannes J, Hendrikx, Jeroen J M A, Sawicki, Emilia, Thijssen, Bas, Keessen, Marianne, Rosing, Hilde, Mergui-Roelvink, Marja, Huitema, Alwin D R, Nuijen, Bastiaan, Beijnen, Jos H, Schellens, Jan H M, Marchetti, Serena
Published in Clinical cancer research (15.09.2019)
Published in Clinical cancer research (15.09.2019)
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A dose-escalation study of bi-daily once weekly oral docetaxel either as ModraDoc001 or ModraDoc006 combined with ritonavir
de Weger, Vincent A., Stuurman, Frederik E., Hendrikx, Jeroen J.M.A., Moes, Johannes J., Sawicki, Emilia, Huitema, Alwin D.R., Nuijen, Bastiaan, Thijssen, Bas, Rosing, Hilde, Keessen, Marianne, Mergui-Roelvink, Marja, Beijnen, Jos H., Schellens, Jan H.M., Marchetti, Serena
Published in European journal of cancer (1990) (01.11.2017)
Published in European journal of cancer (1990) (01.11.2017)
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Journal Article
The Effect of St John’s Wort on the Pharmacokinetics of Docetaxel
Goey, Andrew K. L., Meijerman, Irma, Rosing, Hilde, Marchetti, Serena, Mergui-Roelvink, Marja, Keessen, Marianne, Burgers, Jacobus A., Beijnen, Jos H., Schellens, Jan H. M.
Published in Clinical pharmacokinetics (2014)
Published in Clinical pharmacokinetics (2014)
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Journal Article
Effects of low-fat and high-fat meals on steady-state pharmacokinetics of lapatinib in patients with advanced solid tumours
Devriese, Lot A., Koch, Kevin M., Mergui-Roelvink, Marja, Matthys, Gemma M., Ma, Wen Wee, Robidoux, Andre, Stephenson, Joe J., Chu, Quincy S. C., Orford, Keith W., Cartee, Leanne, Botbyl, Jeff, Arya, Nikita, Schellens, Jan H. M.
Published in Investigational new drugs (01.06.2014)
Published in Investigational new drugs (01.06.2014)
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Journal Article
Mass balance study of [¹⁴C]eribulin in patients with advanced solid tumors
Dubbelman, Anne-Charlotte, Rosing, Hilde, Jansen, Robert S, Mergui-Roelvink, Marja, Huitema, Alwin D R, Koetz, Barbara, Lymboura, Margarita, Reyderman, Larisa, Lopez-Anaya, Arturo, Schellens, Jan H M, Beijnen, Jos H
Published in Drug metabolism and disposition (01.02.2012)
Published in Drug metabolism and disposition (01.02.2012)
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Journal Article
Pharmacokinetics and excretion of (14)C-omacetaxine in patients with advanced solid tumors
Nijenhuis, Cynthia M, Hellriegel, Edward, Beijnen, Jos H, Hershock, Diane, Huitema, Alwin D R, Lucas, Luc, Mergui-Roelvink, Marja, Munteanu, Mihaela, Rabinovich-Guilatt, Laura, Robertson, Jr, Philmore, Rosing, Hilde, Spiegelstein, Ofer, Schellens, Jan H M
Published in Investigational new drugs (01.10.2016)
Published in Investigational new drugs (01.10.2016)
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Journal Article
The effect of E chinacea purpurea on the pharmacokinetics of docetaxel
Goey, Andrew K. L., Meijerman, Irma, Rosing, Hilde, Burgers, Jacobus A., Mergui‐Roelvink, Marja, Keessen, Marianne, Marchetti, Serena, Beijnen, Jos H., Schellens, Jan H. M.
Published in British journal of clinical pharmacology (01.09.2013)
Published in British journal of clinical pharmacology (01.09.2013)
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Journal Article
Pharmacokinetics and excretion of 14C-omacetaxine in patients with advanced solid tumors
Nijenhuis, Cynthia M., Hellriegel, Edward, Beijnen, Jos H., Hershock, Diane, Huitema, Alwin D. R., Lucas, Luc, Mergui-Roelvink, Marja, Munteanu, Mihaela, Rabinovich-Guilatt, Laura, Robertson, Philmore, Rosing, Hilde, Spiegelstein, Ofer, Schellens, Jan H. M.
Published in Investigational new drugs (01.10.2016)
Published in Investigational new drugs (01.10.2016)
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Journal Article
Phase I study of lonafarnib (SCH66336) in combination with trastuzumab plus paclitaxel in Her2/neu overexpressing breast cancer: EORTC study 16023
Kerklaan, Bojana Milojkovic, Diéras, Veronique, Le Tourneau, Christophe, Mergui-Roelvink, Marja, Huitema, Alwin D. R., Rosing, Hilde, Beijnen, Jos H., Marreaud, Sandrine, Govaerts, Anne-Sophie, Piccart-Gebhart, Martine J., Schellens, Jan H. M., Awada, Ahmad
Published in Cancer chemotherapy and pharmacology (2013)
Published in Cancer chemotherapy and pharmacology (2013)
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Journal Article
Phase I study of olaparib in combination with carboplatin and/or paclitaxel in patients with advanced solid tumors
van der Noll, Ruud, Ang, Joo Ern, Jager, Agnes, Marchetti, Serena, Mergui-Roelvink, Marja, De Bono, Johann Sebastian, Lolkema, Martijn, Brunetto, Andre, Arkenau, Hendrik-Tobias, De Jonge, Maja J., van der Biessen, Diane, Tchakov, Ilian, Bowen, Karin, Schellens, Jan H. M.
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
Pharmacokinetics and excretion of 14C-lenvatinib in patients with advanced solid tumors or lymphomas
Dubbelman, Anne-Charlotte, Rosing, Hilde, Nijenhuis, Cynthia, Huitema, Alwin D. R., Mergui-Roelvink, Marja, Gupta, Anubha, Verbel, David, Thompson, Gary, Shumaker, Robert, Schellens, Jan H. M., Beijnen, Jos H.
Published in Investigational new drugs (01.02.2015)
Published in Investigational new drugs (01.02.2015)
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