Generation of Functional Human Pancreatic β Cells In Vitro
Pagliuca, Felicia W., Millman, Jeffrey R., Gürtler, Mads, Segel, Michael, Van Dervort, Alana, Ryu, Jennifer Hyoje, Peterson, Quinn P., Greiner, Dale, Melton, Douglas A.
Published in Cell (09.10.2014)
Published in Cell (09.10.2014)
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Recovery from diabetes in mice by beta cell regeneration
Nir, Tomer, Melton, Douglas A, Dor, Yuval
Published in The Journal of clinical investigation (01.09.2007)
Published in The Journal of clinical investigation (01.09.2007)
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In vivo reprogramming of adult pancreatic exocrine cells to β-cells
Zhou, Qiao, Brown, Juliana, Kanarek, Andrew, Rajagopal, Jayaraj, Melton, Douglas A.
Published in Nature (London) (02.10.2008)
Published in Nature (London) (02.10.2008)
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A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure
Baron, Maayan, Veres, Adrian, Wolock, Samuel L., Faust, Aubrey L., Gaujoux, Renaud, Vetere, Amedeo, Ryu, Jennifer Hyoje, Wagner, Bridget K., Shen-Orr, Shai S., Klein, Allon M., Melton, Douglas A., Yanai, Itai
Published in Cell systems (26.10.2016)
Published in Cell systems (26.10.2016)
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Generation of stem cell-derived β-cells from patients with type 1 diabetes
Millman, Jeffrey R., Xie, Chunhui, Van Dervort, Alana, Gürtler, Mads, Pagliuca, Felicia W., Melton, Douglas A.
Published in Nature communications (10.05.2016)
Published in Nature communications (10.05.2016)
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Circadian Entrainment Triggers Maturation of Human In Vitro Islets
Alvarez-Dominguez, Juan R., Donaghey, Julie, Rasouli, Niloofar, Kenty, Jennifer H.R., Helman, Aharon, Charlton, Jocelyn, Straubhaar, Juerg R., Meissner, Alexander, Melton, Douglas A.
Published in Cell stem cell (02.01.2020)
Published in Cell stem cell (02.01.2020)
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Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq
Kotliar, Dylan, Veres, Adrian, Nagy, M Aurel, Tabrizi, Shervin, Hodis, Eran, Melton, Douglas A, Sabeti, Pardis C
Published in eLife (08.07.2019)
Published in eLife (08.07.2019)
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Charting cellular identity during human in vitro β-cell differentiation
Veres, Adrian, Faust, Aubrey L., Bushnell, Henry L., Engquist, Elise N., Kenty, Jennifer Hyoje-Ryu, Harb, George, Poh, Yeh-Chuin, Sintov, Elad, Gürtler, Mads, Pagliuca, Felicia W., Peterson, Quinn P., Melton, Douglas A.
Published in Nature (London) (16.05.2019)
Published in Nature (London) (16.05.2019)
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Generation of hypoimmunogenic human pluripotent stem cells
Han, Xiao, Wang, Mengning, Duan, Songwei, Franco, Paul J., Kenty, Jennifer Hyoje-Ryu, Hedrick, Preston, Xia, Yulei, Allen, Alana, Ferreira, Leonardo M. R., Strominger, Jack L., Melton, Douglas A., Meissner, Torsten B., Cowan, Chad A.
Published in Proceedings of the National Academy of Sciences - PNAS (21.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (21.05.2019)
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A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion
Helman, Aharon, Cangelosi, Andrew L., Davis, Jeffrey C., Pham, Quan, Rothman, Arielle, Faust, Aubrey L., Straubhaar, Juerg R., Sabatini, David M., Melton, Douglas A.
Published in Cell metabolism (05.05.2020)
Published in Cell metabolism (05.05.2020)
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MARIS: method for analyzing RNA following intracellular sorting
Hrvatin, Siniša, Deng, Francis, O'Donnell, Charles W, Gifford, David K, Melton, Douglas A
Published in PloS one (03.03.2014)
Published in PloS one (03.03.2014)
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