A next generation peripherally restricted Cavα2δ-1 ligand with inhibitory action on Cav2.2 channels and utility in neuropathic pain
Kricek, Franz, Ruf, Christine, Meghani, Premji, Souza, Ivana A., Gandini, Maria A., Zamponi, Gerald W., Skouteris, George
Published in Biomedicine & pharmacotherapy (01.05.2024)
Published in Biomedicine & pharmacotherapy (01.05.2024)
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Journal Article
Identification of a Putative Intracellular Allosteric Antagonist Binding-Site in the CXC Chemokine Receptors 1 and 2
Nicholls, David J, Tomkinson, Nick P, Wiley, Katherine E, Brammall, Anne, Bowers, Lorna, Grahames, Caroline, Gaw, Alasdair, Meghani, Premji, Shelton, Philip, Wright, Tracey J, Mallinder, Philip R
Published in Molecular pharmacology (01.11.2008)
Published in Molecular pharmacology (01.11.2008)
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Journal Article
New Lewis-Basic N-Oxides as Chiral Organocatalysts in Asymmetric Allylation of Aldehydes
Malkov, Andrei V, Bell, Mark, Orsini, Monica, Pernazza, Daniele, Massa, Antonio, Herrmann, Pavel, Meghani, Premji, Kočovský, Pavel
Published in Journal of organic chemistry (12.12.2003)
Published in Journal of organic chemistry (12.12.2003)
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Journal Article
Novel N-Aryl and N-Heteroaryl Sulfamide Synthesis via Palladium Cross Coupling
Alcaraz, Lilian, Bennion, Colin, Morris, James, Meghani, Premji, Thom, Stephen M
Published in Organic letters (05.08.2004)
Published in Organic letters (05.08.2004)
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Journal Article
From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y(2) receptor
Kindon, Nicholas, Davis, Andrew, Dougall, Iain, Dixon, John, Johnson, Timothy, Walters, Iain, Thom, Steve, McKechnie, Kenneth, Meghani, Premji, Stocks, Michael J.
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
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Journal Article
From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y2 receptor
Kindon, Nicholas, Davis, Andrew, Dougall, Iain, Dixon, John, Johnson, Timothy, Walters, Iain, Thom, Steve, McKechnie, Kenneth, Meghani, Premji, Stocks, Michael J.
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
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Journal Article
Discovery and evaluation of a novel monocyclic series of CXCR2 antagonists
Austin, Rupert P., Bennion, Colin, Bonnert, Roger V., Cheema, Lal, Cook, Anthony R., Cox, Rhona J., Ebden, Mark R., Gaw, Alasdair, Grime, Ken, Meghani, Premji, Nicholls, David, Phillips, Caroline, Smith, Neal, Steele, John, Stonehouse, Jeffrey P.
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
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Journal Article
Chiral 2,2‘-Bipyridine-Type N-Monoxides as Organocatalysts in the Enantioselective Allylation of Aldehydes with Allyltrichlorosilane
Malkov, Andrei V, Orsini, Monica, Pernazza, Daniele, Muir, Ken W, Langer, Vratislav, Meghani, Premji, Kočovský, Pavel
Published in Organic letters (21.03.2002)
Published in Organic letters (21.03.2002)
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Journal Article
Synthesis of New Chiral 2,2‘-Bipyridine Ligands and Their Application in Copper-Catalyzed Asymmetric Allylic Oxidation and Cyclopropanation
Malkov, Andrei V, Pernazza, Daniele, Bell, Mark, Bella, Marco, Massa, Antonio, Teplý, Filip, Meghani, Premji, Kočovský, Pavel
Published in Journal of organic chemistry (13.06.2003)
Published in Journal of organic chemistry (13.06.2003)
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Journal Article
From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y 2 receptor
Kindon, Nicholas, Davis, Andrew, Dougall, Iain, Dixon, John, Johnson, Timothy, Walters, Iain, Thom, Steve, McKechnie, Kenneth, Meghani, Premji, Stocks, Michael J
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
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Published in Bioorganic & medicinal chemistry letters (01.11.2017)
Journal Article
GLP-1 GLP-1 RECEPTOR MODULATORS
TAMIYA JUNKO, MOORJANI MANISHA, YEAGER ADAM R, BRAHMACHARY ENUGURTHI, MILLS MARK, MEGHANI PREMJI, FOWLER THOMAS, KNAGGS MICHAEL, MARTINBOROUGH ESTHER, HUANG LIMING, NOVAK ANDREW, BOEHM MARCUS F, GLYNN DANIEL
Year of Publication 11.09.2017
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Year of Publication 11.09.2017
Patent
GLP-1 NOVEL GLP-1 RECEPTOR MODULATORS
TAMIYA JUNKO, MOORJANI MANISHA, FOWLER THOMAS, KNAGGS MICHAEL, MARTINBOROUGH ESTHER, YEAGER ADAM R, HUANG LIMING, BRAHMACHARY ENUGURTHI, NOVAK ANDREW, BOEHM MARCUS F, MEGHANI PREMJI
Year of Publication 12.04.2017
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Year of Publication 12.04.2017
Patent
Lead Generation Using Pharmacophore Mapping and Three-Dimensional Database Searching: Application to Muscarinic M3 Receptor Antagonists
Marriott, David P, Dougall, Iain G, Meghani, Premji, Liu, Yu-Jiang, Flower, Darren R
Published in Journal of medicinal chemistry (26.08.1999)
Published in Journal of medicinal chemistry (26.08.1999)
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Journal Article
NOVEL GLP-1 RECEPTOR MODULATORS
TAMIYA JUNKO, MOORJANI MANISHA, FOWLER THOMAS, KNAGGS MICHAEL, MARTINBOROUGH ESTHER, YEAGER ADAM R, HUANG LIMING, BRAHMACHARY ENUGURTHI, NOVAK ANDREW, BOEHM MARCUS F, MEGHANI PREMJI
Year of Publication 20.04.2016
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Year of Publication 20.04.2016
Patent