Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism
Snelders, Eveline, van der Lee, Henrich A L, Kuijpers, Judith, Rijs, Anthonius J M M, Varga, János, Samson, Robert A, Mellado, Emilia, Donders, A Rogier T, Melchers, Willem J G, Verweij, Paul E
Published in PLoS medicine (01.11.2008)
Published in PLoS medicine (01.11.2008)
Get full text
Journal Article
Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis
Quainoo, Scott, Coolen, Jordy P M, van Hijum, Sacha A F T, Huynen, Martijn A, Melchers, Willem J G, van Schaik, Willem, Wertheim, Heiman F L
Published in Clinical microbiology reviews (01.10.2017)
Published in Clinical microbiology reviews (01.10.2017)
Get full text
Journal Article
Aspergillosis due to Voriconazole Highly Resistant Aspergillus fumigatus and Recovery of Genetically Related Resistant Isolates From Domiciles
van der Linden, Jan W. M., Camps, Simone M. T., Kampinga, Greetje A., Arends, Jan P. A., Debets-Ossenkopp, Yvette J., Haas, Pieter J. A., Rijnders, Bart J. A., Kujiper, Ed J., van Tiel, Frank H., Varga, János, Karawajczyk, Anna, Zoll, J., Melchers, Willem J. G., Verweij, Paul E.
Published in Clinical infectious diseases (15.08.2013)
Published in Clinical infectious diseases (15.08.2013)
Get full text
Journal Article
Voriconazole Resistance and Mortality in Invasive Aspergillosis: A Multicenter Retrospective Cohort Study
Lestrade, Pieter P, Bentvelsen, Robbert G, Schauwvlieghe, Alexander F A D, Schalekamp, Steven, van der Velden, Walter J F M, Kuiper, Ed J, van Paassen, Judith, van der Hoven, Ben, van der Lee, Henrich A, Melchers, Willem J G, de Haan, Anton F, van der Hoeven, Hans L, Rijnders, Bart J A, van der Beek, Martha T, Verweij, Paul E
Published in Clinical infectious diseases (24.04.2019)
Published in Clinical infectious diseases (24.04.2019)
Get full text
Journal Article
Azole Resistance Profile of Amino Acid Changes in Aspergillus fumigatus CYP51A Based on Protein Homology Modeling
SNELDERS, Eveline, KARAWAJCZYK, Anna, SCHAFTENAAR, Gijs, VERWEIJ, Paul E, MELCHERS, Willem J. G
Published in Antimicrobial Agents and Chemotherapy (01.06.2010)
Published in Antimicrobial Agents and Chemotherapy (01.06.2010)
Get full text
Journal Article
Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus
Snelders, Eveline, Camps, Simone M T, Karawajczyk, Anna, Schaftenaar, Gijs, Kema, Gert H J, van der Lee, Henrich A, Klaassen, Corné H, Melchers, Willem J G, Verweij, Paul E
Published in PloS one (01.03.2012)
Published in PloS one (01.03.2012)
Get full text
Journal Article
Discovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing
Camps, Simone M T, Dutilh, Bas E, Arendrup, Maiken C, Rijs, Antonius J M M, Snelders, Eveline, Huynen, Martijn A, Verweij, Paul E, Melchers, Willem J G
Published in PloS one (30.11.2012)
Published in PloS one (30.11.2012)
Get full text
Journal Article
Rapid Induction of Multiple Resistance Mechanisms in Aspergillus fumigatus during Azole Therapy: a Case Study and Review of the Literature
CAMPS, Simone M. T, VAN DER LINDEN, Jan W. M, YI LI, KUIJPER, Ed J, VAN DISSEL, Jaap T, VERWEIJ, Paul E, MELCHERS, Willem J. G
Published in Antimicrobial Agents and Chemotherapy (01.01.2012)
Published in Antimicrobial Agents and Chemotherapy (01.01.2012)
Get full text
Journal Article
Possible Environmental Origin of Resistance of Aspergillus fumigatus to Medical Triazoles
Snelders, Eveline, Huis in 't Veld, Robert A.G, Rijs, Anthonius J.M.M, Kema, Gert H.J, Melchers, Willem J.G, Verweij, Paul E
Published in Applied and Environmental Microbiology (01.06.2009)
Published in Applied and Environmental Microbiology (01.06.2009)
Get full text
Journal Article
Temporal composition of the cervicovaginal microbiome associates with hrHPV infection outcomes in a longitudinal study
Molina, Mariano A, Leenders, William P J, Huynen, Martijn A, Melchers, Willem J G, Andralojc, Karolina M
Published in BMC infectious diseases (03.06.2024)
Published in BMC infectious diseases (03.06.2024)
Get full text
Journal Article
Pharmacodynamics of isavuconazole in an Aspergillus fumigatus mouse infection model
Seyedmousavi, Seyedmojtaba, Brüggemann, Roger J M, Meis, Jacques F, Melchers, Willem J G, Verweij, Paul E, Mouton, Johan W
Published in Antimicrobial agents and chemotherapy (01.05.2015)
Published in Antimicrobial agents and chemotherapy (01.05.2015)
Get full text
Journal Article
A New Aspergillus fumigatus Resistance Mechanism Conferring In Vitro Cross-Resistance to Azole Antifungals Involves a Combination of cyp51A Alterations
MELLADO, E, GARCIA-EFFRON, G, ALCAZAR-FUOLI, L, MELCHERS, W. J. G, VERWEIJ, P. E, CUENCA-ESTRELLA, M, RODRIGUEZ-TUDELA, J. L
Published in Antimicrobial Agents and Chemotherapy (01.06.2007)
Published in Antimicrobial Agents and Chemotherapy (01.06.2007)
Get full text
Journal Article
Azole, polyene and echinocandin MIC distributions for wild-type, TR34/L98H and TR46/Y121F/T289A Aspergillus fumigatus isolates in the Netherlands
van Ingen, Jakko, van der Lee, Henrich A, Rijs, Ton A J, Zoll, Jan, Leenstra, Tjalling, Melchers, Willem J G, Verweij, Paul E
Published in Journal of antimicrobial chemotherapy (01.01.2015)
Published in Journal of antimicrobial chemotherapy (01.01.2015)
Get full text
Journal Article
Impact of the BioFire FilmArray gastrointestinal panel on patient care and infection control
Machiels, Julian D, Cremers, Amelieke J H, van Bergen-Verkuyten, Muriël C G T, Paardekoper-Strijbosch, Sandra J M, Frijns, Kelly C J, Wertheim, Heiman F L, Rahamat-Langendoen, Janette, Melchers, Willem J G
Published in PloS one (06.02.2020)
Published in PloS one (06.02.2020)
Get full text
Journal Article
Aspergillus PCR: One Step Closer to Standardization
White, P. Lewis, Bretagne, Stéphane, Klingspor, Lena, Melchers, Willem J.G, McCulloch, Elaine, Schulz, Bettina, Finnstrom, Niklas, Mengoli, Carlo, Barnes, Rosemary A, Donnelly, J. Peter, Loeffler, Juergen
Published in Journal of Clinical Microbiology (01.04.2010)
Published in Journal of Clinical Microbiology (01.04.2010)
Get full text
Journal Article