Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator
Liu, Chang, Zhang, Hua, Peng, Xian, Blackledge, Meghan S, Furlani, Robert E, Li, Haoting, Su, Zhaoming, Melander, Roberta J, Melander, Christian, Michalek, Suzanne, Wu, Hui
Published in mBio (27.06.2023)
Published in mBio (27.06.2023)
Get full text
Journal Article
Advanced Glycation End Products as a Potential Target for Restructuring the Ovarian Cancer Microenvironment: A Pilot Study
Harper, Elizabeth I, Siroky, Michael D, Hilliard, Tyvette S, Dominique, Gena M, Hammond, Catherine, Liu, Yueying, Yang, Jing, Hubble, Veronica B, Walsh, Danica J, Melander, Roberta J, Melander, Christian, Ravosa, Matthew J, Stack, M Sharon
Published in International journal of molecular sciences (01.06.2023)
Published in International journal of molecular sciences (01.06.2023)
Get full text
Journal Article
Natural products as inspiration for the development of bacterial antibiofilm agents
Melander, Roberta J, Basak, Akash K, Melander, Christian
Published in Natural product reports (01.11.2020)
Published in Natural product reports (01.11.2020)
Get full text
Journal Article
Controlling bacterial behavior with indole-containing natural products and derivatives
Melander, Roberta J., Minvielle, Marine J., Melander, Christian
Published in Tetrahedron (16.09.2014)
Published in Tetrahedron (16.09.2014)
Get full text
Journal Article
Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp
Milton, Morgan E, Minrovic, Bradley M, Harris, Danni L, Kang, Brian, Jung, David, Lewis, Caleb P, Thompson, Richele J, Melander, Roberta J, Zeng, Daina, Melander, Christian, Cavanagh, John
Published in Frontiers in molecular biosciences (13.02.2018)
Published in Frontiers in molecular biosciences (13.02.2018)
Get full text
Journal Article
Adjuvants restore colistin sensitivity in mouse models of highly colistin-resistant isolates, limiting bacterial proliferation and dissemination
Koller, Beverly H., Jania, Leigh A., Li, Haoting, Barker, William T., Melander, Roberta J., Melander, Christian
Published in Antimicrobial agents and chemotherapy (28.08.2024)
Published in Antimicrobial agents and chemotherapy (28.08.2024)
Get full text
Journal Article
Synthesis, Stereochemical Confirmation, and Derivatization of 12(S),16ϵ‐Dihydroxycleroda‐3,13‐dien‐15,16‐olide, a Clerodane Diterpene That Sensitizes Methicillin‐Resistant Staphylococcus aureus to β‐Lactam Antibiotics
Zeiler, Michael J., Connors, Gina M., Durling, Greg M., Oliver, Allen G., Marquez, Lewis, Melander, Roberta J., Quave, Cassandra L., Melander, Christian
Published in Angewandte Chemie International Edition (19.04.2022)
Published in Angewandte Chemie International Edition (19.04.2022)
Get full text
Journal Article
Development of small molecules that work cooperatively with ciprofloxacin to clear salmonella biofilms in a chronic gallbladder carriage model
Woolard, Katherine J., Sandala, Jenna L., Melander, Roberta J., Gunn, John S., Melander, Christian
Published in European journal of medicinal chemistry (15.03.2022)
Published in European journal of medicinal chemistry (15.03.2022)
Get full text
Journal Article
Identification of a 2‐Aminobenzimidazole Scaffold that Potentiates Gram‐Positive Selective Antibiotics Against Gram‐Negative Bacteria
Nemeth, Ansley M., Young, Milah M., Melander, Roberta J., Smith, Richard D., Ernst, Robert K., Melander, Christian
Published in Chembiochem : a European journal of chemical biology (16.04.2024)
Published in Chembiochem : a European journal of chemical biology (16.04.2024)
Get full text
Journal Article
Synthesis, Stereochemical Resolution, and Analogue Synthesis of Variabiline, an Aporphine Alkaloid That Sensitizes Acinetobacter baumannii and Klebsiella pneumoniae to Colistin
Li, Haoting, Nemeth, Ansley M., Melander, Roberta J., Melander, Christian
Published in ACS infectious diseases (12.04.2024)
Published in ACS infectious diseases (12.04.2024)
Get full text
Journal Article
Synthesis and biofilm inhibition studies of 2-(2-amino-6-arylpyrimidin-4-yl)quinazolin-4(3H)-ones
Rasapalli, Sivappa, Murphy, Zachary F., Sammeta, Vamshikrishna Reddy, Golen, James A., Weig, Alexander W., Melander, Roberta J., Melander, Christian, Macha, Prathyushakrishna, Vasudev, Milana C.
Published in Bioorganic & medicinal chemistry letters (01.12.2020)
Published in Bioorganic & medicinal chemistry letters (01.12.2020)
Get full text
Journal Article
Dimeric 2-aminoimidazoles are highly active adjuvants for gram-positive selective antibiotics against Acinetobacter baumannii
Marrujo, Santiana A., Hubble, Veronica B., Yang, Jingdong, Wang, Man, Nemeth, Ansley M., Barlock, Samantha L., Juarez, Dane, Smith, Richard D., Melander, Roberta J., Ernst, Robert K., Chang, Mayland, Melander, Christian
Published in European journal of medicinal chemistry (05.05.2023)
Published in European journal of medicinal chemistry (05.05.2023)
Get full text
Journal Article
Marine sponge alkaloids as a source of anti-bacterial adjuvants
Melander, Roberta J., Liu, Hong-bing, Stephens, Matthew D., Bewley, Carole A., Melander, Christian
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
Get full text
Journal Article