The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, Schistocerca gregaria
Luck, Victoria L., Richards, David P., Shaikh, Ashif Y., Franzyk, Henrik, Mellor, Ian R.
Published in Molecules (Basel, Switzerland) (19.11.2021)
Published in Molecules (Basel, Switzerland) (19.11.2021)
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Journal Article
Transgenic Enrichment of Cardiomyocytes From Human Embryonic Stem Cells
Anderson, David, Self, Tim, Mellor, Ian R, Goh, Gareth, Hill, Stephen J, Denning, Chris
Published in Molecular therapy (01.11.2007)
Published in Molecular therapy (01.11.2007)
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Journal Article
Philanthotoxin-343 attenuates retinal and optic nerve injury, and protects visual function in rats with N-methyl-D-aspartate-induced excitotoxicity
Fazel, Muhammad Fattah, Abu, Izuddin Fahmy, Mohamad, Mohamad Haiqal Nizar, Agarwal, Renu, Iezhitsa, Igor, Bakar, Nor Salmah, Juliana, Norsham, Mellor, Ian R, Franzyk, Henrik
Published in PloS one (24.07.2020)
Published in PloS one (24.07.2020)
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Journal Article
Characterisation of chlorinated, brominated and mixed halogenated dioxins, furans and biphenyls as potent and as partial agonists of the Aryl hydrocarbon receptor
Wall, Richard J., Fernandes, Alwyn, Rose, Martin, Bell, David R., Mellor, Ian R.
Published in Environment international (01.03.2015)
Published in Environment international (01.03.2015)
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Journal Article
(−)-Adaline from the Adalia Genus of Ladybirds Is a Potent Antagonist of Insect and Specific Mammalian Nicotinic Acetylcholine Receptors
Richards, David P., Patel, Rohit N., Duce, Ian R., Khambay, Bhupinder P. S., Birkett, Michael A., Pickett, John A., Mellor, Ian R.
Published in Molecules (Basel, Switzerland) (20.10.2022)
Published in Molecules (Basel, Switzerland) (20.10.2022)
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Journal Article
Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress
Mohamad, Mohamad Haiqal Nizar, Abu, Izuddin Fahmy, Fazel, Muhammad Fattah, Agarwal, Renu, Iezhitsa, Igor, Juliana, Norsham, Mellor, Ian R, Franzyk, Henrik
Published in Frontiers in pharmacology (14.12.2021)
Published in Frontiers in pharmacology (14.12.2021)
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Acai Berry ( Euterpe sp.) Extracts Are Neuroprotective against L-Glutamate-Induced Toxicity by Limiting Mitochondrial Dysfunction and Cellular Redox Stress
ALNasser, Maryam N, AlSaadi, Ayman M, Whitby, Alison, Kim, Dong-Hyun, Mellor, Ian R, Carter, Wayne G
Published in Life (Basel, Switzerland) (01.04.2023)
Published in Life (Basel, Switzerland) (01.04.2023)
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Journal Article
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease
Furutani, Shogo, Ihara, Makoto, Lees, Kristin, Buckingham, Steven D., Partridge, Frederick A., David, Jonathan A., Patel, Rohit, Warchal, Scott, Mellor, Ian R., Matsuda, Kazuhiko, Sattelle, David B.
Published in International journal for parasitology -- drugs and drug resistance (01.08.2018)
Published in International journal for parasitology -- drugs and drug resistance (01.08.2018)
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Journal Article
Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease
Rosini, Michela, Simoni, Elena, Caporaso, Roberta, Basagni, Filippo, Catanzaro, Michele, Abu, Izuddin F., Fagiani, Francesca, Fusco, Federica, Masuzzo, Sara, Albani, Diego, Lanni, Cristina, Mellor, Ian R., Minarini, Anna
Published in European journal of medicinal chemistry (15.10.2019)
Published in European journal of medicinal chemistry (15.10.2019)
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Journal Article
Damaging coding variants within kainate receptor channel genes are enriched in individuals with schizophrenia, autism and intellectual disabilities
Koromina, Maria, Flitton, Miles, Blockley, Alix, Mellor, Ian R., Knight, Helen M.
Published in Scientific reports (16.12.2019)
Published in Scientific reports (16.12.2019)
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Journal Article
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties
Basagni, Filippo, Ortega, Jose A., Bertozzi, Sine M., Armirotti, Andrea, Summa, Maria, Bertorelli, Rosalia, Bartolini, Manuela, Mellor, Ian R., Bedeschi, Martina, Bottegoni, Giovanni, Lembo, Vittorio, Minarini, Anna, Cavalli, Andrea, Rosini, Michela
Published in European journal of medicinal chemistry (05.12.2023)
Published in European journal of medicinal chemistry (05.12.2023)
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Journal Article
Non-canonical endogenous expression of voltage-gated sodium channel Na V 1.7 subtype by the TE671 rhabdomyosarcoma cell line
Ngum, Neville M, Aziz, Muhammad Y A, Mohammed Latif, Liaque, Wall, Richard J, Duce, Ian R, Mellor, Ian R
Published in The Journal of physiology (01.05.2022)
Published in The Journal of physiology (01.05.2022)
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Journal Article
Inhibition of Acetylcholinesterase, β-Amyloid Aggregation, and NMDA Receptors in Alzheimer’s Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush
Rosini, Michela, Simoni, Elena, Bartolini, Manuela, Cavalli, Andrea, Ceccarini, Luisa, Pascu, Nicoleta, McClymont, David W, Tarozzi, Andrea, Bolognesi, Maria L, Minarini, Anna, Tumiatti, Vincenzo, Andrisano, Vincenza, Mellor, Ian R, Melchiorre, Carlo
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
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Journal Article
Non‐canonical endogenous expression of voltage‐gated sodium channel NaV1.7 subtype by the TE671 rhabdomyosarcoma cell line
Ngum, Neville M., Aziz, Muhammad Y. A., Mohammed Latif, Liaque, Wall, Richard J., Duce, Ian R., Mellor, Ian R.
Published in The Journal of physiology (01.05.2022)
Published in The Journal of physiology (01.05.2022)
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Journal Article
A kainate receptor GluK4 deletion, protective against bipolar disorder, is associated with enhanced cognitive performance across diagnoses in the TwinsUK cohort
Koromina, Maria, Flitton, Miles, Mellor, Ian R., Knight, Helen Miranda
Published in The world journal of biological psychiatry (28.05.2019)
Published in The world journal of biological psychiatry (28.05.2019)
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