Editorial to the Special Issue: “Dysregulation of Human Molecular and Metabolic Mechanisms Resulting in Oxidative Stress and Damage Generation in the Space Environment”
Goodwin, Thomas J., Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (09.06.2022)
Published in International journal of molecular sciences (09.06.2022)
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Journal Article
Oxidative Stress and Space Biology: An Organ-Based Approach
Goodwin, Thomas J, Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (23.03.2018)
Published in International journal of molecular sciences (23.03.2018)
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Journal Article
KLF5 Is Induced by FOXO1 and Causes Oxidative Stress and Diabetic Cardiomyopathy
Kyriazis, Ioannis D, Hoffman, Matthew, Gaignebet, Lea, Lucchese, Anna Maria, Markopoulou, Eftychia, Palioura, Dimitra, Wang, Chao, Bannister, Thomas D, Christofidou-Solomidou, Melpo, Oka, Shin-Ichi, Sadoshima, Junichi, Koch, Walter J, Goldberg, Ira J, Yang, Vincent W, Bialkowska, Agnieszka B, Kararigas, Georgios, Drosatos, Konstantinos
Published in Circulation research (05.02.2021)
Published in Circulation research (05.02.2021)
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Journal Article
Dietary Flaxseed Protects Against Lung Ischemia Reperfusion Injury Via Inhibition of Apoptosis and Inflammation in a Murine Model
Razi, Syed S., M.D, Latif, Mohammed J., M.D, Li, Xiaogui, Ph.D, Afthinos, John N., M.D, Ippagunta, Nikalesh, M.D, Schwartz, Gary, M.D, Sagalovich, Daniel, M.S, Belsley, Scott J., M.D, Connery, Cliff P., M.D, Jour, George, M.D, Christofidou-Solomidou, Melpo, Ph.D, Bhora, Faiz Y., M.D
Published in The Journal of surgical research (01.11.2011)
Published in The Journal of surgical research (01.11.2011)
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Journal Article
Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice
Fan, Ming-Hui, Zhu, Qiang, Li, Hui-Hua, Ra, Hyun-Jeong, Majumdar, Sonali, Gulick, Dexter L., Jerome, Jacob A., Madsen, Daniel H., Christofidou-Solomidou, Melpo, Speicher, David W., Bachovchin, William W., Feghali-Bostwick, Carol, Puré, Ellen
Published in The Journal of biological chemistry (08.04.2016)
Published in The Journal of biological chemistry (08.04.2016)
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Journal Article
Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells
Pietrofesa, Ralph A, Chatterjee, Shampa, Kadariya, Yuwaraj, Testa, Joseph R, Albelda, Steven M, Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (03.09.2022)
Published in International journal of molecular sciences (03.09.2022)
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Journal Article
Erythrocytosis and Pulmonary Hypertension in a Mouse Model of Human HIF2A Gain of Function Mutation
Tan, Qiulin, Kerestes, Heddy, Percy, Melanie J., Pietrofesa, Ralph, Chen, Li, Khurana, Tejvir S., Christofidou-Solomidou, Melpo, Lappin, Terence R.J., Lee, Frank S.
Published in The Journal of biological chemistry (14.06.2013)
Published in The Journal of biological chemistry (14.06.2013)
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Journal Article
KL4-surfactant prevents hyperoxic and LPS-induced lung injury in mice
Kinniry, Paul, Pick, Jeremy, Stephens, Scott, Jain, Deepika, Solomides, Charalambos C., Niven, Ralph, Segal, Robert, Christofidou-Solomidou, Melpo
Published in Pediatric pulmonology (01.10.2006)
Published in Pediatric pulmonology (01.10.2006)
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Journal Article
Late Inflammation Induced by Asbestiform Fibers in Mice Is Ameliorated by a Small Molecule Synthetic Lignan
Badger, Reagan, Park, Kyewon, Pietrofesa, Ralph A, Christofidou-Solomidou, Melpo, Serve, Kinta M
Published in International journal of molecular sciences (12.10.2021)
Published in International journal of molecular sciences (12.10.2021)
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Journal Article
Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)
Pietrofesa, Ralph A, Velalopoulou, Anastasia, Albelda, Steven M, Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (01.03.2016)
Published in International journal of molecular sciences (01.03.2016)
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Journal Article
Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation
Rom, Slava, Zuluaga-Ramirez, Viviana, Reichenbach, Nancy L, Erickson, Michelle A, Winfield, Malika, Gajghate, Sachin, Christofidou-Solomidou, Melpo, Jordan-Sciutto, Kelly L, Persidsky, Yuri
Published in Journal of neuroinflammation (27.01.2018)
Published in Journal of neuroinflammation (27.01.2018)
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Journal Article
Assessment of a Small Molecule Synthetic Lignan in Enhancing Oxidative Balance and Decreasing Lipid Accumulation in Human Retinal Pigment Epithelia
Dhingra, Anuradha, Sharp, Rachel C, Kim, Taewan, Popov, Anatoliy V, Ying, Gui-Shuang, Pietrofesa, Ralph A, Park, Kyewon, Christofidou-Solomidou, Melpo, Boesze-Battaglia, Kathleen
Published in International journal of molecular sciences (28.05.2021)
Published in International journal of molecular sciences (28.05.2021)
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Journal Article
Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy
Kokkinaki, Dimitra, Hoffman, Matthew, Kalliora, Charikleia, Kyriazis, Ioannis D., Maning, Jennifer, Lucchese, Anna Maria, Shanmughapriya, Santhanam, Tomar, Dhanendra, Park, Joon Young, Wang, Hong, Yang, Xiao-Feng, Madesh, Muniswamy, Lymperopoulos, Anastasios, Koch, Walter J., Christofidou-Solomidou, Melpo, Drosatos, Konstantinos
Published in Journal of molecular and cellular cardiology (01.02.2019)
Published in Journal of molecular and cellular cardiology (01.02.2019)
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Journal Article
Gamma-irradiation produces active chlorine species (ACS) in physiological solutions: Secoisolariciresinol diglucoside (SDG) scavenges ACS - A novel mechanism of DNA radioprotection
Mishra, Om P., Popov, Anatoliy V., Pietrofesa, Ralph A., Christofidou-Solomidou, Melpo
Published in Biochimica et biophysica acta (01.09.2016)
Published in Biochimica et biophysica acta (01.09.2016)
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Journal Article
Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605)
Pietrofesa, Ralph A, Park, Kyewon, Mishra, Om P, Johnson-McDaniel, Darrah, Myerson, Jacob W, Shuvaev, Vladimir V, Arguiri, Evguenia, Chatterjee, Shampa, Moorthy, Ganesh S, Zuppa, Athena, Hwang, Wei-Ting, Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (31.08.2021)
Published in International journal of molecular sciences (31.08.2021)
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Journal Article
The Flaxseed-Derived Lignan Phenolic Secoisolariciresinol Diglucoside (SDG) Protects Non-Malignant Lung Cells from Radiation Damage
Velalopoulou, Anastasia, Tyagi, Sonia, Pietrofesa, Ralph A, Arguiri, Evguenia, Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (01.01.2016)
Published in International journal of molecular sciences (01.01.2016)
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Journal Article
LGM2605 Reduces Space Radiation-Induced NLRP3 Inflammasome Activation and Damage in In Vitro Lung Vascular Networks
Chatterjee, Shampa, Pietrofesa, Ralph A, Park, Kyewon, Tao, Jian-Qin, Carabe-Fernandez, Alejandro, Berman, Abigail T, Koumenis, Constantinos, Sielecki, Thais, Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (05.01.2019)
Published in International journal of molecular sciences (05.01.2019)
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Journal Article
Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo
Shuvaev, Vladimir V, Han, Jingyan, Tliba, Samira, Arguiri, Evguenia, Christofidou-Solomidou, Melpo, Ramirez, Servio H, Dykstra, Holly, Persidsky, Yuri, Atochin, Dmitriy N, Huang, Paul L, Muzykantov, Vladimir R
Published in PloS one (11.10.2013)
Published in PloS one (11.10.2013)
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Journal Article
Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage
Velalopoulou, Anastasia, Chatterjee, Shampa, Pietrofesa, Ralph A, Koziol-White, Cynthia, Panettieri, Reynold A, Lin, Liyong, Tuttle, Stephen, Berman, Abigail, Koumenis, Constantinos, Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (25.11.2017)
Published in International journal of molecular sciences (25.11.2017)
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Journal Article