Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma
Megquier, Kate, Turner-Maier, Jason, Swofford, Ross, Kim, Jong-Hyuk, Sarver, Aaron L, Wang, Chao, Sakthikumar, Sharadha, Johnson, Jeremy, Koltookian, Michele, Lewellen, Mitzi, Scott, Milcah C, Schulte, Ashley J, Borst, Luke, Tonomura, Noriko, Alfoldi, Jessica, Painter, Corrie, Thomas, Rachael, Karlsson, Elinor K, Breen, Matthew, Modiano, Jaime F, Elvers, Ingegerd, Lindblad-Toh, Kerstin
Published in Molecular cancer research (01.12.2019)
Published in Molecular cancer research (01.12.2019)
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Journal Article
Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics
Rodrigues, Lucas, Watson, Joshua, Feng, Yuan, Lewis, Benjamin, Harvey, Garrett, Post, Gerald, Megquier, Kate, White, Michelle E., Lambert, Lindsay, Miller, Aubrey, Lopes, Christina, Zhao, Shaying
Published in Scientific reports (06.07.2023)
Published in Scientific reports (06.07.2023)
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The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations
Megquier, Kate, Turner-Maier, Jason, Morrill, Kathleen, Li, Xue, Johnson, Jeremy, Karlsson, Elinor K, London, Cheryl A, Gardner, Heather L
Published in PloS one (13.09.2022)
Published in PloS one (13.09.2022)
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Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions
Kim, Jong Hyuk, Megquier, Kate, Thomas, Rachael, Sarver, Aaron L, Song, Jung Min, Kim, Yoon Tae, Cheng, Nuojin, Schulte, Ashley J, Linden, Michael A, Murugan, Paari, Oseth, LeAnn, Forster, Colleen L, Elvers, Ingegerd, Swofford, Ross, Turner-Maier, Jason, Karlsson, Elinor K, Breen, Matthew, Lindblad-Toh, Kerstin, Modiano, Jaime F
Published in Molecular cancer research (01.05.2021)
Published in Molecular cancer research (01.05.2021)
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Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy
Ivansson, Emma L., Megquier, Kate, Kozyrev, Sergey V., Murén, Eva, Körberg, Izabella Baranowska, Swofford, Ross, Koltookian, Michele, Tonomura, Noriko, Zeng, Rong, Kolicheski, Ana L., Hansen, Liz, Katz, Martin L., Johnson, Gayle C., Johnson, Gary S., Coates, Joan R., Lindblad-Toh, Kerstin
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2016)
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Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers
Tonomura, Noriko, Elvers, Ingegerd, Thomas, Rachael, Megquier, Kate, Turner-Maier, Jason, Howald, Cedric, Sarver, Aaron L, Swofford, Ross, Frantz, Aric M, Ito, Daisuke, Mauceli, Evan, Arendt, Maja, Noh, Hyun Ji, Koltookian, Michele, Biagi, Tara, Fryc, Sarah, Williams, Christina, Avery, Anne C, Kim, Jong-Hyuk, Barber, Lisa, Burgess, Kristine, Lander, Eric S, Karlsson, Elinor K, Azuma, Chieko, Modiano, Jaime F, Breen, Matthew, Lindblad-Toh, Kerstin
Published in PLoS genetics (01.02.2015)
Published in PLoS genetics (01.02.2015)
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Ancestry-inclusive dog genomics challenges popular breed stereotypes
Morrill, Kathleen, Hekman, Jessica, Li, Xue, McClure, Jesse, Logan, Brittney, Goodman, Linda, Gao, Mingshi, Dong, Yinan, Alonso, Marjie, Carmichael, Elena, Snyder-Mackler, Noah, Alonso, Jacob, Noh, Hyun Ji, Johnson, Jeremy, Koltookian, Michele, Lieu, Charlie, Megquier, Kate, Swofford, Ross, Turner-Maier, Jason, White, Michelle E, Weng, Zhiping, Colubri, Andrés, Genereux, Diane P, Lord, Kathryn A, Karlsson, Elinor K
Published in Science (American Association for the Advancement of Science) (29.04.2022)
Published in Science (American Association for the Advancement of Science) (29.04.2022)
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Molecular Biology and Evolution of Cancer: From Discovery to Action
Somarelli, Jason A, Gardner, Heather, Cannataro, Vincent L, Gunady, Ella F, Boddy, Amy M, Johnson, Norman A, Fisk, Jeffrey Nicholas, Gaffney, Stephen G, Chuang, Jeffrey H, Li, Sheng, Ciccarelli, Francesca D, Panchenko, Anna R, Megquier, Kate, Kumar, Sudhir, Dornburg, Alex, DeGregori, James, Townsend, Jeffrey P
Published in Molecular biology and evolution (01.02.2020)
Published in Molecular biology and evolution (01.02.2020)
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Lifetime prevalence of malignant and benign tumours in companion dogs: Cross‐sectional analysis of Dog Aging Project baseline survey
Schwartz, Stephen M., Urfer, Silvan R., White, Michelle, Megquier, Kate, Shrager, Sandi, Ruple, Audrey
Published in Veterinary & comparative oncology (01.12.2022)
Published in Veterinary & comparative oncology (01.12.2022)
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Abstract 195: Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma
Kim, Jong Hyuk, Megquier, Kate, Sarver, Aaron L., Thomas, Rachael, Schulte, Ashley J., Wang, Chao, Elvers, Ingegerd, Karlsson, Elinor, Breen, Matthew, Lindblad-Toh, Kerstin, Modiano, Jaime F.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Improving Cancer Drug Discovery by Studying Cancer across the Tree of Life
Somarelli, Jason A, Boddy, Amy M, Gardner, Heather L, DeWitt, Suzanne Bartholf, Tuohy, Joanne, Megquier, Kate, Sheth, Maya U, Hsu, Shiaowen David, Thorne, Jeffrey L, London, Cheryl A, Eward, William C
Published in Molecular biology and evolution (01.01.2020)
Published in Molecular biology and evolution (01.01.2020)
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Identification of genomic alterations with clinical impact in canine splenic hemangiosarcoma
Estabrooks, Timothy, Gurinovich, Anastasia, Pietruska, Jodie, Lewis, Benjamin, Harvey, Garrett, Post, Gerald, Lambert, Lindsay, Miller, Aubrey, Rodrigues, Lucas, White, Michelle E., Lopes, Christina, London, Cheryl A., Megquier, Kate
Published in Veterinary & comparative oncology (01.12.2023)
Published in Veterinary & comparative oncology (01.12.2023)
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Journal Article
Abstract 5357: Mutational and transcriptomic profiling identify distinct angiogenic and inflammatory subtypes of angiosarcoma
Kim, Jong Hyuk, Megquier, Kate, Sarver, Aaron L., Thomas, Rachael, Wang, Chao, Elvers, Ingegerd, Karlsson, Elinor, Breen, Matthew, Lindblad-Toh, Kerstin, Modiano, Jaime F.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the CDKN2A/B Gene Locus as a Major Risk Locus
Letko, Anna, Minor, Katie M, Norton, Elaine M, Marinescu, Voichita D, Drögemüller, Michaela, Ivansson, Emma, Megquier, Kate, Noh, Hyun Ji, Starkey, Mike, Friedenberg, Steven G, Lindblad-Toh, Kerstin, Mickelson, James R, Drögemüller, Cord
Published in Genes (09.12.2021)
Published in Genes (09.12.2021)
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BarkBase: Epigenomic Annotation of Canine Genomes
Megquier, Kate, Genereux, Diane P, Hekman, Jessica, Swofford, Ross, Turner-Maier, Jason, Johnson, Jeremy, Alonso, Jacob, Li, Xue, Morrill, Kathleen, Anguish, Lynne J, Koltookian, Michele, Logan, Brittney, Sharp, Claire R, Ferrer, Lluis, Lindblad-Toh, Kerstin, Meyers-Wallen, Vicki N, Hoffman, Andrew, Karlsson, Elinor K
Published in Genes (07.06.2019)
Published in Genes (07.06.2019)
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Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers: e1004922
Tonomura, Noriko, Elvers, Ingegerd, Thomas, Rachael, Megquier, Kate, Turner-Maier, Jason, Howald, Cedric, Sarver, Aaron L, Swofford, Ross, Frantz, Aric M, Ito, Daisuke, Mauceli, Evan, Arendt, Maja, Noh, Hyun Ji, Koltookian, Michele, Biagi, Tara, Fryc, Sarah, Williams, Christina, Avery, Anne C, Kim, Jong-Hyuk, Barber, Lisa, Burgess, Kristine, Lander, Eric S, Karlsson, Elinor K, Azuma, Chieko, Modiano, Jaime F, Breen, Matthew, Lindblad-Toh, Kerstin
Published in PLoS genetics (01.02.2015)
Published in PLoS genetics (01.02.2015)
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Impact of preanalytical factors on liquid biopsy in the canine cancer model
Megquier, Kate, Husted, Christopher, Rhoades, Justin, White, Michelle E, Genereux, Diane P, Chen, Frances L, Xiong, Kan, Kwon, Euijin, Swofford, Ross, Painter, Corrie, Adalsteinsson, Viktor, London, Cheryl A, Gardner, Heather L, Karlsson, Elinor K
Published in bioRxiv (30.07.2024)
Published in bioRxiv (30.07.2024)
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Journal Article
Identification of genomic alterations with clinical impact in canine splenic hemangiosarcoma
Estabrooks, Timothy, Gurinovich, Anastasia, Pietruska, Jodie, Lewis, Benjamin, Garrett, Harvey, Post, Gerald, Lambert, Lindsay, Lucas Campos Rodrigues, White, Michelle E, Lopes, Christina, London, Cheryl A, Megquier, Kate
Published in bioRxiv (17.11.2022)
Published in bioRxiv (17.11.2022)
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Paper
Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions
Kim, Jong Hyuk, Megquier, Kate, Thomas, Rachael, Sarver, Aaron L, Song, Jung Min, Kim, Yoon Tae, Cheng, Nuojin, Schulte, Ashley J, Linden, Michael A, Murugan, Paari, Oseth, Leann, ster, Colleen L, Elvers, Ingegerd, Swofford, Ross, Turner-Maier, Jason, Karlsson, Elinor K, Breen, Matthew, Lindblad-Toh, Kerstin, Modiano, Jaime F
Published in bioRxiv (16.12.2020)
Published in bioRxiv (16.12.2020)
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