Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
Fazakerley, Daniel J, Chaudhuri, Rima, Yang, Pengyi, Maghzal, Ghassan J, Thomas, Kristen C, Krycer, James R, Humphrey, Sean J, Parker, Benjamin L, Fisher-Wellman, Kelsey H, Meoli, Christopher C, Hoffman, Nolan J, Diskin, Ciana, Burchfield, James G, Cowley, Mark J, Kaplan, Warren, Modrusan, Zora, Kolumam, Ganesh, Yang, Jean Yh, Chen, Daniel L, Samocha-Bonet, Dorit, Greenfield, Jerry R, Hoehn, Kyle L, Stocker, Roland, James, David E
Published in eLife (06.02.2018)
Published in eLife (06.02.2018)
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Journal Article
The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle
Stöckli, Jacqueline, Meoli, Christopher C, Hoffman, Nolan J, Fazakerley, Daniel J, Pant, Himani, Cleasby, Mark E, Ma, Xiuquan, Kleinert, Maximilian, Brandon, Amanda E, Lopez, Jamie A, Cooney, Gregory J, James, David E
Published in Diabetes (New York, N.Y.) (01.06.2015)
Published in Diabetes (New York, N.Y.) (01.06.2015)
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Journal Article
Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes
Fazakerley, Daniel J., Naghiloo, Sheyda, Chaudhuri, Rima, Koumanov, Françoise, Burchfield, James G., Thomas, Kristen C., Krycer, James R., Prior, Matthew J., Parker, Ben L., Murrow, Beverley A., Stöckli, Jacqueline, Meoli, Christopher C., Holman, Geoffrey D., James, David E.
Published in The Journal of biological chemistry (25.09.2015)
Published in The Journal of biological chemistry (25.09.2015)
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Journal Article
Amplification and Demultiplexing in Insulin-regulated Akt Protein Kinase Pathway in Adipocytes
Tan, Shi-Xiong, Ng, Yvonne, Meoli, Christopher C., Kumar, Ansu, Khoo, Poh-Sim, Fazakerley, Daniel J., Junutula, Jagath R., Vali, Shireen, James, David E., Stöckli, Jacqueline
Published in The Journal of biological chemistry (24.02.2012)
Published in The Journal of biological chemistry (24.02.2012)
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Journal Article
DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake
Li, Jia, Cantley, James, Burchfield, James G., Meoli, Christopher C., Stöckli, Jacqueline, Whitworth, P. Tess, Pant, Himani, Chaudhuri, Rima, Groffen, Alexander J. A., Verhage, Matthijs, James, David E.
Published in Diabetologia (01.10.2014)
Published in Diabetologia (01.10.2014)
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Journal Article
Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic Dysfunction
WU, Lindsay E, MEOLI, Christopher C, XIROUCHAKI, Chrysovalantou E, STEFANIE MIKOLAIZAK, A, STÖCKLI, Jacqueline, KOLUMAM, Ganesh, VAN BRUGGEN, Nicholas, GAMBLE, Jennifer R, LE COUTEUR, David G, COONEY, Gregory J, ANDRIKOPOULOS, Sofianos, JAMES, David E, MANGIAFICO, Salvatore P, FAZAKERLEY, Daniel J, COGGER, Victoria C, MOHAMAD, Mashani, PANT, Himani, KANG, Myung-Jin, POWTER, Elizabeth, BURCHFIELD, James G
Published in Diabetes (New York, N.Y.) (01.08.2014)
Published in Diabetes (New York, N.Y.) (01.08.2014)
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Journal Article
Selective Insulin Resistance in Adipocytes
Tan, Shi-Xiong, Fisher-Wellman, Kelsey H., Fazakerley, Daniel J., Ng, Yvonne, Pant, Himani, Li, Jia, Meoli, Christopher C., Coster, Adelle C.F., Stöckli, Jacqueline, James, David E.
Published in The Journal of biological chemistry (01.05.2015)
Published in The Journal of biological chemistry (01.05.2015)
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Journal Article
High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice
Burchfield, James G, Kebede, Melkam A, Meoli, Christopher C, Stöckli, Jacqueline, Whitworth, P Tess, Wright, Amanda L, Hoffman, Nolan J, Minard, Annabel Y, Ma, Xiuquan, Krycer, James R, Nelson, Marin E, Tan, Shi-Xiong, Yau, Belinda, Thomas, Kristen C, Wee, Natalie K Y, Khor, Ee-Cheng, Enriquez, Ronaldo F, Vissel, Bryce, Biden, Trevor J, Baldock, Paul A, Hoehn, Kyle L, Cantley, James, Cooney, Gregory J, James, David E, Fazakerley, Daniel J
Published in The Journal of biological chemistry (13.04.2018)
Published in The Journal of biological chemistry (13.04.2018)
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Journal Article
Metabolomic analysis of insulin resistance across different mouse strains and diets
Stöckli, Jacqueline, Fisher-Wellman, Kelsey H., Chaudhuri, Rima, Zeng, Xiao-Yi, Fazakerley, Daniel J., Meoli, Christopher C., Thomas, Kristen C., Hoffman, Nolan J., Mangiafico, Salvatore P., Xirouchaki, Chrysovalantou E., Yang, Chieh-Hsin, Ilkayeva, Olga, Wong, Kari, Cooney, Gregory J., Andrikopoulos, Sofianos, Muoio, Deborah M., James, David E.
Published in The Journal of biological chemistry (24.11.2017)
Published in The Journal of biological chemistry (24.11.2017)
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Journal Article
Membrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPase
King, Gordon J., Stöckli, Jacqueline, Hu, Shu-Hong, Winnen, Brit, Duprez, Wilko G.A., Meoli, Christopher C., Junutula, Jagath R., Jarrott, Russell J., James, David E., Whitten, Andrew E., Martin, Jennifer L.
Published in The Journal of biological chemistry (30.11.2012)
Published in The Journal of biological chemistry (30.11.2012)
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Journal Article
Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity
Chaudhuri, Rima, Khoo, Poh Sim, Tonks, Katherine, Junutula, Jagath R, Kolumam, Ganesh, Modrusan, Zora, Samocha-Bonet, Dorit, Meoli, Christopher C, Hocking, Samantha, Fazakerley, Daniel J, Stöckli, Jacqueline, Hoehn, Kyle L, Greenfield, Jerry R, Yang, Jean Yee Hwa, James, David E
Published in NPJ systems biology and applications (12.11.2015)
Published in NPJ systems biology and applications (12.11.2015)
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Journal Article
High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice
Burchfield, James G., Kebede, Melkam A., Meoli, Christopher C., Stöckli, Jacqueline, Whitworth, P. Tess, Wright, Amanda L., Hoffman, Nolan J., Minard, Annabel Y., Ma, Xiuquan, Krycer, James R., Nelson, Marin E., Tan, Shi-Xiong, Yau, Belinda, Thomas, Kristen C., Wee, Natalie K.Y., Khor, Ee-Cheng, Enriquez, Ronaldo F., Vissel, Bryce, Biden, Trevor J., Baldock, Paul A., Hoehn, Kyle L., Cantley, James, Cooney, Gregory J., James, David E., Fazakerley, Daniel J.
Published in The Journal of biological chemistry (13.04.2018)
Published in The Journal of biological chemistry (13.04.2018)
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Journal Article