Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma
Close, H. J., Stead, L. F., Nsengimana, J., Reilly, K. A., Droop, A., Wurdak, H., Mathew, R. K., Corns, R., Newton‐Bishop, J., Melcher, A. A., Short, S. C., Cook, G. P., Wilson, E. B.
Published in Clinical and experimental immunology (01.04.2020)
Published in Clinical and experimental immunology (01.04.2020)
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Recent clinical experience with oncolytic viruses
Donnelly, O G, Errington-Mais, F, Prestwich, R, Harrington, K, Pandha, H, Vile, R, Melcher, A A
Published in Current pharmaceutical biotechnology (01.07.2012)
Published in Current pharmaceutical biotechnology (01.07.2012)
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Response of Fish Communities to Hydrological and Morphological Alterations in Hydropeaking Rivers of Austria
Schmutz, S., Bakken, T. H., Friedrich, T., Greimel, F., Harby, A., Jungwirth, M., Melcher, A., Unfer, G., Zeiringer, B.
Published in River research and applications (01.10.2015)
Published in River research and applications (01.10.2015)
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Journal Article
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade
Samson, Adel, Scott, Karen J, Taggart, David, West, Emma J, Wilson, Erica, Nuovo, Gerard J, Thomson, Simon, Corns, Robert, Mathew, Ryan K, Fuller, Martin J, Kottke, Timothy J, Thompson, Jill M, Ilett, Elizabeth J, Cockle, Julia V, van Hille, Philip, Sivakumar, Gnanamurthy, Polson, Euan S, Turnbull, Samantha J, Appleton, Elizabeth S, Migneco, Gemma, Rose, Ailsa S, Coffey, Matthew C, Beirne, Deborah A, Collinson, Fiona J, Ralph, Christy, Alan Anthoney, D, Twelves, Christopher J, Furness, Andrew J, Quezada, Sergio A, Wurdak, Heiko, Errington-Mais, Fiona, Pandha, Hardev, Harrington, Kevin J, Selby, Peter J, Vile, Richard G, Griffin, Stephen D, Stead, Lucy F, Short, Susan C, Melcher, Alan A
Published in Science translational medicine (03.01.2018)
Published in Science translational medicine (03.01.2018)
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Journal Article
The immunological consequences of radiation‐induced DNA damage
Wilkins, Anna C, Patin, Emmanuel C, Harrington, Kevin J, Melcher, Alan A
Published in The Journal of pathology (01.04.2019)
Published in The Journal of pathology (01.04.2019)
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Using macroinvertebrates for ecosystem health assessment in semi-arid streams of Burkina Faso
Kaboré, Idrissa, Moog, O, Alp, M, Guenda, W, Koblinger, T, Mano, K, Ouéda, A, Ouédraogo, R, Trauner, D, Melcher, A. H
Published in Hydrobiologia (01.02.2016)
Published in Hydrobiologia (01.02.2016)
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OX40 and 4-1BB delineate distinct immune profiles in sarcoma
Melake, MJ, Smith, HG, Mansfield, D, Davies, E, Dillon, MT, Wilkins, AC, Patin, EC, Pedersen, M, Buus, R, Melcher, AA, Thway, K, Miah, AB, Zaidi, SH, Hayes, AJ, Fenton, TR, Harrington, KJ, McLaughlin, M
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial
White, C L, Twigger, K R, Vidal, L, De Bono, J S, Coffey, M, Heinemann, L, Morgan, R, Merrick, A, Errington, F, Vile, R G, Melcher, A A, Pandha, H S, Harrington, K J
Published in Gene therapy (01.06.2008)
Published in Gene therapy (01.06.2008)
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A benthic invertebrates-based biotic index to assess the ecological status of West African Sahel Rivers, Burkina Faso
Kaboré, Idrissa, Ouéda, A., Moog, O., Meulenbroek, P., Tampo, L., Bancé, V., Melcher, A.H.
Published in Journal of environmental management (01.04.2022)
Published in Journal of environmental management (01.04.2022)
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Journal Article
Measles virus causes immunogenic cell death in human melanoma
Donnelly, O G, Errington-Mais, F, Steele, L, Hadac, E, Jennings, V, Scott, K, Peach, H, Phillips, R M, Bond, J, Pandha, H, Harrington, K, Vile, R, Russell, S, Selby, P, Melcher, A A
Published in Gene therapy (01.01.2013)
Published in Gene therapy (01.01.2013)
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Journal Article
Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma
McKelvey, Kelly J, Wilson, Erica B, Short, Susan, Melcher, Alan A, Biggs, Michael, Diakos, Connie I, Howell, Viive M
Published in Frontiers in oncology (29.03.2021)
Published in Frontiers in oncology (29.03.2021)
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Journal Article
RE-ARMing the Immune Response to Bladder Cancer with Radiotherapy
Wilkins, A., Hall, E., Lewis, R., Gribble, H., Melcher, A., Huddart, R.
Published in Clinical oncology (Royal College of Radiologists (Great Britain)) (01.07.2022)
Published in Clinical oncology (Royal College of Radiologists (Great Britain)) (01.07.2022)
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Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy
Chan Wah Hak, Charleen M L, Rullan, Antonio, Patin, Emmanuel C, Pedersen, Malin, Melcher, Alan A, Harrington, Kevin J
Published in Frontiers in oncology (29.08.2022)
Published in Frontiers in oncology (29.08.2022)
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Journal Article
Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity
Wilson, Erica B, El-Jawhari, Jehan J, Neilson, Abbie L, Hall, Geoffrey D, Melcher, Alan A, Meade, Josephine L, Cook, Graham P
Published in PloS one (06.09.2011)
Published in PloS one (06.09.2011)
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Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy
Patin, Emmanuel C., Nenclares, Pablo, Chan Wah Hak, Charleen, Dillon, Magnus T., Patrikeev, Anton, McLaughlin, Martin, Grove, Lorna, Foo, Shane, Soliman, Heba, Barata, Joao P., Marsden, Joanna, Baldock, Holly, Gkantalis, Jim, Roulstone, Victoria, Kyula, Joan, Burley, Amy, Hubbard, Lisa, Pedersen, Malin, Smith, Simon A., Clancy-Thompson, Eleanor, Melcher, Alan A., Ono, Masahiro, Rullan, Antonio, Harrington, Kevin J.
Published in Nature communications (13.08.2024)
Published in Nature communications (13.08.2024)
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Journal Article
The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study
Punta, Marco, Jennings, Victoria A, Melcher, Alan A, Lise, Stefano
Published in Frontiers in immunology (08.10.2020)
Published in Frontiers in immunology (08.10.2020)
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Journal Article
Assessing River Biotic Condition at a Continental Scale: A European Approach Using Functional Metrics and Fish Assemblages
Pont, D., Hugueny, B., Beier, U., Goffaux, D., Melcher, A., Noble, R., Rogers, C., Roset, N., Schmutz, S.
Published in The Journal of applied ecology (01.02.2006)
Published in The Journal of applied ecology (01.02.2006)
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Journal Article
Lymphokine‐activated killer and dendritic cell carriage enhances oncolytic reovirus therapy for ovarian cancer by overcoming antibody neutralization in ascites
Jennings, V.A., Ilett, E.J., Scott, K.J., West, E.J., Vile, R., Pandha, H., Harrington, K., Young, A., Hall, G.D., Coffey, M., Selby, P., Errington‐Mais, F., Melcher, A.A.
Published in International journal of cancer (01.03.2014)
Published in International journal of cancer (01.03.2014)
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Journal Article
Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade
Patin, Emmanuel C, Dillon, Magnus T, Nenclares, Pablo, Grove, Lorna, Soliman, Heba, Leslie, Isla, Northcote, Davina, Bozhanova, Galabina, Crespo-Rodriguez, Eva, Baldock, Holly, Whittock, Harriet, Baker, Gabriella, Kyula, Joan, Guevara, Jeane, Melcher, Alan A, Harper, James, Ghadially, Hormas, Smith, Simon, Pedersen, Malin, McLaughlin, Martin, Harrington, Kevin J
Published in Journal for immunotherapy of cancer (01.03.2022)
Published in Journal for immunotherapy of cancer (01.03.2022)
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