Selection of extreme phenotypes: the role of clinical observation in translational research
Pérez-Gracia, José Luis, Gúrpide, Alfonso, Ruiz-Ilundain, María Gloria, Alegría, Carlos Alfaro, Colomer, Ramon, García-Foncillas, Jesús, Melero Bermejo, Ignacio
Published in Clinical & translational oncology (01.03.2010)
Published in Clinical & translational oncology (01.03.2010)
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Journal Article
ATHENA: A phase 1/2 study of AZD5851, a chimeric antigen receptor (CAR) T-cell therapy directed against GPC3 in adult patients with advanced/recurrent hepatocellular carcinoma (HCC)
Hamilton, Ashley, Kelley, Robin Kate, Li, Daneng, Melero Bermejo, Ignacio, Abou-Alfa, Ghassan K., Alese, Olatunji B., Al-Rajabi, Raed Moh'd Taiseer, Babiker, Hani M., Borad, Mitesh, Dayyani, Farshid, Gutierrez, Martin, Hong, Jung Yong, Kankeu Fonkoua, Lionel Aurelien, Karasic, Thomas Benjamin, Kardosh, Adel, Keenan, Bridget P., Noonan, Anne M., Saeed, Anwaar, Bondanza, Attilio, Stone, John
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
Initial results from the phase 2A trial of visugromab (CTL-002) + nivolumab in advanced/metastatic anti-PD1/-L1 relapsed/refractory solid tumors (The GDFATHER-TRIAL)
Melero Bermejo, Ignacio, de Miguel, Maria J., Alonso, Guzman, Ramelyte, Egle, Joerger, Markus, Sayehli, Cyrus, Gromke, Tanja, De Velasco, Guillermo, Martin Liberal, Juan, Garralda, Elena, Rodriguez-Ruiz, Maria E., Calvo, Emiliano, Dummer, Reinhard, Hess, Dagmar, Goebeler, Maria-Elisabeth, Schuler, Martin H., Fettes, Petra, Klar, Kathrin, Hermann, Frank, Leo, Eugen
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Whole exome sequencing and machine learning germline analysis of individuals presenting with phenotypes of extreme high and low risk of developing tobacco-induced lung adenocarcinoma
Perez-Gracia, Jose Luis, Guruceaga, Elisabet, Andueza, Maria Pilar, Ocon, Marimar, de VIllalonga Zornoza, Nicolas, Fodop Sokoudjou, Jafait Junior, Alkorta-Aranburu, Gorka, Camps, Carlos, Jantus-Lewintre, Eloisa, Navamuel Andueza, Maria, Sanmamed, Miguel F., Gurpide, Alfonso, Melero Bermejo, Ignacio, Elgendy, Mohamed, Perez Valencia, Juan Alberto, Hernaez, Mikel, Pio Oses, Ruben, Montuenga, Luis M., Ochoa, Idoia, Patiño-García, Ana
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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A phase 1 dose-escalation study to investigate the safety, efficacy, pharmacokinetics, and pharmacodynamic activity of cln-619 (Anti-MICA/B antibody) alone and in combination with pembrolizumab in patients with advanced solid tumors
Wang, Judy S., Gutierrez, Martin, Rasco, Drew W., Melero Bermejo, Ignacio, Powderly, John D., Hamilton, Erika P., Millward, Michael, Arance, Ana Maria, Stec, Rafal, Moreno, Victor, Sharma, Manish, Lugowska, Iwona A., Shackleton, Mark J., Frentzas, Sophia, Janik, John Edward, Liu, Tracy, Shapiro, Irina, Whalen, Kerry, Jones, Jeffrey Alan, Spira, Alexander I.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs
Weeratunga, Praveen, Denney, Laura, Bull, Joshua A., Repapi, Emmanouela, Sergeant, Martin, Etherington, Rachel, Vuppussetty, Chaitanya, Turner, Gareth D. H., Clelland, Colin, Woo, Jeongmin, Cross, Amy, Issa, Fadi, de Andrea, Carlos Eduardo, Melero Bermejo, Ignacio, Sims, David, McGowan, Simon, Zurke, Yasemin-Xiomara, Ahern, David J., Gamez, Eddie C., Whalley, Justin, Richards, Duncan, Klenerman, Paul, Monaco, Claudia, Udalova, Irina A., Dong, Tao, Antanaviciute, Agne, Ogg, Graham, Knight, Julian C., Byrne, Helen M., Taylor, Stephen, Ho, Ling-Pei
Published in Nature communications (08.11.2023)
Published in Nature communications (08.11.2023)
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Journal Article
Serum interleukin 8 (IL-8) may serve as a biomarker of response to immuno-oncology (I-O) therapy
Carleton, Michael, Zhou, Ming, De Henau, Olivier, Phillips, Penny, Chen, Tian, Feng, Ye, Huang, Shu-Pang, Walsh, Alice, Reilly, Timothy P., Melero Bermejo, Ignacio
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Phase 1b/2 study of nivolumab in combination with an anti–IL-8 monoclonal antibody, BMS-986253, in a biomarker-enriched population of patients with advanced cancer
Melero Bermejo, Ignacio, Jaffee, Elizabeth M., Davar, Diwakar, Cardarelli, Josephine, Williams, Daphne, Phillips, Penny, Carleton, Michael, Zhou, Ming, De Henau, Olivier, Monga, Manish, Drake, Charles G.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Phase II study SECOMBIT (sequential combo immuno and target therapy study): A subgroup analysis with a longer follow-up
Ascierto, Paolo Antonio, Mandalà, Mario, Ferrucci, Pier Francesco, Guidoboni, Massimo, Rutkowski, Piotr, Ferraresi, Virginia, Arance, Ana Maria, Guida, Michele, Maiello, Evaristo, Gogas, Helen, Richtig, Erika, Fierro, Maria Teresa, Lebbe, Celeste, Helgadottir, Hildur, Melero Bermejo, Ignacio, Palmieri, Giuseppe, Giannarelli, Diana, Grimaldi, Antonio Maria, Dummer, Reinhard, Chiarion-Sileni, Vanna
Published in JOURNAL OF CLINICAL ONCOLOGY (01.06.2022)
Published in JOURNAL OF CLINICAL ONCOLOGY (01.06.2022)
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Conference Proceeding
Whole exome sequencing of germline DNA of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung adenocarcinoma (LUAD) according to KRAS status
Perez-Gracia, Jose Luis, Pita, Guillermo, Segura, Victor, Pajares, Maria Jose, Fusco, Juan Pablo, Andueza, Maria Pilar, Sanchez-Bayona, Rodrigo, Guruceaga, Elisabet, Mora, Maria Isabel, Gurpide, Alfonso, de Torres Tajes, Juan Pablo, Zulueta, Javier, Pio Oses, Ruben, Melero Bermejo, Ignacio, Sanmamed, Miguel F., Rodriguez-Ruiz, Maria E., De Andrea, Carlos E, Montuenga, Luis M., Gonzalez-Neira, Anna, Patiño-García, Ana
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Safety, PK/PD, and anti-tumor activity of RO6874281, an engineered variant of interleukin-2 (IL-2v) targeted to tumor-associated fibroblasts via binding to fibroblast activation protein (FAP)
Soerensen, Morten Mau, Ros, Willeke, Rodriguez-Ruiz, Maria E., Robbrecht, Debbie, Rohrberg, Kristoffer Staal, Martin-Liberal, Juan, Lassen, Ulrik Niels, Melero Bermejo, Ignacio, Lolkema, Martijn P., Tabernero, Josep, Boetsch, Christophe, Piper-Lepoutre, Hanna, Waldhauer, Inja, Charo, Jehad, Evers, Stefan, Teichgräber, Volker, Schellens, Jan H. M.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
COMPOSITIONS FOR INTRATUMORAL ADMINISTRATION AND RELATED METHODS
MELERO BERMEJO, Ignacio, ALVAREZ RODRIGUEZ, Maite, QUINTERO ORTIZ, Marisol
Year of Publication 06.10.2022
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Year of Publication 06.10.2022
Patent
NEW CONJUGATES AND COMPOSITIONS FOR IMMUNOTHERAPY AND ANTITUMORAL TREATMENT
BULFONE-PAUS, SILVIA, DUITMAN, ERWIN, BERRAONDO LOPEZ, PEDRO, MELERO BERMEJO, IGNACIO JAVIER, PALAZON GARCIA, FRANCISCO DE ASIS, OCHOA NIETO, MARIA DEL CARMEN, FIORAVANTI, JESSICA, MEDINA ECHEVERZ, JOSE
Year of Publication 03.04.2018
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Year of Publication 03.04.2018
Patent
New conjugates and compositions for immunotherapy and anti-tumoral treatment
BULFONE-PAUS, SILVIA, DUITMAN, ERWIN HANS, BERRAONDO LOPEZ, PEDRO, MELERO BERMEJO, IGNACIO JAVIER, PALAZON GARCIA, FRANCISCO DE ASIS, OCHOA NIETO, MARIA DEL CARMEN, FIORAVANTI, JESSICA, MEDINA ECHEVERZ, JOSE
Year of Publication 14.07.2016
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Year of Publication 14.07.2016
Patent
Novel conjugates and compositions for immunotherapy and antineoplastic treatment
BULFONE-PAUS SILVIA, MELERO BERMEJO IGNACIO JAVIER, PALAZ N GARCIA FRANCISCO DE ASIS, DUITMAN ERWIN HANS, MEDINA ECHEVERZ JOSE, OCHOA NIETO MARIA DEL CARMEN, BERRAONDO LOPEZ PEDRO, FIORAVANTI JESSICA
Year of Publication 20.05.2015
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Year of Publication 20.05.2015
Patent
COMPOSICION FARMACEUTICA PARA EL TRATAMIENTO DE CANCER
HERVAS STUBBS, SANDRA, MELERO BERMEJO, IGNACIO JAVIER, LE BON, AGNES LAURENCE, DUBROT ARMENDARIZ, JUAN
Year of Publication 24.01.2011
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Year of Publication 24.01.2011
Patent
Compositions comprising apolipoprotein A polypeptide and interleukin 15, and methods of treatment using the same
BULFONE-PAUS SILVIA, DUITMANN ERWIN HANS, PALAZON GARCIA FRANCISCO DE ASIS, MELERO BERMEJO IGNACIO JAVIER, MEDINA ECHEVERZ JOSE, OCHOA NIETO MARIA DEL CARMEN, BERRAONDO LOPEZ PEDRO, FIORAVANTI JESSICA
Year of Publication 08.07.2014
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Year of Publication 08.07.2014
Patent
PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT
HERVAS STUBBS, SANDRA, MELERO BERMEJO, IGNACIO JAVIER, LE BON, AGNES LAURENCE, DUBROT ARMENDARIZ, JUAN
Year of Publication 01.09.2010
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Year of Publication 01.09.2010
Patent
CONJUGATES AND COMPOSITIONS FOR IMMUNOTHERAPY AND ANTI-TUMORAL TREATMENT
BULFONE-PAUS, SILVIA, BERRAONDO LOPEZ, PEDRO, MELERO BERMEJO, IGNACIO JAVIER, OCHOA NIETO, MARIA DEL CARMEN, PALAZ0N GARCIA, FRANCISCO DE ASIS, FIORAVANTI, JESSICA, MEDINA ECHEVERZ, JOSE, DUITMAN, ERWIN, HANS
Year of Publication 26.02.2014
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Year of Publication 26.02.2014
Patent