Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of β-thalassemia intermedia and major
Casu, Carla, Presti, Vania Lo, Oikonomidou, Paraskevi Rea, Melchiori, Luca, Abdulmalik, Osheiza, Ramos, Pedro, Rivella, Stefano
Published in Haematologica (Roma) (01.02.2018)
Published in Haematologica (Roma) (01.02.2018)
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Long‐term safety and activity of NY-ESO‐1 SPEAR T cells after autologous stem cell transplant for myeloma
Stadtmauer, Edward A., Faitg, Thomas H., Lowther, Daniel E., Badros, Ashraf Z., Chagin, Karen, Dengel, Karen, Iyengar, Malini, Melchiori, Luca, Navenot, Jean-Marc, Norry, Elliot, Trivedi, Trupti, Wang, Ruoxi, Binder, Gwendolyn K., Amado, Rafael, Rapoport, Aaron P.
Published in Blood advances (09.07.2019)
Published in Blood advances (09.07.2019)
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Hyperforin down-regulates effector function of activated T lymphocytes and shows efficacy against Th1-triggered CNS inflammatory-demyelinating disease
Cabrelle, Anna, Dell’Aica, Isabella, Melchiori, Luca, Carraro, Samuela, Brunetta, Enrico, Niero, Raffaele, Scquizzato, Elisa, D’Intino, Giulia, Calzà, Laura, Garbisa, Spiridione, Agostini, Carlo
Published in Journal of leukocyte biology (01.01.2008)
Published in Journal of leukocyte biology (01.01.2008)
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Journal Article
NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma
Rapoport, Aaron P, Stadtmauer, Edward A, Binder-Scholl, Gwendolyn K, Goloubeva, Olga, Vogl, Dan T, Lacey, Simon F, Badros, Ashraf Z, Garfall, Alfred, Weiss, Brendan, Finklestein, Jeffrey, Kulikovskaya, Irina, Sinha, Sanjoy K, Kronsberg, Shari, Gupta, Minnal, Bond, Sarah, Melchiori, Luca, Brewer, Joanna E, Bennett, Alan D, Gerry, Andrew B, Pumphrey, Nicholas J, Williams, Daniel, Tayton- Martin, Helen K, Ribeiro, Lilliam, Holdich, Tom, Yanovich, Saul, Hardy, Nancy, Yared, Jean, Kerr, Naseem, Philip, Sunita, Westphal, Sandra, Siegel, Don L, Levine, Bruce L, Jakobsen, Bent K, Kalos, Michael, June, Carl H
Published in Nature medicine (01.08.2015)
Published in Nature medicine (01.08.2015)
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Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice
Gardenghi, Sara, Ramos, Pedro, Marongiu, Maria Franca, Melchiori, Luca, Breda, Laura, Guy, Ella, Muirhead, Kristen, Rao, Niva, Roy, Cindy N, Andrews, Nancy C, Nemeth, Elizabeta, Follenzi, Antonia, An, Xiuli, Mohandas, Narla, Ginzburg, Yelena, Rachmilewitz, Eliezer A, Giardina, Patricia J, Grady, Robert W, Rivella, Stefano
Published in The Journal of clinical investigation (01.12.2010)
Published in The Journal of clinical investigation (01.12.2010)
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Journal Article
Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma
Ramachandran, Indu, Lowther, Daniel E., Dryer-Minnerly, Rebecca, Wang, Ruoxi, Fayngerts, Svetlana, Nunez, Daniel, Betts, Gareth, Bath, Natalie, Tipping, Alex J., Melchiori, Luca, Navenot, Jean-Marc, Glod, John, Mackall, Crystal L., D’Angelo, Sandra P., Araujo, Dejka M., Chow, Warren A., Demetri, George D., Druta, Mihaela, Van Tine, Brian A., Grupp, Stephan A., Abdul Razak, Albiruni R., Wilky, Breelyn, Iyengar, Malini, Trivedi, Trupti, Winkle, Erin Van, Chagin, Karen, Amado, Rafael, Binder, Gwendolyn K., Basu, Samik
Published in Journal for immunotherapy of cancer (24.10.2019)
Published in Journal for immunotherapy of cancer (24.10.2019)
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Journal Article
Potential Therapeutic Applications of Jak2 Inhibitors and Hif2a-ASO for the Treatment of β-Thalassemia Intermedia and Major
Casu, Carla, Oikonomidou, Paraskevi Rea, Lo Presti, Vania, Aghajan, Mariam, Guo, Shuling, Osheiza, Abdulmalik, Melchiori, Luca, Ramos, Pedro, Rivella, Stefano
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Enhancing Efficacy of TCR-engineered CD4 + T Cells Via Coexpression of CD8α
Anderson, Victoria E, Brilha, Sara S, Weber, Anika M, Pachnio, Annette, Wiedermann, Guy E, Dauleh, Sumaya, Ahmed, Tina, Pope, George R, Quinn, Laura L, Docta, Roslin Y, Quattrini, Adriano, Masters, Siobhan, Cartwright, Neil, Viswanathan, Preetha, Melchiori, Luca, Rice, Louise V, Sevko, Alexandra, Gueguen, Claire, Saini, Manoj, Tavano, Barbara, Abbott, Rachel J M, Silk, Jonathan D, Laugel, Bruno, Sanderson, Joseph P, Gerry, Andrew B
Published in Journal of immunotherapy (1997) (01.05.2023)
Published in Journal of immunotherapy (1997) (01.05.2023)
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Journal Article
Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in β-thalassemia
Libani, Ilaria V., Guy, Ella C., Melchiori, Luca, Schiro, Raffaella, Ramos, Pedro, Breda, Laura, Scholzen, Thomas, Chadburn, Amy, Liu, YiFang, Kernbach, Margrit, Baron-Lühr, Bettina, Porotto, Matteo, de Sousa, Maria, Rachmilewitz, Eliezer A., Hood, John D., Cappellini, M. Domenica, Giardina, Patricia J., Grady, Robert W., Gerdes, Johannes, Rivella, Stefano
Published in Blood (01.08.2008)
Published in Blood (01.08.2008)
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Journal Article
192. Deep Phenotyping of Manufactured Enhanced-Affinity NY-ESO-1-Specific T Cells Reveals a Pattern of Effector and Memory Programming That Correlates with Clinical Outcome in Observed Cancer Indications
Melchiori, Luca, Lowther, Daniel E., Binder-Scholl, Gwendolyn K., Williams, Daniel D., Peretz, Yoav, Fortin, Marylene, Tap, Willian D., Rapoport, Aaron P., Mackall, Crystal L., Jakobsen, Bent K.
Published in Molecular therapy (01.05.2016)
Published in Molecular therapy (01.05.2016)
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Journal Article
Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1c259T Cells in Synovial Sarcoma
D'Angelo, Sandra P., Melchiori, Luca, Merchant, Melinda S., Bernstein, Donna, Glod, John, Kaplan, Rosandra, Grupp, Stephan, Tap, William D., Chagin, Karen, Binder, Gwendolyn K., Basu, Samik, Lowther, Daniel E., Wang, Ruoxi, Bath, Natalie, Tipping, Alex, Betts, Gareth, Ramachandran, Indu, Navenot, Jean-Marc, Zhang, Hua, Wells, Daniel K., Winkle, Erin Van, Kari, Gabor, Trivedi, Trupti, Holdich, Tom, Pandite, Lini, Amado, Rafael, Mackall, Crystal L.
Published in Cancer discovery (11.06.2018)
Published in Cancer discovery (11.06.2018)
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Journal Article
Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma
D'Angelo, Sandra P., Melchiori, Luca, Merchant, Melinda S., Bernstein, Donna, Glod, John, Kaplan, Rosandra, Grupp, Stephan, Tap, William D., Chagin, Karen, Binder, Gwendolyn K., Basu, Samik, Lowther, Daniel E., Wang, Ruoxi, Bath, Natalie, Tipping, Alex, Betts, Gareth, Ramachandran, Indu, Navenot, Jean-Marc, Zhang, Hua, Wells, Daniel K., Van Winkle, Erin, Kari, Gabor, Trivedi, Trupti, Holdich, Tom, Pandite, Lini, Amado, Rafael, Mackall, Crystal L.
Published in Cancer discovery (01.08.2018)
Published in Cancer discovery (01.08.2018)
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Journal Article
Abstract 4707: Genetically engineered NY-ESO-1-specific T cells in HLA-A2+ patients with synovial sarcoma
Merchant, Melinda S., D'Angelo, Sandra P., Zhang, Hua, Bernstein, Donna, Binder-Scholl, Gwen, Holdich, Tom, Melchiori, Luca, Williams, Dan, Fortin, Marylene, Peretz, Yoav, Howe, Jason, Mehler, Michael, Hug, Bruce A., Wright, Matthew, Grupp, Stephen, Meyers, Paul A., Tap, William, Jakobsen, Bent, Mackall, Crystal L.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 4701: NY-ESO T cells administered post ASCT for MM exhibit extended functionality without exhaustion in a natural pattern of effector and memory programming
Rapoport, Aaron, Stadtmauer, Edward, Melchiori, Luca, Wong, Ryan, Davila, Eduardo, Binder-Scholl, Gwendolyn, Holdich, Tom, Vogl, Dan, Weiss, Brendan, Finkelstein, Jeffrey, Lacey, Simon, Bond, Sarah, Fortin, Marylene, Peretz, Yoav, Brewer, Joanna, Bennett, Alan, Gerry, Andrew, Pumphrey, Nick, Tayton-Martin, Helen, Ribeiro, Lilliam, Badros, Ashraf, Yanovich, Saul, Hardy, Nancy, Yared, Jean, Kerr, Naseem, Philip, Sunita, Wesphal, Sandra, Levine, Bruce L., June, Carl, Kalos, Michael, Jakobsen, Bent
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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511. Enhanced-Affinity NY-ESO-1-Specific T Cells Exhibit Extended Functionality without Exhaustion in a Pattern of Effector and Memory Programming in Multiple Cancer Indications
Melchiori, Luca, Williams, Daniel D., Binder-Scholl, Gwendolyn K., Wong, Ryan, Kreutz, Martin, Tayton-Martin, Helen K., Stadtmauer, Edward, Vogl, Dan T., Merchant, Melinda, Tap, William, D'Angelo, Sandra, Davila, Eduardo, Fortin, Marylene, Peretz, Yoav, Rapoport, Aaron P., Mackall, Crystal, Jakobsen, Bent K.
Published in Molecular therapy (01.05.2015)
Published in Molecular therapy (01.05.2015)
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