The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future
Mennen, Steven M, Alhambra, Carolina, Allen, C. Liana, Barberis, Mario, Berritt, Simon, Brandt, Thomas A, Campbell, Andrew D, Castañón, Jesús, Cherney, Alan H, Christensen, Melodie, Damon, David B, Eugenio de Diego, J, García-Cerrada, Susana, García-Losada, Pablo, Haro, Rubén, Janey, Jacob, Leitch, David C, Li, Ling, Liu, Fangfang, Lobben, Paul C, MacMillan, David W. C, Magano, Javier, McInturff, Emma, Monfette, Sebastien, Post, Ronald J, Schultz, Danielle, Sitter, Barbara J, Stevens, Jason M, Strambeanu, Iulia I, Twilton, Jack, Wang, Ke, Zajac, Matthew A
Published in Organic process research & development (21.06.2019)
Published in Organic process research & development (21.06.2019)
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Journal Article
Asymmetric Catalysis Mediated by Synthetic Peptides
Davie, Elizabeth A. Colby, Mennen, Steven M, Xu, Yingju, Miller, Scott J
Published in Chemical reviews (01.12.2007)
Published in Chemical reviews (01.12.2007)
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Journal Article
Enantioselective Total Synthesis of (+)-Gliocladine C: Convergent Construction of Cyclotryptamine-Fused Polyoxopiperazines and a General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors
DeLorbe, John E, Jabri, Salman Y, Mennen, Steven M, Overman, Larry E, Zhang, Fang-Li
Published in Journal of the American Chemical Society (04.05.2011)
Published in Journal of the American Chemical Society (04.05.2011)
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Journal Article
General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors: Enantioselective Total Syntheses of (+)- and (−)-Gliocladine C, (+)-Leptosin D, (+)-T988C, (+)-Bionectin A, and (+)-Gliocladin A
DeLorbe, John E, Horne, David, Jove, Richard, Mennen, Steven M, Nam, Sangkil, Zhang, Fang-Li, Overman, Larry E
Published in Journal of the American Chemical Society (13.03.2013)
Published in Journal of the American Chemical Society (13.03.2013)
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Journal Article
Synthesis of the Hydrazinyl Pyridine Intermediate: Phase-Appropriate Delivery
Wilsily, Ashraf, Mennen, Steven M, Cosbie, Andrew, Milne, Jacqueline E
Published in Organic process research & development (15.09.2017)
Published in Organic process research & development (15.09.2017)
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Journal Article
Xantphos as a Branch-Selective Ligand for the Acyclic sec-Alkyl Negishi Cross-Coupling of Heteroaryl Halides
Cherney, Alan H, Hedley, Simon J, Mennen, Steven M, Tedrow, Jason S
Published in Organometallics (14.01.2019)
Published in Organometallics (14.01.2019)
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Journal Article
Process Development and Protein Engineering Enhanced Nitroreductase-Catalyzed Reduction of 2‑Methyl-5-nitro-pyridine
Bornadel, Amin, Bisagni, Serena, Pushpanath, Ahir, Slabu, Iustina, LePaih, Jacques, Cherney, Alan H, Mennen, Steven M, Hedley, Simon J, Tedrow, Jason, Dominguez, Beatriz
Published in Organic process research & development (19.03.2021)
Published in Organic process research & development (19.03.2021)
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Journal Article
Scalable Synthesis of 6,6-Dimethylbicyclo[3.1.0]hexan-3-one
Mennen, Steven M., Arunachalampillai, Athimoolam, Choquette, Deborah M., Muppalla, Harikrishna, Sheena, Krishna
Published in Synlett (23.10.2017)
Published in Synlett (23.10.2017)
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Journal Article
Development of a Factory Process for Omecamtiv Mecarbil, a Novel Cardiac Myosin Activator
Caille, Seb, Allgeier, Alan M, Bernard, Charles, Correll, Tiffany L, Cosbie, Andrew, Crockett, Richard D, Cui, Sheng, Faul, Margaret M, Hansen, Karl B, Huggins, Seth, Langille, Neil, Mennen, Steven M, Morgan, Bradley P, Morrison, Henry, Muci, Alexander, Nagapudi, Karthik, Quasdorf, Kyle, Ranganathan, Krishnakumar, Roosen, Philipp, Shi, Xianqing, Thiel, Oliver R, Wang, Fang, Tvetan, Justin T, Woo, Jacqueline C. S, Wu, Steven, Walker, Shawn D
Published in Organic process research & development (16.08.2019)
Published in Organic process research & development (16.08.2019)
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Journal Article
Synthesis of 4‑Substituted Phthalazin-1(2H)‑ones from 2‑Acylbenzoic Acids: Controlling Hydrazine in a Pharmaceutical Intermediate through PAT-Guided Process Development
Mennen, Steven M, Mak-Jurkauskas, Melody L, Bio, Matthew M, Hollis, L. Steven, Nadeau, Kelly A, Clausen, Andrew M, Hansen, Karl B
Published in Organic process research & development (17.07.2015)
Published in Organic process research & development (17.07.2015)
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Journal Article
A peptide-catalyzed asymmetric Stetter reaction
Mennen, SM, Blank, JT, Tran-Dube, MB, Imbriglio, JE, Miller, SJ
Published in Chemical communications (Cambridge, England) (14.01.2005)
Published in Chemical communications (Cambridge, England) (14.01.2005)
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Journal Article
Synthesis of aziridinomitosenes through base-catalyzed conjugate addition
Tsuboike, Kazunari, Guerin, David J., Mennen, Steven M., Miller, Scott J.
Published in Tetrahedron (16.08.2004)
Published in Tetrahedron (16.08.2004)
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Journal Article
Chemo-Enzymatic Cascades
Slabu, Iustina, Bisagni, Serena, Hedley, Simon J, Cherney, Alan H, Pushpanath, Ahir, Bornadel, Amin, LePaih, Jacques, Mennen, Steven M, Dominguez, Beatriz
Published in Applied Biocatalysis (2021)
Published in Applied Biocatalysis (2021)
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Book Chapter
친핵성 방향족 치환에 의한 디올 탈대칭화
ROTHELI ANDREAS RENE, TEDROW JASON S, COHEN CAROLYN, DENNIS JOSEPH, DORNAN PETER K, BEAVER MATTHEW G, MENNEN STEVEN, LANGILLE NEIL FRED
Year of Publication 03.05.2023
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Year of Publication 03.05.2023
Patent
Synergistic nitroreductase/vanadium catalysis enables chemoselective nitro reductions to anilines in the absence of hydrogen gas
Bisagni, Serena, Bornadel, Amin, Cherney, Alan H., Hedley, Simon J., LePaih, Jacques, Mennen, Steven M., Pushpanath, Ahir, Slabu, Iustina, Tedrow, Jason, Dominguez, Beatriz
Published in Current research in chemical biology (2022)
Published in Current research in chemical biology (2022)
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Journal Article
심장 트로포닌 활성제의 다형체 및 공결정
MENNEN STEVEN M, WRIGHT MARK, WILSILY ASHRAF, AZALI STEPHANIE, CHAVES MARY, SULEIMAN OSAMA, KELLY RON C, REID DARREN L
Year of Publication 07.01.2022
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Year of Publication 07.01.2022
Patent