Safety, tolerability, and pharmacokinetics of single and multiple doses of intravenous cixutumumab (IMC-A12), an inhibitor of the insulin-like growth factor-I receptor, administered weekly or every 2 weeks in patients with advanced solid tumors
Higano, C. S., Berlin, J., Gordon, M., LoRusso, P., Tang, S., Dontabhaktuni, A., Schwartz, J. D., Cosaert, J., Mehnert, J. M.
Published in Investigational new drugs (01.04.2015)
Published in Investigational new drugs (01.04.2015)
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Avelumab in patients with previously treated metastatic Merkel cell carcinoma (JAVELIN Merkel 200): updated overall survival data after >5 years of follow-up
D'Angelo, S.P., Bhatia, S., Brohl, A.S., Hamid, O., Mehnert, J.M., Terheyden, P., Shih, K.C., Brownell, I., Lebbé, C., Lewis, K.D., Linette, G.P., Milella, M., Xiong, H., Guezel, G., Nghiem, P.T.
Published in ESMO open (01.12.2021)
Published in ESMO open (01.12.2021)
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60PResponse rates with talimogene laherparepvec (T-VEC) monotherapy in patients (pts) with stage IIIB-IVM1c melanoma previously treated with checkpoint inhibitor (CPI) therapy: Retrospective analysis of two clinical trials
Gogas, H, Gutzmer, R, Malvehy, J, Mehnert, J M, Liu, K, Pickett, C A, Snyder, W, Chesney, J
Published in Annals of oncology (01.12.2018)
Published in Annals of oncology (01.12.2018)
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LBA70Talimogene laherparepvec (T-VEC) in combination (combo) with ipilimumab (ipi) versus ipi alone for advanced melanoma: 3-year landmark analysis of a randomized, open-label, phase II trial
Chesney, J A, Puzanov, I, Collichio, F, Singh, P, Milhem, M, Glaspy, J, Hamid, O, Ross, M I, Friedlander, P, Garbe, C, Logan, T, Hauschild, A, Lebbe, C, Yi, M, Sharma, A, Mehnert, J M
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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1044PPembrolizumab in patients with MSI-H advanced endometrial cancer from the KEYNOTE-158 study
O'Malley, D, Marabelle, A, De Jesus-Acosta, A, Piha-Paul, S A, Arkhipov, A, Longo, F, Motola-Kuba, D, Shapira-Frommer, R, Geva, R, Rimel, B J, Lopez-Martin, J A, Hansen, A R, Mehnert, J M, Chen, X, Jin, F, Norwood, K, Ott, P A
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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A phase II trial of riluzole, an antagonist of metabotropic glutamate receptor (GRM1) signaling, in advanced melanoma
Mehnert, J. M., Wen, Y., Lee, J. H., Dudek, L., Pruski-Clark, L., Shih, W., Chen, S., Goydos, J. S.
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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Journal Article
A phase II trial of gemcitabine (G), carboplatin (C), and sorafenib (S) in patients (pts) with transitional cell carcinoma (TCC): Preliminary safety and outcome
Mehnert, J. M., Mortazavi, A., Stein, M. N., Donadio, A. C., Zelterman, D., McDonough, J. A., Rowen, E., Hoimes, C. J., Gibney, G., Kelly, W. K.
Published in Journal of clinical oncology (01.03.2011)
Published in Journal of clinical oncology (01.03.2011)
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Journal Article
Is there a therapeutic benefit for patients participating in modern phase I trials?
Stein, M. N., Tan, A. R., Mehnert, J. M., Gibbon, D., DiPaola, R. S., Moss, R. A., Poplin, E., Rubin, E. H., Saraiya, B., Kane, M. P., Scott, P., LaRosiliere, M., Camisa, H., Kirin, P., Thomas, C. M., Aisner, J.
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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Phase Ib dose-escalation study of MetMAb, a monovalent antagonist antibody to the receptor MET, in combination with bevacizumab in patients with locally advanced or metastatic solid tumors
Moss, R. A., Bothos, J. G., Filvaroff, E., Merchant, M., Eppler, S., Yu, W., Harris, K., Scott, P., Mehnert, J. M., Patel, P. H.
Published in Journal of clinical oncology (20.05.2010)
Published in Journal of clinical oncology (20.05.2010)
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A phase II trial of riluzole, an antagonist of metabotropic glutamate receptor 1 (GRM1) signaling, in metastatic melanoma
Mehnert, J. M., Lee, J. H., Shirk, J., Bhavsar, D., Anosike, O., Chan, J. L., Shih, W., Chen, S., Goydos, J. S.
Published in Journal of clinical oncology (20.05.2010)
Published in Journal of clinical oncology (20.05.2010)
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Autophagy as a therapeutic target in cancer treatment
Karantza, V., Moss, R. A., Mehnert, J. M., Stein, M. N., Poplin, E., Saraiya, B., Aisner, J., Tan, A. R., White, E., DiPaola, R. S.
Published in Journal of clinical oncology (20.05.2010)
Published in Journal of clinical oncology (20.05.2010)
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VEGF, VEGFR1, and VEGFR2 expression in melanoma
Mehnert, J. M., McCarthy, M. M., Aziz, S. A., Sznol, M., Flaherty, K. T., Camp, R. L., Rimm, D. L., Kluger, H. M.
Published in Journal of clinical oncology (20.06.2007)
Published in Journal of clinical oncology (20.06.2007)
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Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy)
Ascierto, Paolo A, Puzanov, Igor, Agarwala, Sanjiv S, Bifulco, Carlo, Botti, Gerardo, Caracò, Corrado, Ciliberto, Gennaro, Davies, Michael A, Dummer, Reinhard, Ferrone, Soldano, Gajewski, Thomas F, Garbe, Claus, Luke, Jason J, Marincola, Francesco M, Masucci, Giuseppe, Mehnert, Janice M, Mozzillo, Nicola, Palmieri, Giuseppe, Postow, Michael A, Schoenberger, Stephen P, Wang, Ena, Thurin, Magdalena
Published in Journal of translational medicine (21.07.2018)
Published in Journal of translational medicine (21.07.2018)
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Conference Proceeding