IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice
Mellott, Tiffany J, Pender, Sarah M, Burke, Rebecca M, Langley, Erika A, Blusztajn, Jan Krzysztof
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Perinatal choline supplementation prevents learning and memory deficits and reduces brain amyloid Aβ42 deposition in AppNL-G-F Alzheimer's disease model mice
Bellio, Thomas A, Laguna-Torres, Jessenia Y, Campion, Mary S, Chou, Jay, Yee, Sheila, Blusztajn, Jan K, Mellott, Tiffany J
Published in PloS one (05.02.2024)
Published in PloS one (05.02.2024)
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Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice
Mellott, Tiffany J, Huleatt, Olivia M, Shade, Bethany N, Pender, Sarah M, Liu, Yi B, Slack, Barbara E, Blusztajn, Jan K
Published in PloS one (19.01.2017)
Published in PloS one (19.01.2017)
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High maternal choline consumption during pregnancy and nursing alleviates deficits in social interaction and improves anxiety-like behaviors in the BTBR T+Itpr3tf/J mouse model of autism
Langley, Erika A., Krykbaeva, Marina, Blusztajn, Jan Krzysztof, Mellott, Tiffany J.
Published in Behavioural brain research (01.02.2015)
Published in Behavioural brain research (01.02.2015)
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Gestational Choline Supply Regulates Methylation of Histone H3, Expression of Histone Methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA Methylation of Their Genes in Rat Fetal Liver and Brain
Davison, Jessica M., Mellott, Tiffany J., Kovacheva, Vesela P., Blusztajn, Jan Krzysztof
Published in The Journal of biological chemistry (23.01.2009)
Published in The Journal of biological chemistry (23.01.2009)
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A Narrative Review on Maternal Choline Intake and Liver Function of the Fetus and the Infant; Implications for Research, Policy, and Practice
Obeid, Rima, Schön, Christiane, Derbyshire, Emma, Jiang, Xinyin, Mellott, Tiffany J, Blusztajn, Jan Krzysztof, Zeisel, Steven H
Published in Nutrients (01.01.2024)
Published in Nutrients (01.01.2024)
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Gestational Choline Deficiency Causes Global and Igf2 Gene DNA Hypermethylation by Up-regulation of Dnmt1 Expression
Kovacheva, Vesela P., Mellott, Tiffany J., Davison, Jessica M., Wagner, Nicholas, Lopez-Coviella, Ignacio, Schnitzler, Aletta C., Blusztajn, Jan K.
Published in The Journal of biological chemistry (26.10.2007)
Published in The Journal of biological chemistry (26.10.2007)
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Neuroprotective actions of perinatal choline nutrition
Blusztajn, Jan Krzysztof, Mellott, Tiffany J
Published in Clinical chemistry and laboratory medicine (01.03.2013)
Published in Clinical chemistry and laboratory medicine (01.03.2013)
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Journal Article
BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer’s disease
Burke, Rebecca M., Norman, Timothy A., Haydar, Tarik F., Slack, Barbara E., Leeman, Susan E., Blusztajn, Jan Krzysztof, Mellott, Tiffany J.
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
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Cerebral Gray and White Matter Monogalactosyl Diglyceride Levels Rise with the Progression of Alzheimer's Disease
Blusztajn, Jan Krzysztof, Aytan, Nurgul, Rajendiran, Thekkelnaycke, Mellott, Tiffany J, Soni, Tanu, Burant, Charles F, Serrano, Geidy E, Beach, Thomas G, Lin, Honghuang, Stein, Thor D
Published in Journal of Alzheimer's disease (01.01.2023)
Published in Journal of Alzheimer's disease (01.01.2023)
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Correction: Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice
Mellott, Tiffany J, Huleatt, Olivia M, Shade, Bethany N, Pender, Sarah M, Liu, Yi B, Slack, Barbara E, Blusztajn, Jan K
Published in PloS one (23.03.2017)
Published in PloS one (23.03.2017)
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Prenatal choline supplementation in rats increases the expression of IGF2 and its receptor IGF2R and enhances IGF2-induced acetylcholine release in hippocampus and frontal cortex
Napoli, Isabella, Blusztajn, Jan Krzysztof, Mellott, Tiffany J
Published in Brain research (27.10.2008)
Published in Brain research (27.10.2008)
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BMP9 protects septal neurons from axotomy-evoked loss of cholinergic phenotype
Lopez-Coviella, Ignacio, Mellott, Tiffany J, Schnitzler, Aletta C, Blusztajn, Jan K
Published in PloS one (13.06.2011)
Published in PloS one (13.06.2011)
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Immunohistochemical Analysis of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) Expression in the Rat and Human Hippocampus: Decline in CA3 During Progression of Alzheimer's Disease
Adams, Stephanie L, Benayoun, Laurent, Tilton, Kathy, Mellott, Tiffany J, Seshadri, Sudha, Blusztajn, Jan Krzysztof, Delalle, Ivana
Published in Journal of Alzheimer's disease (01.01.2018)
Published in Journal of Alzheimer's disease (01.01.2018)
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Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats
Glenn, Melissa J., Gibson, Erin M., Kirby, Elizabeth D., Mellott, Tiffany J., Blusztajn, Jan K., Williams, Christina L.
Published in The European journal of neuroscience (01.04.2007)
Published in The European journal of neuroscience (01.04.2007)
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Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats
Glenn, Melissa J, Kirby, Elizabeth D, Gibson, Erin M, Wong-Goodrich, Sarah J, Mellott, Tiffany J, Blusztajn, Jan K, Williams, Christina L
Published in Brain research (27.10.2008)
Published in Brain research (27.10.2008)
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Journal Article
Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival
Kovacheva, Vesela P, Davison, Jessica M, Mellott, Tiffany J, Rogers, Adrianne E, Yang, Shi, O'Brien, Michael J, Blusztajn, Jan Krzysztof
Published in The FASEB journal (01.04.2009)
Published in The FASEB journal (01.04.2009)
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