Triple Artemisinin-Based Combination Therapies for Malaria – A New Paradigm?
van der Pluijm, Rob W., Amaratunga, Chanaki, Dhorda, Mehul, Dondorp, Arjen M.
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Published in Trends in parasitology (01.01.2021)
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Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study
Hamilton, William L, Amato, Roberto, van der Pluijm, Rob W, Jacob, Christopher G, Quang, Huynh Hong, Thuy-Nhien, Nguyen Thanh, Hien, Tran Tinh, Hongvanthong, Bouasy, Chindavongsa, Keobouphaphone, Mayxay, Mayfong, Huy, Rekol, Leang, Rithea, Huch, Cheah, Dysoley, Lek, Amaratunga, Chanaki, Suon, Seila, Fairhurst, Rick M, Tripura, Rupam, Peto, Thomas J, Sovann, Yok, Jittamala, Podjanee, Hanboonkunupakarn, Borimas, Pukrittayakamee, Sasithon, Chau, Nguyen Hoang, Imwong, Mallika, Dhorda, Mehul, Vongpromek, Ranitha, Chan, Xin Hui S, Maude, Richard J, Pearson, Richard D, Nguyen, T, Rockett, Kirk, Drury, Eleanor, Gonçalves, Sónia, White, Nicholas J, Day, Nicholas P, Kwiatkowski, Dominic P, Dondorp, Arjen M, Miotto, Olivo
Published in The Lancet infectious diseases (01.09.2019)
Published in The Lancet infectious diseases (01.09.2019)
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Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial
Taylor, Walter R J, Thriemer, Kamala, von Seidlein, Lorenz, Yuentrakul, Prayoon, Assawariyathipat, Thanawat, Assefa, Ashenafi, Auburn, Sarah, Chand, Krisin, Chau, Nguyen Hoang, Cheah, Phaik Yeong, Dong, Le Thanh, Dhorda, Mehul, Degaga, Tamiru Shibru, Devine, Angela, Ekawati, Lenny L, Fahmi, Fahmi, Hailu, Asrat, Hasanzai, Mohammad Anwar, Hien, Tran Tinh, Khu, Htee, Ley, Benedikt, Lubell, Yoel, Marfurt, Jutta, Mohammad, Hussein, Moore, Kerryn A, Naddim, Mohammad Nader, Pasaribu, Ayodhia Pitaloka, Pasaribu, Syahril, Promnarate, Cholrawee, Rahim, Awab Ghulam, Sirithiranont, Pasathron, Solomon, Hiwot, Sudoyo, Herawati, Sutanto, Inge, Thanh, Ngo Viet, Tuyet-Trinh, Nguyen Thi, Waithira, Naomi, Woyessa, Adugna, Yamin, Fazal Yamin, Dondorp, Arjen, Simpson, Julie A, Baird, J Kevin, White, Nicholas J, Day, Nicholas P, Price, Ric N
Published in The Lancet (British edition) (14.09.2019)
Published in The Lancet (British edition) (14.09.2019)
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Numerical Distributions of Parasite Densities During Asymptomatic Malaria
Imwong, Mallika, Stepniewska, Kasia, Tripura, Rupam, Peto, Thomas J., Lwin, Khin Maung, Vihokhern, Benchawan, Wongsaen, Klanarong, von Seidlein, Lorenz, Dhorda, Mehul, Snounou, Georges, Keereecharoen, Lilly, Singhasivanon, Pratap, Sirithiranont, Pasathorn, Chalk, Jem, Nguon, Chea, Day, Nicholas P. J., Nosten, Francois, Dondorp, Arjen, White, Nicholas J.
Published in The Journal of infectious diseases (15.04.2016)
Published in The Journal of infectious diseases (15.04.2016)
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Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker
Tun, Kyaw M, MD, Imwong, Mallika, Dr, Lwin, Khin M, MD, Win, Aye A, MD, Hlaing, Tin M, Prof, Hlaing, Thaung, Prof, Lin, Khin, MD, Kyaw, Myat P, MD, Plewes, Katherine, MD, Faiz, M Abul, Prof, Dhorda, Mehul, PhD, Cheah, Phaik Yeong, PhD, Pukrittayakamee, Sasithon, Prof, Ashley, Elizabeth A, MD, Anderson, Tim J C, PhD, Nair, Shalini, MSc, McDew-White, Marina, MSc, Flegg, Jennifer A, PhD, Grist, Eric P M, PhD, Guerin, Philippe, Prof, Maude, Richard J, MD, Smithuis, Frank, MD, Dondorp, Arjen M, Prof, Day, Nicholas P J, Prof, Nosten, François, Prof, White, Nicholas J, Prof, Woodrow, Charles J, MD
Published in The Lancet infectious diseases (01.04.2015)
Published in The Lancet infectious diseases (01.04.2015)
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Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
Mok, Sachel, Ashley, Elizabeth A., Ferreira, Pedro E., Zhu, Lei, Lin, Zhaoting, Yeo, Tomas, Chotivanich, Kesinee, Imwong, Mallika, Pukrittayakamee, Sasithon, Dhorda, Mehul, Nguon, Chea, Lim, Pharath, Amaratunga, Chanaki, Suon, Seila, Hien, Tran Tinh, Htut, Ye, Faiz, M. Abul, Onyamboko, Marie A., Mayxay, Mayfong, Newton, Paul N., Tripura, Rupam, Woodrow, Charles J., Miotto, Olivo, Kwiatkowski, Dominic P., Nosten, François, Day, Nichoals P. J., Preiser, Peter R., White, Nicholas J., Dondorp, Arjen M., Fairhurst, Rick M., Bozdech, Zbynek
Published in Science (American Association for the Advancement of Science) (23.01.2015)
Published in Science (American Association for the Advancement of Science) (23.01.2015)
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Association of mutations in the Plasmodium falciparum Kelch13 gene ( Pf3D7_1343700 ) with parasite clearance rates after artemisinin-based treatmentsa WWARN individual patient data meta-analysis
Amaratunga, C, Andrianaranjaka, VH, Ashley, E, Bethell, D, Bjorkman, A, Bonnington, CA, Cooper, RA, Dhorda, M, Dondorp, A, Erhart, A
Published in BMC medicine (17.01.2019)
Published in BMC medicine (17.01.2019)
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A Systematic Literature Review of Microscopy Methods Reported in Malaria Clinical Trials
Das, Debashish, Dahal, Prabin, Dhorda, Mehul, Citarella, Barbara Wanjiru, Kennon, Kalynn, Stepniewska, Kasia, Felger, Ingrid, Chappuis, François, Guerin, Philippe J
Published in The American journal of tropical medicine and hygiene (01.03.2021)
Published in The American journal of tropical medicine and hygiene (01.03.2021)
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Triple therapy with artemether–lumefantrine plus amodiaquine versus artemether–lumefantrine alone for artemisinin-resistant, uncomplicated falciparum malaria: an open-label, randomised, multicentre trial
Peto, Thomas J, Tripura, Rupam, Callery, James J, Lek, Dysoley, Nghia, Ho Dang Trung, Nguon, Chea, Thuong, Nguyen Thi Huyen, van der Pluijm, Rob W, Dung, Nguyen Thi Phuong, Sokha, Meas, Van Luong, Vo, Long, Le Thanh, Sovann, Yok, Duanguppama, Jureeporn, Waithira, Naomi, Hoglund, Richard M, Chotsiri, Palang, Chau, Nguyen Hoang, Ruecker, Andrea, Amaratunga, Chanaki, Dhorda, Mehul, Miotto, Olivo, Maude, Richard J, Rekol, Huy, Chotivanich, Kesinee, Tarning, Joel, von Seidlein, Lorenz, Imwong, Mallika, Mukaka, Mavuto, Day, Nicholas P J, Hien, Tran Tinh, White, Nicholas J, Dondorp, Arjen M
Published in The Lancet infectious diseases (01.06.2022)
Published in The Lancet infectious diseases (01.06.2022)
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An inventory of supranational antimicrobial resistance surveillance networks involving low- and middle-income countries since 2000
Ashley, Elizabeth A, Recht, Judith, Chua, Arlene, Dance, David, Dhorda, Mehul, Thomas, Nigel V, Ranganathan, Nisha, Turner, Paul, Guerin, Philippe J, White, Nicholas J, Day, Nicholas P
Published in Journal of antimicrobial chemotherapy (01.07.2018)
Published in Journal of antimicrobial chemotherapy (01.07.2018)
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Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort
Ataide, Ricardo, Ashley, Elizabeth A., Powell, Rosanna, Chan, Jo-Anne, Malloy, Michael J., O’Flaherty, Katherine, Takashima, Eizo, Langer, Christine, Tsuboi, Takafumi, Dondorp, Arjen M., Day, Nicholas P., Dhorda, Mehul, Fairhurst, Rick M., Lim, Pharath, Amaratunga, Chanaki, Pukrittayakamee, Sasithon, Hien, Tran Tinh, Htut, Ye, Mayxay, Mayfong, Faiz, M. Abul, Beeson, James G., Nosten, Francois, Simpson, Julie A., White, Nicholas J., Fowkes, Freya J. I.
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2017)
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Systematic Review and Geospatial Modeling of Molecular Markers of Resistance to Artemisinins and Sulfadoxine-Pyrimethamine in Plasmodium falciparum in India
Nain, Minu, Dhorda, Mehul, Flegg, Jennifer A, Gupta, Apoorv, Harrison, Lucinda E, Singh-Phulgenda, Sauman, Otienoburu, Sabina D, Harriss, Eli, Bharti, Praveen K, Behera, Beauty, Rahi, Manju, Guerin, Philippe J, Sharma, Amit
Published in The American journal of tropical medicine and hygiene (01.05.2024)
Published in The American journal of tropical medicine and hygiene (01.05.2024)
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Artemisinin-resistant malaria in Africa demands urgent action
Dhorda, Mehul, Kaneko, Akira, Komatsu, Ryuichi, Kc, Achyut, Mshamu, Salum, Gesase, Samwel, Kapologwe, Ntuli, Assefa, Ashenafi, Opigo, Jimmy, Adoke, Yeka, Ebong, Chris, Karema, Corine, Uwimana, Aline, Mangara, Jean-Louis Ndikumana, Amaratunga, Chanaki, Peto, Thomas J, Tripura, Rupam, Callery, James J, Adhikari, Bipin, Mukaka, Mavuto, Cheah, Phaik Yeong, Mutesa, Leon, Day, Nicholas P J, Barnes, Karen I, Dondorp, Arjen, Rosenthal, Philip J, White, Nicholas J, von Seidlein, Lorenz
Published in Science (American Association for the Advancement of Science) (19.07.2024)
Published in Science (American Association for the Advancement of Science) (19.07.2024)
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Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial
Taylor, Walter R, Olupot-Olupot, Peter, Onyamboko, Marie A, Peerawaranun, Pimnara, Weere, Winifred, Namayanja, Cate, Onyas, Peter, Titin, Harriet, Baseke, Joy, Muhindo, Rita, Kayembe, Daddy K, Ndjowo, Pauline O, Basara, Benjamin B, Bongo, Georgette S, Okalebo, Charles B, Abongo, Grace, Uyoga, Sophie, Williams, Thomas N, Taya, Chiraporn, Dhorda, Mehul, Tarning, Joel, Dondorp, Arjen M, Waithira, Naomi, Fanello, Caterina, Maitland, Kathryn, Mukaka, Mavuto, Day, Nicholas J P
Published in The Lancet infectious diseases (01.04.2023)
Published in The Lancet infectious diseases (01.04.2023)
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Evolution of Multidrug Resistance in Plasmodium falciparum: a Longitudinal Study of Genetic Resistance Markers in the Greater Mekong Subregion
Imwong, Mallika, Suwannasin, Kanokon, Srisutham, Suttipat, Vongpromek, Ranitha, Promnarate, Cholrawee, Saejeng, Aungkana, Phyo, Aung Pyae, Proux, Stephane, Pongvongsa, Tiengkham, Chea, Nguon, Miotto, Olivo, Tripura, Rupam, Nguyen Hoang, Chau, Dysoley, Lek, Ho Dang Trung, Nghia, Peto, Thomas J, Callery, James J, van der Pluijm, Rob W, Amaratunga, Chanaki, Mukaka, Mavuto, von Seidlein, Lorenz, Mayxay, Mayfong, Thuy-Nhien, Nguyen Thanh, Newton, Paul N, Day, Nicholas P J, Ashley, Elizabeth A, Nosten, Francois H, Smithuis, Frank M, Dhorda, Mehul, White, Nicholas J, Dondorp, Arjen M
Published in Antimicrobial agents and chemotherapy (17.11.2021)
Published in Antimicrobial agents and chemotherapy (17.11.2021)
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Arterolane–piperaquine–mefloquine versus arterolane–piperaquine and artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a single-centre, open-label, randomised, non-inferiority trial
Hamaluba, Mainga, van der Pluijm, Rob W, Weya, Joseph, Njuguna, Patricia, Ngama, Mwanajuma, Kalume, Peter, Mwambingu, Gabriel, Ngetsa, Caroline, Wambua, Juliana, Boga, Mwanamvua, Mturi, Neema, Lal, Altaf A, Khuroo, Arshad, Taylor, Walter R J, Gonçalves, Sónia, Miotto, Olivo, Dhorda, Mehul, Mutinda, Brian, Mukaka, Mavuto, Waithira, Naomi, Hoglund, Richard M, Imwong, Mallika, Tarning, Joel, Day, Nicholas P J, White, Nicholas J, Bejon, Philip, Dondorp, Arjen M
Published in The Lancet infectious diseases (01.10.2021)
Published in The Lancet infectious diseases (01.10.2021)
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The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background
Zhu, Lei, Tripathi, Jaishree, Rocamora, Frances Maureen, Miotto, Olivo, van der Pluijm, Rob, Voss, Till S., Mok, Sachel, Kwiatkowski, Dominic P., Nosten, François, Day, Nicholas P. J., White, Nicholas J., Dondorp, Arjen M., Bozdech, Zbynek
Published in Nature communications (04.12.2018)
Published in Nature communications (04.12.2018)
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