Comparative biochemical kinase activity analysis identifies rivoceranib as a highly selective VEGFR2 inhibitor
Jang, Seong, Strickland, Bill, Finis, Lynda, Kooijman, Jeffrey J., Melis, Janneke J. T. M., Zaman, Guido J. R., Van Tornout, Jan
Published in Cancer chemotherapy and pharmacology (01.06.2023)
Published in Cancer chemotherapy and pharmacology (01.06.2023)
Get full text
Journal Article
Abstract 2145: High SLFN11 expression correlates with sensitivity to lurbinectedin in small cell lung cancer (SCLC) models
Gupta, Aparna, Vaidya, Kedar S., Melis, Janneke J.T.M., Hauptschein, Robert, Brock, Graham, Humphreys, Robin
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Abstract A100: Large-scale cell line profiling of small molecule MAPK pathway inhibitors identifies important differences between therapeutics acting on the same biochemical target
Kooijman, Jeffrey J., Koerdi, Awan Al, van Riel, Wilhelmina E., Bossche, Esmee van den, Dylus, Jelle, de Roos, Jeroen A.D.M., Melis, Janneke J.T.M., Zaman, Guido J.R.
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
Get full text
Journal Article
Abstract B061: Sensitivity and resistance mechanisms of human cancer cell lines treated with PARP, POLθ, and ATR inhibitor combinations in 2D and 3D spheroid cell viability assays
Melis, Janneke J.T.M., Kooijman, Jeffrey, Wetemans, Sabine, Geerdink-Datema, Suzan, Dylus, Jelle, de Roos, Jeroen A.D.M., van Riel, Wilhelmina E., Zaman, Guido J.R.
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
Get full text
Journal Article
Comparative kinase and cancer cell panel profiling of kinase inhibitors approved for clinical use from 2018 to 2020
Kooijman, Jeffrey J, van Riel, Wilhelmina E, Dylus, Jelle, Prinsen, Martine B W, Grobben, Yvonne, de Bitter, Tessa J J, van Doornmalen, Antoon M, Melis, Janneke J T M, Uitdehaag, Joost C M, Narumi, Yugo, Kawase, Yusuke, de Roos, Jeroen A D M, Willemsen-Seegers, Nicole, Zaman, Guido J R
Published in Frontiers in oncology (14.09.2022)
Published in Frontiers in oncology (14.09.2022)
Get full text
Journal Article