PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease‐protective variant PLCγ2 R522
Maguire, Emily, Menzies, Georgina E, Phillips, Thomas, Sasner, Michael, Williams, Harriet M, Czubala, Magdalena A, Evans, Neil, Cope, Emma L, Sims, Rebecca, Howell, Gareth R, Lloyd‐Evans, Emyr, Williams, Julie, Allen, Nicholas D, Taylor, Philip R
Published in The EMBO journal (01.09.2021)
Published in The EMBO journal (01.09.2021)
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Published in The FEBS journal (01.08.2023)
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Characterizing the original anti‐C5 function‐blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5
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Powell, Lydia C, Pritchard, Manon F, Ferguson, Elaine L, Powell, Kate A, Patel, Shree U, Rye, Phil D, Sakellakou, Stavroula-Melina, Buurma, Niklaas J, Brilliant, Charles D, Copping, Jack M, Menzies, Georgina E, Lewis, Paul D, Hill, Katja E, Thomas, David W
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A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease
Pritchard, Manon F, Powell, Lydia C, Menzies, Georgina E, Lewis, Paul D, Hawkins, Karl, Wright, Chris, Doull, Iolo, Walsh, Timothy R, Onsøyen, Edvar, Dessen, Arne, Myrvold, Rolf, Rye, Philip D, Myrset, Astrid H, Stevens, Howard N. E, Hodges, Lee A, MacGregor, Gordon, Neilly, James B, Hill, Katja E, Thomas, David W
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Published in Molecular pharmaceutics (07.03.2016)
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Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort
Grama, Steluta, Willcocks, Isabella, Hubert, John J, Pardiñas, Antonio F, Legge, Sophie E, Bracher-Smith, Matthew, Menzies, Georgina E, Hall, Lynsey S, Pocklington, Andrew J, Anney, Richard J L, Bray, Nicholas J, Escott-Price, Valentina, Caseras, Xavier
Published in Translational psychiatry (09.09.2020)
Published in Translational psychiatry (09.09.2020)
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Benefits and Challenges of Rare Genetic Variation in Alzheimer’s Disease
Grozeva, Detelina, Saad, Salha, Menzies, Georgina E., Sims, Rebecca
Published in Current genetic medicine reports (01.03.2019)
Published in Current genetic medicine reports (01.03.2019)
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Fourier transform infrared for noninvasive optical diagnosis of oral, oropharyngeal, and laryngeal cancer
Menzies, Georgina E, Fox, Hannah R, Marnane, Conor, Pope, Laysan, Prabhu, Vinod, Winter, Stuart, Derrick, Anna V, Lewis, Paul D
Published in Translational research : the journal of laboratory and clinical medicine (2014)
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MutAIT: an online genetic toxicology data portal and analysis tools
Avancini, Daniele, Menzies, Georgina E, Morgan, Claire, Wills, John, Johnson, George E, White, Paul A, Lewis, Paul D
Published in Mutagenesis (01.05.2016)
Published in Mutagenesis (01.05.2016)
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MOLECULAR DYNAMIC MODELLING OF A NOVEL PLCG2 VARIANT REVEALS KEY PROTEIN STRUCTURAL DIFFERENCES
Menzies, Georgina E., Sims, Rebecca, Williams, Julie
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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The Alzheimer’s disease protective R522 variant of PLCg2, consistently enhances PLCγ2 activation, depleting PI(4,5)P2 levels and altering cell function in in vitro and in vivo assays
Philips, Thomas Ernest James, Maguire, Emily, Menzies, Georgina E, Sasner, Michael, Williams, Harriet M, Czubala, Magdalena, Evans, Neil, Cope, Emma L, Sims, Rebecca, Howell, Gareth, Lloyd‐Evans, Emyr, Williams, Julie, Allen, Nicholas D, Taylor, Philip
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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The Alzheimer’s disease protective R522 variant of PLCg2, consistently enhances PLCγ2 activation, depleting PI(4,5)P 2 levels and altering cell function in in vitro and in vivo assays: Developing topics
Philips, Thomas Ernest James, Maguire, Emily, Menzies, Georgina E, Sasner, Michael, Williams, Harriet M, Czubala, Magdalena, Evans, Neil, Cope, Emma L, Sims, Rebecca, Howell, Gareth, Lloyd‐Evans, Emyr, Williams, Julie, Allen, Nicholas D, Taylor, Philip
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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O5‐10‐01: ENHANCED FUNCTION OF PLCG2 VARIANT P522R IN MACROPHAGES AND MICROGLIA IS ASSOCIATED WITH PROTECTION FROM ALZHEIMER'S DISEASE
Maguire, Emily, Menzies, Georgina E., James Philips, Thomas Ernest, Cope, Emma L., Czubala, Magdalena, Evans, Neil, Howell, Gareth, Williams, Harriet M., Sasner, Michael, Lloyd-Evans, Emyr, Sims, Rebecca, Williams, Julie, Allen, Nicholas D., Taylor, Philip
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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P2‐112: NEXT GENERATION EXOME SEQUENCING IN A LARGE SAMPLE OF ALZHEIMER'S PATIENTS
Grozeva, Detelina, Frizzati, Aura, Sims, Rebecca, Morgan, Taniesha, Raybould, Rachel, Rees, Elliott, Majounie, Elisa, Denning, Nicola, Meggy, Alun, Marshall, Rachel, Beaumont, Bartholomew, Nash, William, Davies, Chloe, Morgan, Joanne, Leonenko, Ganna, Menzies, Georgina E., Badarinarayan, Nandini, Escott-Price, Valentina, Williams, Julie
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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