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Hecker, Louise, Logsdon, Naomi J, Kurundkar, Deepali, Kurundkar, Ashish, Bernard, Karen, Hock, Thomas, Meldrum, Eric, Sanders, Yan Y, Thannickal, Victor J
Published in Science translational medicine (09.04.2014)
Published in Science translational medicine (09.04.2014)
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Niclosamide is a proton carrier and targets acidic endosomes with broad antiviral effects
Jurgeit, Andreas, McDowell, Robert, Moese, Stefan, Meldrum, Eric, Schwendener, Reto, Greber, Urs F
Published in PLoS pathogens (01.10.2012)
Published in PLoS pathogens (01.10.2012)
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Mitochondrial morphodynamics alteration induced by influenza virus infection as a new antiviral strategy
Pila-Castellanos, Irene, Molino, Diana, McKellar, Joe, Lines, Laetitia, Da Graca, Juliane, Tauziet, Marine, Chanteloup, Laurent, Mikaelian, Ivan, Meyniel-Schicklin, Laurène, Codogno, Patrice, Vonderscher, Jacky, Delevoye, Cédric, Moncorgé, Olivier, Meldrum, Eric, Goujon, Caroline, Morel, Etienne, de Chassey, Benoit
Published in PLoS pathogens (01.02.2021)
Published in PLoS pathogens (01.02.2021)
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Viruses traverse the human proteome through peptide interfaces that can be biomimetically leveraged for drug discovery
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Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2024)
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Correction: Mitochondrial morphodynamics alteration induced by influenza virus infection as a new antiviral strategy
Pila-Castellanos, Irene, Molino, Diana, McKellar, Joe, Lines, Laetitia, Da Graca, Juliane, Tauziet, Marine, Chanteloup, Laurent, Mikaelian, Ivan, Meyniel-Schicklin, Laurène, Codogno, Patrice, Vonderscher, Jacky, Delevoye, Cédric, Moncorgé, Olivier, Meldrum, Eric, Goujon, Caroline, Morel, Etienne, de Chassey, Benoit
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Published in PLoS pathogens (31.03.2021)
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Anti-citrullinated histone monoclonal antibody CIT-013, a dual action therapeutic for neutrophil extracellular trap-associated autoimmune diseases
van der Linden, Maarten, Kumari, Sangeeta, Montizaan, Daphne, van Dalen, Stephanie, Kip, Annemarie, Foster, Martyn, Reinieren-Beeren, Inge, Neubert, Elsa, Erpenbeck, Luise, Waaijenberg, Kelsy, Bruurmijn, Tirza, Te Poele, Rezie, van Zandvoort, Peter, Vink, Paul, Meldrum, Eric, van Es, Helmuth, Chirivi, Renato G S
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Published in mAbs (2023)
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An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters
Marjault, Henri-Baptiste, Karmi, Ola, Zuo, Ke, Michaeli, Dorit, Eisenberg-Domovich, Yael, Rossetti, Giulia, de Chassey, Benoit, Vonderscher, Jacky, Cabantchik, Ioav, Carloni, Paolo, Mittler, Ron, Livnah, Oded, Meldrum, Eric, Nechushtai, Rachel
Published in Communications biology (10.05.2022)
Published in Communications biology (10.05.2022)
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A genome-based approach for the identification of essential bacterial genes
Arigoni, Fabrizio, Talabot, Francois, Peitsch, Manuel, Edgerton, Michael D, Meldrum, Eric, Allet, Elisabeth, Fish, Richard, Jamotte, Therese, Curchod, Marie-Laure, Loferer, Hannes
Published in Nature biotechnology (01.09.1998)
Published in Nature biotechnology (01.09.1998)
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The PtdIns-PLC superfamily and signal transduction
Meldrum, Eric, Parker, Peter J., Carozzi, Amanda
Published in BBA - Molecular Cell Research (19.03.1991)
Published in BBA - Molecular Cell Research (19.03.1991)
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FRI110 - Characterization of EYP001 a novel, potent and selective FXR agonist in in vitro 3D human liver models of NASH
Radreau - Pierini, Pauline, Joly, Stéphane, Vonderscher, Jacky, Scalfaro, Pietro, Eric, Meldrum, Darteil, Raphaël
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
Characterization of EYP001 a novel, potent and selective FXR agonist in in vitro 3D human liver models of NASH
Radreau - Pierini, Pauline, Joly, Stéphane, Vonderscher, Jacky, Scalfaro, Pietro, Eric, Meldrum, Darteil, Raphaël
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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A Novel Small Molecule Modulating the Mitochondrial NEET Proteins Improves Inflammation and Fibrosis in Kidneys of Nonalcoholic Steatohepatitis Mice: PO0651
Terzi, Fabiola, Le Corre, Stéphanie, Vasseur, Florence, Sampson, Diane, Radreau, Pauline, De Chassey, Benoit, Vonderscher, Jacky, Darteil, Raphael, Meldrum, Eric
Published in Journal of the American Society of Nephrology (01.10.2020)
Published in Journal of the American Society of Nephrology (01.10.2020)
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A novel small molecule modulating the mitochondrial NEET (CISD) proteins activity improves inflammation and fibrosis in a diet-induced model of non-alcoholic steatohepatitis
Le Corre, Stéphanie, Laetitia, Lines, Diane, Sampson, Ola, Karmi, Henri-Baptiste, Margault, Rodrigue, Rossignol, Nivea, Amoedo, Rachel, Nechushtai, Darteil, Raphaël, Vonderscher, Jacky, Benoit, De Chassey, Eric, Meldrum
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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SAT061 - A novel small molecule modulating the mitochondrial NEET (CISD) proteins activity improves inflammation and fibrosis in a diet-induced model of non-alcoholic steatohepatitis
Le Corre, Stéphanie, Laetitia, Lines, Diane, Sampson, Ola, Karmi, Henri-Baptiste, Margault, Rodrigue, Rossignol, Nivea, Amoedo, Rachel, Nechushtai, Darteil, Raphaël, Vonderscher, Jacky, Benoit, De Chassey, Eric, Meldrum
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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세포 외 트랩 억제
CHIRIVI RENATO GERARDUS SILVANO, MONTIZAAN DAPHNE, MELDRUM ERIC CHARLES, VAN ES HELMUTH HENDRIKUS GERARDUS
Year of Publication 12.01.2024
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Year of Publication 12.01.2024
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Chemical targeting of NEET proteins reveals their function in mitochondrial morphodynamics
Molino, Diana, Pila‐Castellanos, Irene, Marjault, Henri‐Baptiste, Dias Amoedo, Nivea, Kopp, Katja, Rochin, Leila, Karmi, Ola, Sohn, Yang‐Sung, Lines, Laetitia, Hamaï, Ahmed, Joly, Stéphane, Radreau, Pauline, Vonderscher, Jacky, Codogno, Patrice, Giordano, Francesca, Machin, Peter, Rossignol, Rodrigue, Meldrum, Eric, Arnoult, Damien, Ruggieri, Alessia, Nechushtai, Rachel, de Chassey, Benoit, Morel, Etienne
Published in EMBO reports (03.12.2020)
Published in EMBO reports (03.12.2020)
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A novel lung explant model for the ex vivo study of efficacy and mechanisms of anti-influenza drugs
Nicholas, Ben, Staples, Karl J, Moese, Stefan, Meldrum, Eric, Ward, Jon, Dennison, Patrick, Havelock, Tom, Hinks, Timothy S C, Amer, Khalid, Woo, Edwin, Chamberlain, Martin, Singh, Neeta, North, Malcolm, Pink, Sandy, Wilkinson, Tom M A, Djukanović, Ratko
Published in The Journal of immunology (1950) (15.06.2015)
Published in The Journal of immunology (1950) (15.06.2015)
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만성 신장 질환의 치료 방법
DARTEIL RAPHAEL, MELDRUM ERIC, TERZI FABIOLA, VONDERSCHER JACKY, LE CORRE STEPHANIE
Year of Publication 11.04.2023
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Year of Publication 11.04.2023
Patent
NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES
MACHIN PETER, MELDRUM ERIC, MALAGU KARINE FABIENNE, KNIGHT JAMIE DAVID, WINSHIP PAUL COLIN MICHAEL, LANARO ROBERTA, PAPARIN JEAN LAURENT, CHAMBERS MARK, DE CHASSEY BENOIT
Year of Publication 30.08.2024
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Year of Publication 30.08.2024
Patent