The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain
Moy, Jamie K, Khoutorsky, Arkady, Asiedu, Marina N, Black, Bryan J, Kuhn, Jasper L, Barragán-Iglesias, Paulino, Megat, Salim, Burton, Michael D, Burgos-Vega, Carolina C, Melemedjian, Ohannes K, Boitano, Scott, Vagner, Josef, Gkogkas, Christos G, Pancrazio, Joseph J, Mogil, Jeffrey S, Dussor, Gregory, Sonenberg, Nahum, Price, Theodore J
Published in The Journal of neuroscience (02.08.2017)
Published in The Journal of neuroscience (02.08.2017)
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Journal Article
IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex
Melemedjian, Ohannes K, Asiedu, Marina N, Tillu, Dipti V, Peebles, Katherine A, Yan, Jin, Ertz, Natalie, Dussor, Gregory O, Price, Theodore J
Published in The Journal of neuroscience (10.11.2010)
Published in The Journal of neuroscience (10.11.2010)
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Journal Article
Resveratrol Engages AMPK to Attenuate ERK and mTOR Signaling in Sensory Neurons and Inhibits Incision-Induced Acute and Chronic Pain
Tillu, Dipti V, Melemedjian, Ohannes K, Asiedu, Marina N, Qu, Ning, De Felice, Milena, Dussor, Gregory, Price, Theodore J
Published in Molecular pain (23.01.2012)
Published in Molecular pain (23.01.2012)
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Journal Article
Targeting Adenosine Monophosphate-Activated Protein Kinase (AMPK) in Preclinical Models Reveals a Potential Mechanism for the Treatment of Neuropathic Pain
Melemedjian, Ohannes K, Asiedu, Marina N, Tillu, Dipti V, Sanoja, Raul, Yan, Jin, Lark, Arianna, Khoutorsky, Arkady, Johnson, Jessica, Peebles, Katherine A, Lepow, Talya, Sonenberg, Nahum, Dussor, Gregory, Price, Theodore J
Published in Molecular pain (21.09.2011)
Published in Molecular pain (21.09.2011)
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Journal Article
Targeting metabolic pathways alleviates bortezomib-induced neuropathic pain without compromising anticancer efficacy in a sex-specific manner
Kuppusamy, Panjamurthy, Haque, Md Mamunul, Traub, Richard J, Melemedjian, Ohannes K
Published in Frontiers in pain research (Lausanne, Switzerland) (24.06.2024)
Published in Frontiers in pain research (Lausanne, Switzerland) (24.06.2024)
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Journal Article
Vascularization of the Dorsal Root Ganglia and Peripheral Nerve of the Mouse: Implications for Chemical-Induced Peripheral Sensory Neuropathies
Jimenez-Andrade, Juan M, Herrera, Monica B, Ghilardi, Joseph R, Vardanyan, Marina, Melemedjian, Ohannes K, Mantyh, Patrick W
Published in Molecular pain (19.03.2008)
Published in Molecular pain (19.03.2008)
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Journal Article
Forced swim stress exacerbates inflammation-induced hyperalgesia and oxidative stress in the rat trigeminal ganglia
Ro, Jin Y, Zhang, Youping, Asgar, Jamila, Shou, Huizhong, Chung, Man-Kyo, Melemedjian, Ohannes K, Da Silva, Joyce T, Chen, Shou
Published in Frontiers in pain research (Lausanne, Switzerland) (24.04.2024)
Published in Frontiers in pain research (Lausanne, Switzerland) (24.04.2024)
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Journal Article
The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth
Wilson, Sarah M, Moutal, Aubin, Melemedjian, Ohannes K, Wang, Yuying, Ju, Weina, François-Moutal, Liberty, Khanna, May, Khanna, Rajesh
Published in Frontiers in cellular neuroscience (24.07.2014)
Published in Frontiers in cellular neuroscience (24.07.2014)
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Journal Article
Disruption of mitochondrial pyruvate oxidation in dorsal root ganglia drives persistent nociceptive sensitization and causes pervasive transcriptomic alterations
Haque, Md Mamunul, Kuppusamy, Panjamurthy, Melemedjian, Ohannes K
Published in Pain (Amsterdam) (01.07.2024)
Published in Pain (Amsterdam) (01.07.2024)
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Journal Article
Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist
Vardanyan, Marina, Melemedjian, Ohannes K., Price, Theodore J., Ossipov, Michael H., Lai, Josephine, Roberts, Ed, Boos, Terrence L., Deschamps, Jeffrey R., Jacobson, Arthur E., Rice, Kenner C., Porreca, Frank
Published in Pain (Amsterdam) (01.11.2010)
Published in Pain (Amsterdam) (01.11.2010)
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Journal Article
On the link between Bcl-2 family proteins and glucocorticoid-induced apoptosis
Almawi, Wassim Y., Melemedjian, Ohannes K., Jaoude, Maroun M. Abou
Published in Journal of leukocyte biology (01.07.2004)
Published in Journal of leukocyte biology (01.07.2004)
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Journal Article
A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors
François-Moutal, Liberty, Wang, Yue, Moutal, Aubin, Cottier, Karissa E., Melemedjian, Ohannes K., Yang, Xiaofang, Wang, Yuying, Ju, Weina, Largent-Milnes, Tally M., Khanna, May, Vanderah, Todd W., Khanna, Rajesh
Published in Pain (Amsterdam) (01.07.2015)
Published in Pain (Amsterdam) (01.07.2015)
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Journal Article
Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization
Asiedu, Marina N, Tillu, Dipti V, Melemedjian, Ohannes K, Shy, Adia, Sanoja, Raul, Bodell, Bryce, Ghosh, Sourav, Porreca, Frank, Price, Theodore J
Published in The Journal of neuroscience (04.05.2011)
Published in The Journal of neuroscience (04.05.2011)
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Journal Article