The origins and genetic interactions of KRAS mutations are allele- and tissue-specific
Cook, Joshua H., Melloni, Giorgio E. M., Gulhan, Doga C., Park, Peter J., Haigis, Kevin M.
Published in Nature communications (22.03.2021)
Published in Nature communications (22.03.2021)
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A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data
Melloni, Giorgio E M, Mazzarella, Luca, Bernard, Loris, Bodini, Margherita, Russo, Anna, Luzi, Lucilla, Pelicci, Pier Giuseppe, Riva, Laura
Published in Breast cancer research : BCR (31.05.2017)
Published in Breast cancer research : BCR (31.05.2017)
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Journal Article
Computational analysis of cancer genome sequencing data
Cortés-Ciriano, Isidro, Gulhan, Doga C., Lee, Jake June-Koo, Melloni, Giorgio E. M., Park, Peter J.
Published in Nature reviews. Genetics (01.05.2022)
Published in Nature reviews. Genetics (01.05.2022)
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Journal Article
Association of Apolipoprotein B-Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis: Distinguishing Between Particle Concentration, Type, and Content
Marston, Nicholas A, Giugliano, Robert P, Melloni, Giorgio E M, Park, Jeong-Gun, Morrill, Valerie, Blazing, Michael A, Ference, Brian, Stein, Evan, Stroes, Erik S, Braunwald, Eugene, Ellinor, Patrick T, Lubitz, Steven A, Ruff, Christian T, Sabatine, Marc S
Published in JAMA cardiology (01.03.2022)
Published in JAMA cardiology (01.03.2022)
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Clonal hematopoiesis, cardiovascular events and treatment benefit in 63,700 individuals from five TIMI randomized trials
Marston, Nicholas A., Pirruccello, James P., Melloni, Giorgio E. M., Kamanu, Frederick, Bonaca, Marc P., Giugliano, Robert P., Scirica, Benjamin M., Wiviott, Stephen D., Bhatt, Deepak L., Steg, Philippe Gabriel, Raz, Itamar, Braunwald, Eugene, Libby, Peter, Ellinor, Patrick T., Bick, Alexander G., Sabatine, Marc S., Ruff, Christian T.
Published in Nature medicine (01.09.2024)
Published in Nature medicine (01.09.2024)
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Journal Article
INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments
de Pretis, Stefano, Kress, Theresia, Morelli, Marco J, Melloni, Giorgio E M, Riva, Laura, Amati, Bruno, Pelizzola, Mattia
Published in Bioinformatics (01.09.2015)
Published in Bioinformatics (01.09.2015)
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Journal Article
Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention
Marston, Nicholas A, Pirruccello, James P, Melloni, Giorgio E M, Koyama, Satoshi, Kamanu, Frederick K, Weng, Lu-Chen, Roselli, Carolina, Kamatani, Yoichiro, Komuro, Issei, Aragam, Krishna G, Butterworth, Adam S, Ito, Kaoru, Lubitz, Steve A, Ellinor, Patrick T, Sabatine, Marc S, Ruff, Christian T
Published in JAMA cardiology (01.02.2023)
Published in JAMA cardiology (01.02.2023)
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Journal Article
Mutations targeting the coagulation pathway are enriched in brain metastases
Richichi, Cristina, Fornasari, Lorenzo, Melloni, Giorgio E. M., Brescia, Paola, Patanè, Monica, Del Bene, Massimiliano, Mustafa, Dana A. M., Kros, Johan M., Pollo, Bianca, Pruneri, Giancarlo, Sciandivasci, Angela, Munzone, Elisabetta, DiMeco, Francesco, Pelicci, Pier Giuseppe, Riva, Laura, Pelicci, Giuliana
Published in Scientific reports (26.07.2017)
Published in Scientific reports (26.07.2017)
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Journal Article
Novel Polygenic Risk Score and Established Clinical Risk Factors for Risk Estimation of Aortic Stenosis
Small, Aeron M, Melloni, Giorgio E M, Kamanu, Frederick K, Bergmark, Brian A, Bonaca, Marc P, O'Donoghue, Michelle L, Giugliano, Robert P, Scirica, Benjamin M, Bhatt, Deepak, Antman, Elliott M, Raz, Itamar, Wiviott, Stephen D, Truong, Buu, Wilson, Peter W F, Cho, Kelly, O'Donnell, Christopher J, Braunwald, Eugene, Lubitz, Steve A, Ellinor, Patrick, Peloso, Gina M, Ruff, Christian T, Sabatine, Marc S, Natarajan, Pradeep, Marston, Nicholas A
Published in JAMA cardiology (01.04.2024)
Published in JAMA cardiology (01.04.2024)
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Journal Article
Very low-depth whole-genome sequencing in complex trait association studies
Gilly, Arthur, Southam, Lorraine, Suveges, Daniel, Kuchenbaecker, Karoline, Moore, Rachel, Melloni, Giorgio E M, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Ritchie, Graham, Schwartzentruber, Jeremy, Danecek, Petr, Kilian, Britt, Pollard, Martin O, Ge, Xiangyu, Tsafantakis, Emmanouil, Dedoussis, George, Zeggini, Eleftheria
Published in Bioinformatics (01.08.2019)
Published in Bioinformatics (01.08.2019)
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Journal Article
The Effect of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition on the Risk of Venous Thromboembolism
Marston, Nicholas A., Gurmu, Yared, Melloni, Giorgio E.M., Bonaca, Marc, Gencer, Baris, Sever, Peter S., Pedersen, Terje R., Keech, Anthony C., Roselli, Carolina, Lubitz, Steven A., Ellinor, Patrick T., O’Donoghue, Michelle L., Giugliano, Robert P., Ruff, Christian T., Sabatine, Marc S.
Published in Circulation (New York, N.Y.) (19.05.2020)
Published in Circulation (New York, N.Y.) (19.05.2020)
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Journal Article
Per-Particle Cardiovascular Risk of Lipoprotein(a) vs Non-Lp(a) Apolipoprotein B-Containing Lipoproteins
Marston, Nicholas A., Melloni, Giorgio E.M., Murphy, Sabina A., Morze, Jakub, Kamanu, Frederick K., Ellinor, Patrick T., Ruff, Christian T., Sabatine, Marc S.
Published in Journal of the American College of Cardiology (23.01.2024)
Published in Journal of the American College of Cardiology (23.01.2024)
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Journal Article
Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns
Watson, Emma V., Lee, Jake June-Koo, Gulhan, Doga C., Melloni, Giorgio E. M., Venev, Sergey V., Magesh, Rayna Y., Frederick, Abdulrazak, Chiba, Kunitoshi, Wooten, Eric C., Naxerova, Kamila, Dekker, Job, Park, Peter J., Elledge, Stephen J.
Published in Nature genetics (01.05.2024)
Published in Nature genetics (01.05.2024)
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Journal Article
Blood gas analyses in hyperbaric and underwater environments: a systematic review
Paganini, Matteo, Moon, Richard E, Boccalon, Nicole, Melloni, Giorgio E M, Giacon, Tommaso A, Camporesi, Enrico M, Bosco, Gerardo
Published in Journal of applied physiology (1985) (01.02.2022)
Published in Journal of applied physiology (1985) (01.02.2022)
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Journal Article
Risk of new‐onset diabetes and efficacy of pharmacological weight loss therapy
Moura, Filipe A., Bellavia, Andrea, Berg, David D., Melloni, Giorgio E. M., Feinberg, Mark W., Leiter, Lawrence A., Bohula, Erin A., Morrow, David A., Scirica, Benjamin A., Wiviott, Stephen D., Sabatine, Marc S.
Published in Diabetes, obesity & metabolism (01.10.2024)
Published in Diabetes, obesity & metabolism (01.10.2024)
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Journal Article
Application of the Win Ratio Method in the ENGAGE AF-TIMI 48 Trial Comparing Edoxaban With Warfarin in Patients With Atrial Fibrillation
Bergmark, Brian A, Park, Jeong-Gun, Hamershock, Rose A, Melloni, Giorgio E M, De Caterina, Raffaele, Antman, Elliott M, Ruff, Christian T, Rutman, Howard, Mercuri, Michele F, Lanz, Hans-Joachim, Braunwald, Eugene, Giugliano, Robert P
Published in Circulation Cardiovascular quality and outcomes (01.07.2024)
Published in Circulation Cardiovascular quality and outcomes (01.07.2024)
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Journal Article
LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer
Melloni, Giorgio E M, de Pretis, Stefano, Riva, Laura, Pelizzola, Mattia, Céol, Arnaud, Costanza, Jole, Müller, Heiko, Zammataro, Luca
Published in BMC bioinformatics (09.02.2016)
Published in BMC bioinformatics (09.02.2016)
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