Transforming activities of the NUP98-KMT2A fusion gene associated with myelodysplasia and acute myeloid leukemia
Fisher, James N, Thanasopoulou, Angeliki, Juge, Sabine, Tzankov, Alexandar, Bagger, Frederik O, Mendez, Max A, Peters, Antoine H F M, Schwaller, Juerg
Published in Haematologica (Roma) (01.07.2020)
Published in Haematologica (Roma) (01.07.2020)
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Journal Article
High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex
Zhou, Xiang, Besse, Andrej, Peter, Jessica, Steinhardt, Maximilian Johannes, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Stanojkovska, Emilia, Xiao, Xianghui, Hornburger, Hannah, Haertle, Larissa, Lopez, Max Mendez, Munawar, Umair, Riedel, Angela, Han, Seungbin, Maurits, Elmer, Overkleeft, Herman S, Florea, Bogdan, Einsele, Hermann, Kortüm, K Martin, Driessen, Christoph, Besse, Lenka, Rasche, Leo
Published in Haematologica (Roma) (01.06.2023)
Published in Haematologica (Roma) (01.06.2023)
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Journal Article
Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors
Besse, Andrej, Besse, Lenka, Kraus, Marianne, Mendez-Lopez, Max, Bader, Jürgen, Xin, Bo-Tao, de Bruin, Gerjan, Maurits, Elmer, Overkleeft, Herman S, Driessen, Christoph
Published in Cell chemical biology (21.03.2019)
Published in Cell chemical biology (21.03.2019)
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Journal Article
A metabolic switch in proteasome inhibitor-resistant multiple myeloma ensures higher mitochondrial metabolism, protein folding and sphingomyelin synthesis
Besse, Lenka, Besse, Andrej, Mendez-Lopez, Max, Vasickova, Katerina, Sedlackova, Miroslava, Vanhara, Petr, Kraus, Marianne, Bader, Jürgen, Ferreira, Renan B, Castellano, Ronald K, Law, Brian K, Driessen, Christoph
Published in Haematologica (Roma) (01.09.2019)
Published in Haematologica (Roma) (01.09.2019)
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Journal Article
Immunoproteasome Activity in Chronic Lymphocytic Leukemia as a Target of the Immunoproteasome-Selective Inhibitors
Besse, Andrej, Kraus, Marianne, Mendez-Lopez, Max, Maurits, Elmer, Overkleeft, Herman S, Driessen, Christoph, Besse, Lenka
Published in Cells (Basel, Switzerland) (01.03.2022)
Published in Cells (Basel, Switzerland) (01.03.2022)
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Journal Article
TCT-595 Transcaval Access: Bleeding Is No Longer A Concern
Chainani, Vinod, Mendez, Max, Knopf, David
Published in Journal of the American College of Cardiology (31.10.2017)
Published in Journal of the American College of Cardiology (31.10.2017)
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Journal Article
All-Trans-Retinoic Acid Prevents Carfilzomib-Induced Cardiotoxicity By Decreasing Activation of the Renin-Angiotensin System
Mendez, Max A, Besse, Andrej, Florea, Bogdan I., Zuppinger, Christian, Overkleeft, Herman S., Besse, Lenka, Driessen, Christoph
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
P-158: Carfilzomib-induced acute cardiotoxicity is mediated through angiotensin and caused by cardiomyocyte energy depletion
Mendez, Max, Andrej, Besse, Florea, Bogdan, Christian, Zuppinger, Overkleeft, Hermen, Lenka, Besse, Driessen, Christoph
Published in Clinical lymphoma, myeloma and leukemia (01.10.2021)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2021)
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Journal Article
Proteasome inhibition by Carfilzomib, but not by Bortezomib, induces a specific, proteasome subunit-dependent impairment in cardiac contractility
Mendez, Max, Besse, Andrej, Besse, Lenka, Florea, Bogdan, Christian, Zuppinger, Overkleeft, Herman S., Driessen, Christoph
Published in Clinical lymphoma, myeloma and leukemia (01.10.2019)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2019)
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Journal Article
Abstract 7191: Targeting IGF1R/INSR pathway with approved ALK inhibitors inhibits AKT signaling and overcomes proteasome inhibitor resistance in multiple myeloma
Besse, Andrej, Totu, Tiberiu, Kraus, Marianne, Janssen, Anthonius P., Veprkova, Jana, Lopez, Max Mendez, Slaby, Ondrej, Buljan, Marija, van der Stelt, Mario, Driessen, Christoph, Besse, Lenka
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Targeting IGF1R/Insr Pathway with Approved ALK-Inhibitors Overcomes Proteasome Inhibitor Resistance in Multiple Myeloma
Mendez-Lopez, Max Alberto, Besse, Andrej, Totu, Tiberiu, Kraus, Marianne, Janssen, Anthonius P.A., Buljan, Marija, Van Der Stelt, Mario, Besse, Lenka, Driessen, Christoph
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
HIV protease inhibitors for the treatment of multiple myeloma
Mendez-Lopez, Max, Sutter, Tabea, Driessen, Christoph, Besse, Lenka
Published in Clinical advances in hematology & oncology (01.11.2019)
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Published in Clinical advances in hematology & oncology (01.11.2019)
Journal Article
Carfilzomib Induces Cardiotoxicity Via ß5/ß2-Specific Proteasome Subunit Inhibition Pattern
Mendez-Lopez, Max A, Besse, Andrej, Florea, Bogdan, Zuppinger, Christian, Overkleeft, Herman, Driessen, Christoph, Besse, Lenka
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Prevalence of the fibrinogen β-chain, angiotensin-converting enzyme and plasminogen activator inhibitor-1 polymorphisms in Costa Rican young adults with thrombotic disease
Hidalgo, Andrea, Salazar-Sanchez, Lizbeth, Cartin, Mayra, Mendez, Max, Arauz, Jorge, Parajeles, Alexander
Published in Cell biochemistry and function (01.07.2010)
Published in Cell biochemistry and function (01.07.2010)
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Journal Article
High-Dose Carfilzomib Recaptures Response in Relapsed/Refractory Multiple Myeloma Resistant to Low-Dose Carfilzomib By Co-Inhibiting β2 Subunit of Proteasome Complex: The First in Human Evidence
Zhou, Xiang, Besse, Andrej, Peter, Jessica, Mendez Lopez, Max, Haertle, Larissa, Munawar, Umair, Han, Seungbin, Maurits, Elmer, Overkleeft, Herman S., Einsele, Hermann, Driessen, Christoph, Kortuem, Martin, Besse, Lenka, Rasche, Leo
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to low-dose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex
Zhou, Xiang, Besse, Andrej, Peter, Jessica, Steinhardt, Maximilian Johannes, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Stanojkovska, Emilia, Xiao, Xianghui, Hornburger, Hannah, Haertle, Larissa, Mendez-Lopez, Max, Munawar, Umair, Riedel, Angela, Han, Seungbin, Maurits, Elmer, Overkleeft, Herman S., Florea, Bogdan, Einsele, Hermann, Kortüm, K. Martin, Driessen, Christoph, Besse, Lenka, Rasche, Leo
Published in Haematologica (Roma) (01.06.2023)
Published in Haematologica (Roma) (01.06.2023)
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Journal Article
Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
Yurchenko, Andrey A, Pop, Oltin T, Ighilahriz, Meriem, Padioleau, Ismael, Rajabi, Fatemeh, Sharpe, Hayley J, Poulalhon, Nicolas, Dreno, Brigitte, Khammari, Amir, Delord, Marc, Alberti, Antonio, Soufir, Nadem, Battistella, Maxime, Mourah, Samia, Bouquet, Fanny, Savina, Ariel, Besse, Andrej, Mendez-Lopez, Max, Grange, Florent, Monestier, Sandrine, Mortier, Laurent, Meyer, Nicolas, Dutriaux, Caroline, Robert, Caroline, Saiag, Philippe, Herms, Florian, Lambert, Jerome, de Sauvage, Frederic J, Dumaz, Nicolas, Flatz, Lukas, Basset-Seguin, Nicole, Nikolaev, Sergey I
Published in Clinical cancer research (01.04.2022)
Published in Clinical cancer research (01.04.2022)
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Journal Article