Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species
Gigout, Anne, Harazin, Donata, Topping, Louise M, Merciris, Didier, Lindemann, Sven, Brenneis, Christian, Nissim, Ahuva
Published in Arthritis research & therapy (14.04.2021)
Published in Arthritis research & therapy (14.04.2021)
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Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization
Blanqué, Roland, Lepescheux, Liên, Auberval, Marielle, Minet, Dominique, Merciris, Didier, Cottereaux, Céline, Clément-Lacroix, Philippe, Delerive, Philippe, Namour, Florence
Published in BMC musculoskeletal disorders (03.09.2014)
Published in BMC musculoskeletal disorders (03.09.2014)
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Overexpression of the Transcriptional Factor Runx2 in Osteoblasts Abolishes the Anabolic Effect of Parathyroid Hormone in Vivo
Merciris, Didier, Marty, Caroline, Collet, Corinne, de Vernejoul, Marie-Christine, Geoffroy, Valerie
Published in The American journal of pathology (01.05.2007)
Published in The American journal of pathology (01.05.2007)
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Bone loss induced by Runx2 Over-expression in mice is blunted by osteoblastic over-expression of TIMP-1
Schiltz, Corinne, Prouillet, Christophe, Marty, Caroline, Merciris, Didier, Collet, Corinne, de Vernejoul, Marie-Christine, Geoffroy, Valérie
Published in Journal of cellular physiology (01.01.2010)
Published in Journal of cellular physiology (01.01.2010)
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Discovery of Clinical Candidate GLPG3970: A Potent and Selective Dual SIK2/SIK3 Inhibitor for the Treatment of Autoimmune and Inflammatory Diseases
Peixoto, Christophe, Joncour, Agnes, Temal-Laib, Taouès, Tirera, Amynata, Dos Santos, Aurélie, Jary, Hélène, Bucher, Denis, Laenen, Wendy, Pereira Fernandes, Anna, Lavazais, Stephanie, Delachaume, Carole, Merciris, Didier, Saccomani, Corinne, Drennan, Michael, López-Ramos, Miriam, Wakselman, Emanuelle, Dupont, Sonia, Borgonovi, Monica, Roca Magadan, Carlos, Monjardet, Alain, Brys, Reginald, De Vos, Steve, Andrews, Martin, Jimenez, Juan-Miguel, Amantini, David, Desroy, Nicolas
Published in Journal of medicinal chemistry (11.04.2024)
Published in Journal of medicinal chemistry (11.04.2024)
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Discovery of 9‑Cyclopropylethynyl-2-((S)‑1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1‑a]isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial
Labéguère, Frédéric, Dupont, Sonia, Alvey, Luke, Soulas, Florilène, Newsome, Gregory, Tirera, Amynata, Quenehen, Vanessa, Mai, Thi Thu Trang, Deprez, Pierre, Blanqué, Roland, Oste, Line, Le Tallec, Sandrine, De Vos, Steve, Hagers, Annick, Vandevelde, Ann, Nelles, Luc, Vandervoort, Nele, Conrath, Katja, Christophe, Thierry, van der Aar, Ellen, Wakselman, Emanuelle, Merciris, Didier, Cottereaux, Céline, da Costa, Cécile, Saniere, Laurent, Clement-Lacroix, Philippe, Jenkins, Laura, Milligan, Graeme, Fletcher, Stephen, Brys, Reginald, Gosmini, Romain
Published in Journal of medicinal chemistry (25.11.2020)
Published in Journal of medicinal chemistry (25.11.2020)
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188 Exploration of GLPG0634, the First Selective JAK1 Inhibitor, in Inflammatory Bowel Disease Is Supported by Early Clinical Results and Mouse DSS-Colitis Data
Galien, Rene, Merciris, Didier, Vanhoutte, Frédéric P, Delachaume, Carole, Namour, Florence S, Vayssière, Béatrice, Van der Aa, Annegret, Brys, Reginald, van't Klooster, Gerben A
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
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