Affinity maturation of antibodies assisted by in silico modeling
Barderas, Rodrigo, Desmet, Johan, Timmerman, Peter, Meloen, Rob, Casal, J. Ignacio
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2008)
Get full text
Journal Article
Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity
Wentink, Madelon Q., Hackeng, Tilman M., Tabruyn, Sebastien P., Puijk, Wouter C., Schwamborn, Klaus, Altschuh, Daniele, Meloen, Rob H., Schuurman, Teun, Griffioen, Arjan W., Timmerman, Peter
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2016)
Get full text
Journal Article
Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS™ technology
Timmerman, Peter, Puijk, Wouter C., Meloen, Rob H.
Published in Journal of molecular recognition (01.09.2007)
Published in Journal of molecular recognition (01.09.2007)
Get full text
Journal Article
Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide
Oerlemans, Ruud, Berkers, Celia R., Assaraf, Yehuda G., Scheffer, George L., Peters, Godefridus J., Verbrugge, Sue Ellen, Cloos, Jacqueline, Slootstra, Jerry, Meloen, Rob H., Shoemaker, Robert H., Dijkmans, Ben A. C., Scheper, Rik J., Ovaa, Huib, Jansen, Gerrit
Published in Investigational new drugs (01.10.2018)
Published in Investigational new drugs (01.10.2018)
Get full text
Journal Article
A Combinatorial Approach for the Design of Complementarity-determining Region-derived Peptidomimetics with in Vitro Anti-tumoral Activity
Timmerman, Peter, Barderas, Rodrigo, Desmet, Johan, Altschuh, Danièle, Shochat, Susana, Hollestelle, Martine J., Höppener, Jo W.M., Monasterio, Alberto, Casal, J.Ignacio, Meloen, Rob H.
Published in The Journal of biological chemistry (04.12.2009)
Published in The Journal of biological chemistry (04.12.2009)
Get full text
Journal Article
Novel Rabies Virus-Neutralizing Epitope Recognized by Human Monoclonal Antibody: Fine Mapping and Escape Mutant Analysis
MARISSEN, Wilfred E, ARJEN KRAMER, R, JONGENEELEN, Mandy, THIJSSE, Sandra, THROSBY, Mark, DE KRUIF, John, RUPPRECHT, Charles E, DIETZSCHOLD, Bernhard, GOUDSMIT, Jaap, BAKKER, Alexander B. H, RICE, Amy, WELDON, William C, NIEZGODA, Michael, FABER, Milosz, SLOOTSTRA, Jerry W, MELOEN, Rob H, CLIJSTERS-VAN DER HORST, Marieke, VISSER, Therese J
Published in Journal of Virology (01.04.2005)
Published in Journal of Virology (01.04.2005)
Get full text
Journal Article
Binding of CDR-derived peptides is mechanistically different from that of high-affinity parental antibodies
Timmerman, Peter, Shochat, Susana G., Desmet, Johan, Barderas, Rodrigo, Casal, Jose Ignacio, Meloen, Rob H., Altschuh, Danièle
Published in Journal of molecular recognition (01.11.2010)
Published in Journal of molecular recognition (01.11.2010)
Get full text
Journal Article
Heterologous Stacking of Prion Protein Peptides Reveals Structural Details of Fibrils and Facilitates Complete Inhibition of Fibril Growth
Boshuizen, Ronald S., Schulz, Veronica, Morbin, Michela, Mazzoleni, Giulia, Meloen, Rob H., Langedijk, Johannes P.M.
Published in The Journal of biological chemistry (08.05.2009)
Published in The Journal of biological chemistry (08.05.2009)
Get full text
Journal Article
Identification of an Interleukin-15α Receptor-binding Site on Human Interleukin-15
Bernard, Jérôme, Harb, Catherine, Mortier, Erwan, Quéméner, Agnès, Meloen, Rob H., Vermot-Desroches, Claudine, Wijdeness, John, van Dijken, Peter, Grötzinger, Joachim, Slootstra, Jerry W., Plet, Ariane, Jacques, Yannick
Published in The Journal of biological chemistry (04.06.2004)
Published in The Journal of biological chemistry (04.06.2004)
Get full text
Journal Article
An in vitro screening assay based on synthetic prion protein peptides for identification of fibril-interfering compounds
Boshuizen, Ronald S., Langeveld, Jan P.M., Salmona, Mario, Williams, Alun, Meloen, Rob H., Langedijk, Johannes P.M.
Published in Analytical biochemistry (15.10.2004)
Published in Analytical biochemistry (15.10.2004)
Get full text
Journal Article
Antifungal activity of synthetic peptides derived from Impatiens balsamina antimicrobial peptides Ib-AMP1 and Ib-AMP4
Thevissen, Karin, François, Isabelle E.J.A., Sijtsma, Lolke, Amerongen, Aart van, Schaaper, Wim M.M., Meloen, Rob, Posthuma-Trumpie, Truus, Broekaert, Willem F., Cammue, Bruno P.A.
Published in Peptides (New York, N.Y. : 1980) (01.07.2005)
Published in Peptides (New York, N.Y. : 1980) (01.07.2005)
Get full text
Journal Article
Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat
Adan, Roger A.H, Szklarczyk, Arkadiusz W, Oosterom, Julia, Brakkee, Jan H, Nijenhuis, Wouter A.J, Schaaper, Wim M.M, Meloen, Rob H, Gispen, Willem Hendrik
Published in European journal of pharmacology (13.08.1999)
Published in European journal of pharmacology (13.08.1999)
Get full text
Journal Article
Inactivated recombinant plant virus protects dogs from a lethal challenge with canine parvovirus
Langeveld, Jan P.M, Brennan, Frank R, Martı́nez-Torrecuadrada, Jorge L, Jones, Tim D, Boshuizen, Ronald S, Vela, Carmen, Casal, J.Ignacio, Kamstrup, Søren, Dalsgaard, Kristian, Meloen, Rob H, Bendig, Mary M, Hamilton, William D.O
Published in Vaccine (14.06.2001)
Published in Vaccine (14.06.2001)
Get full text
Journal Article
Peptide transport by the multidrug resistance protein MRP1
DE JONG, Mariska C, SLOOTSTRA, Jerry W, SCHEFFER, George L, SCHROEIJERS, Anouk B, PUIJK, Wouter C, DINKELBERG, Remco, KOOL, Marcel, BROXTERMAN, Henk J, MELOEN, Rob H, SCHEPER, Rik J
Published in Cancer research (Chicago, Ill.) (15.03.2001)
Get full text
Published in Cancer research (Chicago, Ill.) (15.03.2001)
Journal Article
Active immunization against gonadotrophin-releasing hormone in Chinese male pigs: effects of dose on antibody titer, hormone levels and sexual development
Zeng, Xian Y., Turkstra, Johan A., Meloen, Rob H., Liu, Xian Y., Chen, Fa Q., Schaaper, Wim M.M., (Ria) Oonk, H.B., Guo, Da Z., van de Wiel, Dick F.M.
Published in Animal reproduction science (15.04.2002)
Published in Animal reproduction science (15.04.2002)
Get full text
Journal Article
Multidrug-Resistant Tumor Cells Remain Sensitive to a Recombinant Interleukin-4-Pseudomonas Exotoxin, Except When Overexpressing the Multidrug Resistance Protein MRP1
DE JONG, Mariska C, SCHEFFER, George L, SCHEPER, Rik J, BROXTERMAN, Henk J, HOOIJBERG, Jan H, SLOOTSTRA, Jerry W, MELOEN, Rob H, KREITMAN, Robert J, HUSAIN, Syed R, JOSHI, Bharat H, PURI, Raj K
Published in Clinical cancer research (15.10.2003)
Get full text
Published in Clinical cancer research (15.10.2003)
Journal Article
Polyanion induced fibril growth enables the development of a reproducible assay in solution for the screening of fibril interfering compounds, and the investigation of the prion nucleation site
Boshuizen, Ronald S., Morbin, Michela, Mazzoleni, Giulia, Tagliavini, Fabrizio, Meloen, Rob H., Langedijk, Johannes P. M.
Published in Amyloid (2007)
Published in Amyloid (2007)
Get full text
Journal Article