D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization
Böttcher, Martin, Renner, Kathrin, Berger, Raffaela, Mentz, Kristin, Thomas, Simone, Cardenas-Conejo, Zugey Elizabeth, Dettmer, Katja, Oefner, Peter J., Mackensen, Andreas, Kreutz, Marina, Mougiakakos, Dimitrios
Published in Oncoimmunology (03.07.2018)
Published in Oncoimmunology (03.07.2018)
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Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis
Böttcher, Martin, Bruns, Heiko, Völkl, Simon, Lu, Junyan, Chartomatsidou, Elisavet, Papakonstantinou, Nikos, Mentz, Kristin, Büttner-Herold, Maike, Zenz, Thorsten, Herling, Marco, Huber, Wolfgang, Ghia, Paolo, Stamatopoulos, Kostas, Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Journal for immunotherapy of cancer (01.04.2021)
Published in Journal for immunotherapy of cancer (01.04.2021)
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Effective elimination of acute myeloid leukemic cells by recombinant bispecific antibody derivatives directed against CD33 and CD16
Singer, Heiko, Kellner, Christian, Lanig, Harald, Aigner, Michael, Stockmeyer, Bernhard, Oduncu, Fuat, Schwemmlein, Michael, Stein, Christoph, Mentz, Kristin, Mackensen, Andreas, Fey, Georg H
Published in Journal of immunotherapy (1997) (01.07.2010)
Published in Journal of immunotherapy (1997) (01.07.2010)
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A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting
Schubert, Ingo, Kellner, Christian, Stein, Christoph, Kügler, Markus, Schwenkert, Michael, Saul, Domenica, Mentz, Kristin, Singer, Heiko, Stockmeyer, Bernhard, Hillen, Wolfgang, Mackensen, Andreas, Fey, Georg H.
Published in mAbs (01.01.2011)
Published in mAbs (01.01.2011)
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Effects of the STAMP-inhibitor asciminib on T cell activation and metabolic fitness compared to tyrosine kinase inhibition by imatinib, dasatinib, and nilotinib
Häselbarth, Lukas, Karow, Axel, Mentz, Kristin, Böttcher, Martin, Roche-Lancaster, Oisin, Krumbholz, Manuela, Jitschin, Regina, Mougiakakos, Dimitrios, Metzler, Markus
Published in Cancer Immunology, Immunotherapy (01.06.2023)
Published in Cancer Immunology, Immunotherapy (01.06.2023)
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Microenvironmental Triggers Induce a Chemoresistant, Differentiated Subset of S100A8/A9high AML Cells Via the Jak/STAT3 Signaling Axis
Boettcher, Martin, Panagiotidis, Konstantinos, Mentz, Kristin, Voelkl, Simon, Bruns, Heiko, Slany, Robert, Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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A recombinant trispecific single‐chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting
Kügler, Markus, Stein, Christoph, Kellner, Christian, Mentz, Kristin, Saul, Domenica, Schwenkert, Michael, Schubert, Ingo, Singer, Heiko, Oduncu, Fuat, Stockmeyer, Bernhard, Mackensen, Andreas, Fey, Georg H.
Published in British journal of haematology (01.09.2010)
Published in British journal of haematology (01.09.2010)
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Journal Article
Novel conjugates of single‐chain Fv antibody fragments specific for stem cell antigen CD123 mediate potent death of acute myeloid leukaemia cells
Stein, Christoph, Kellner, Christian, Kügler, Markus, Reiff, Nina, Mentz, Kristin, Schwenkert, Michael, Stockmeyer, Bernhard, Mackensen, Andreas, Fey, Georg H.
Published in British journal of haematology (01.03.2010)
Published in British journal of haematology (01.03.2010)
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Heterodimeric bispecific antibody-derivatives against CD19 and CD16 induce effective antibody-dependent cellular cytotoxicity against B-lymphoid tumor cells
Kellner, Christian, Bruenke, Joerg, Horner, Heike, Schubert, Joerg, Schwenkert, Michael, Mentz, Kristin, Barbin, Karin, Stein, Christoph, Peipp, Matthias, Stockmeyer, Bernhard, Fey, Georg H
Published in Cancer letters (28.04.2011)
Published in Cancer letters (28.04.2011)
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A novel CD19-directed recombinant bispecific antibody derivative with enhanced immune effector functions for human leukemic cells
Kellner, Christian, Bruenke, Joerg, Stieglmaier, Julia, Schwemmlein, Michael, Schwenkert, Michael, Singer, Heiko, Mentz, Kristin, Peipp, Matthias, Lang, Peter, Oduncu, Fuat, Stockmeyer, Bernhard, Fey, Georg H
Published in Journal of immunotherapy (1997) (01.11.2008)
Published in Journal of immunotherapy (1997) (01.11.2008)
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