Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly
Taş, Karin, Volta, Beatrice Dalla, Lindner, Christina, El Bounkari, Omar, Hille, Kathleen, Tian, Yuan, Puig-Bosch, Xènia, Ballmann, Markus, Hornung, Simon, Ortner, Martin, Prem, Sophia, Meier, Laura, Rammes, Gerhard, Haslbeck, Martin, Weber, Christian, Megens, Remco T. A., Bernhagen, Jürgen, Kapurniotu, Aphrodite
Published in Nature communications (25.08.2022)
Published in Nature communications (25.08.2022)
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Journal Article
Presence of luminal neutrophil extracellular traps in atherosclerosis
Megens, Remco T A, Vijayan, Santosh, Lievens, Dirk, Döring, Yvonne, van Zandvoort, Marc A M J, Grommes, Jochen, Weber, Christian, Soehnlein, Oliver
Published in Thrombosis and haemostasis (01.03.2012)
Published in Thrombosis and haemostasis (01.03.2012)
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Journal Article
An integrated set-up for ex vivo characterisation of biaxial murine artery biomechanics under pulsatile conditions
van der Bruggen, Myrthe M., Reesink, Koen D., Spronck, Paul J. M., Bitsch, Nicole, Hameleers, Jeroen, Megens, Remco T. A., Schalkwijk, Casper G., Delhaas, Tammo, Spronck, Bart
Published in Scientific reports (29.01.2021)
Published in Scientific reports (29.01.2021)
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Journal Article
Tick Saliva Protein Evasin‑3 Allows for Visualization of Inflammation in Arteries through Interactions with CXC-Type Chemokines Deposited on Activated Endothelium
Denisov, Stepan S, Heinzmann, Alexandra C. A, Vajen, Tanja, Vries, Mark H. M, Megens, Remco T. A, Suylen, Dennis, Koenen, Rory R, Post, Mark J, Ippel, Johannes H, Hackeng, Tilman M, Dijkgraaf, Ingrid
Published in Bioconjugate chemistry (18.03.2020)
Published in Bioconjugate chemistry (18.03.2020)
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Journal Article
Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice
Simsekyilmaz, Sakine, Liehn, Elisa A, Weinandy, Stefan, Schreiber, Fabian, Megens, Remco T A, Theelen, Wendy, Smeets, Ralf, Jockenhövel, Stefan, Gries, Thomas, Möller, Martin, Klee, Doris, Weber, Christian, Zernecke, Alma
Published in PloS one (18.05.2016)
Published in PloS one (18.05.2016)
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Journal Article
Hyperlipidemia-Triggered Neutrophilia Promotes Early Atherosclerosis
DRECHSLER, Maik, MEGENS, Remco T. A, VAN ZANDVOORT, Marc, WEBER, Christian, SOEHNLEIN, Oliver
Published in Circulation (New York, N.Y.) (02.11.2010)
Published in Circulation (New York, N.Y.) (02.11.2010)
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Journal Article
MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1
Schober, Andreas, Nazari-Jahantigh, Maliheh, Wei, Yuanyuan, Bidzhekov, Kiril, Gremse, Felix, Grommes, Jochen, Megens, Remco T A, Heyll, Kathrin, Noels, Heidi, Hristov, Michael, Wang, Shusheng, Kiessling, Fabian, Olson, Eric N, Weber, Christian
Published in Nature medicine (01.04.2014)
Published in Nature medicine (01.04.2014)
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Journal Article
ApoE attenuates unresolvable inflammation by complex formation with activated C1q
Yin, Changjun, Ackermann, Susanne, Ma, Zhe, Mohanta, Sarajo K., Zhang, Chuankai, Li, Yuanfang, Nietzsche, Sandor, Westermann, Martin, Peng, Li, Hu, Desheng, Bontha, Sai Vineela, Srikakulapu, Prasad, Beer, Michael, Megens, Remco T. A., Steffens, Sabine, Hildner, Markus, Halder, Luke D., Eckstein, Hans-Henning, Pelisek, Jaroslav, Herms, Jochen, Roeber, Sigrun, Arzberger, Thomas, Borodovsky, Anna, Habenicht, Livia, Binder, Christoph J., Weber, Christian, Zipfel, Peter F., Skerka, Christine, Habenicht, Andreas J. R.
Published in Nature medicine (01.03.2019)
Published in Nature medicine (01.03.2019)
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Journal Article
Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis
DÖRING, Yvonne, MANTHEY, Helga D, DAEMEN, Mat J, LUTGENS, Esther, ZENKE, Martin, BINDER, Christoph J, WEBER, Christian, ZERNECKE, Alma, DRECHSLER, Maik, LIEVENS, Dirk, MEGENS, Remco T. A, SOEHNLEIN, Oliver, BUSCH, Martin, MANCA, Marco, KOENEN, Rory R, PELISEK, Jaroslav
Published in Circulation (New York, N.Y.) (03.04.2012)
Published in Circulation (New York, N.Y.) (03.04.2012)
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Journal Article
Generation of complex bone marrow organoids from human induced pluripotent stem cells
Frenz-Wiessner, Stephanie, Fairley, Savannah D., Buser, Maximilian, Goek, Isabel, Salewskij, Kirill, Jonsson, Gustav, Illig, David, zu Putlitz, Benedicta, Petersheim, Daniel, Li, Yue, Chen, Pin-Hsuan, Kalauz, Martina, Conca, Raffaele, Sterr, Michael, Geuder, Johanna, Mizoguchi, Yoko, Megens, Remco T. A., Linder, Monika I., Kotlarz, Daniel, Rudelius, Martina, Penninger, Josef M., Marr, Carsten, Klein, Christoph
Published in Nature methods (01.05.2024)
Published in Nature methods (01.05.2024)
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Journal Article
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
Lacy, Michael, Bürger, Christina, Shami, Annelie, Ahmadsei, Maiwand, Winkels, Holger, Nitz, Katrin, van Tiel, Claudia M., Seijkens, Tom T. P., Kusters, Pascal J. H., Karshovka, Ela, Prange, Koen H. M., Wu, Yuting, Brouns, Sanne L. N., Unterlugauer, Sigrid, Kuijpers, Marijke J. E., Reiche, Myrthe E., Steffens, Sabine, Edsfeldt, Andreas, Megens, Remco T. A., Heemskerk, Johan W. M., Goncalves, Isabel, Weber, Christian, Gerdes, Norbert, Atzler, Dorothee, Lutgens, Esther
Published in Nature communications (18.06.2021)
Published in Nature communications (18.06.2021)
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Journal Article
Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis
Duchene, Johan, Novitzky-Basso, Igor, Thiriot, Aude, Casanova-Acebes, Maria, Bianchini, Mariaelvy, Etheridge, S Leah, Hub, Elin, Nitz, Katrin, Artinger, Katharina, Eller, Kathrin, Caamaño, Jorge, Rülicke, Thomas, Moss, Paul, Megens, Remco T A, von Andrian, Ulrich H, Hidalgo, Andres, Weber, Christian, Rot, Antal
Published in Nature immunology (01.07.2017)
Published in Nature immunology (01.07.2017)
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Journal Article
Endothelial Junctional Adhesion Molecule-A Guides Monocytes Into Flow-Dependent Predilection Sites of Atherosclerosis
Schmitt, Martin M.N, Megens, Remco T.A, Zernecke, Alma, Bidzhekov, Kiril, van den Akker, Nynke M, Rademakers, Timo, van Zandvoort, Marc A, Hackeng, Tilman M, Koenen, Rory R, Weber, Christian
Published in Circulation (New York, N.Y.) (07.01.2014)
Published in Circulation (New York, N.Y.) (07.01.2014)
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Journal Article
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis
Seijkens, Tom T.P., van Tiel, Claudia M., Kusters, Pascal J.H., Atzler, Dorothee, Soehnlein, Oliver, Zarzycka, Barbara, Aarts, Suzanne A.B.M., Lameijer, Marnix, Gijbels, Marion J., Beckers, Linda, den Toom, Myrthe, Slütter, Bram, Kuiper, Johan, Duchene, Johan, Aslani, Maria, Megens, Remco T.A., van ‘t Veer, Cornelis, Kooij, Gijs, Schrijver, Roy, Hoeksema, Marten A., Boon, Louis, Fay, Francois, Tang, Jun, Baxter, Samantha, Jongejan, Aldo, Moerland, Perry D., Vriend, Gert, Bleijlevens, Boris, Fisher, Edward A., Duivenvoorden, Raphael, Gerdes, Norbert, de Winther, Menno P.J., Nicolaes, Gerry A., Mulder, Willem J.M., Weber, Christian, Lutgens, Esther
Published in Journal of the American College of Cardiology (06.02.2018)
Published in Journal of the American College of Cardiology (06.02.2018)
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Journal Article
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting
Kontos, Christos, El Bounkari, Omar, Krammer, Christine, Sinitski, Dzmitry, Hille, Kathleen, Zan, Chunfang, Yan, Guangyao, Wang, Sijia, Gao, Ying, Brandhofer, Markus, Megens, Remco T. A., Hoffmann, Adrian, Pauli, Jessica, Asare, Yaw, Gerra, Simona, Bourilhon, Priscila, Leng, Lin, Eckstein, Hans-Henning, Kempf, Wolfgang E., Pelisek, Jaroslav, Gokce, Ozgun, Maegdefessel, Lars, Bucala, Richard, Dichgans, Martin, Weber, Christian, Kapurniotu, Aphrodite, Bernhagen, Jürgen
Published in Nature communications (25.11.2020)
Published in Nature communications (25.11.2020)
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Journal Article
Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium
Gencer, Selin, Döring, Yvonne, Jansen, Yvonne, Bayasgalan, Soyolmaa, Yan, Yi, Bianchini, Mariaelvy, Cimen, Ismail, Müller, Madeleine, Peters, Linsey J. F., Megens, Remco T. A., von Hundelshausen, Philipp, Duchene, Johan, Lemnitzer, Patricia, Soehnlein, Oliver, Weber, Christian, van der Vorst, Emiel P. C.
Published in Basic research in cardiology (01.12.2022)
Published in Basic research in cardiology (01.12.2022)
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Journal Article
Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis
Schmitz, Corinna, Noels, Heidi, El Bounkari, Omar, Straussfeld, Eva, Megens, Remco T A, Sternkopf, Marieke, Alampour-Rajabi, Setareh, Krammer, Christine, Tilstam, Pathricia V, Gerdes, Norbert, Bürger, Christina, Kapurniotu, Aphrodite, Bucala, Richard, Jankowski, Joachim, Weber, Christian, Bernhagen, Jürgen
Published in The FASEB journal (01.08.2018)
Published in The FASEB journal (01.08.2018)
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Journal Article
RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/β-catenin signaling in human mesenchymal stem cells
Mahl, Christian, Egea, Virginia, Megens, Remco T. A., Pitsch, Thomas, Santovito, Donato, Weber, Christian, Ries, Christian
Published in Cellular and molecular life sciences : CMLS (01.04.2016)
Published in Cellular and molecular life sciences : CMLS (01.04.2016)
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Journal Article
Neutrophil-Derived Cathelicidin Promotes Adhesion of Classical Monocytes
Wantha, Sarawuth, Alard, Jean-Eric, Megens, Remco T.A, van der Does, Anne M, Döring, Yvonne, Drechsler, Maik, Pham, Christine T.N, Wang, Ming-Wei, Wang, Ji-Min, Gallo, Richard L, von Hundelshausen, Philipp, Lindbom, Lennart, Hackeng, Tilman, Weber, Christian, Soehnlein, Oliver
Published in Circulation research (01.03.2013)
Published in Circulation research (01.03.2013)
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