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Chemical synthesis of linear ADP-ribose oligomers up to pentamer and their binding to the oncogenic helicase ALC1
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Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells
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Combined Phosphoramidite‐Phosphodiester Reagents for the Synthesis of Methylene Bisphosphonates
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Published in Angewandte Chemie International Edition (06.03.2017)
Published in Angewandte Chemie International Edition (06.03.2017)
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Simplified Monopalmitoyl Toll‐like Receptor 2 Ligand Mini‐UPam for Self‐Adjuvanting Neoantigen‐Based Synthetic Cancer Vaccines
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Published in Chembiochem : a European journal of chemical biology (06.04.2021)
Published in Chembiochem : a European journal of chemical biology (06.04.2021)
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C‑Mannosyl Lysine for Solid Phase Assembly of Mannosylated Peptide Conjugate Cancer Vaccines
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Bioorthogonal Deprotection on the Dendritic Cell Surface for Chemical Control of Antigen Cross-Presentation
Pawlak, Joanna B., Gential, Geoffroy P. P., Ruckwardt, Tracy J., Bremmers, Jessica S., Meeuwenoord, Nico J., Ossendorp, Ferry A., Overkleeft, Herman S., Filippov, Dmitri V., van Kasteren, Sander I.
Published in Angewandte Chemie International Edition (04.05.2015)
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Synthesis of C‐Glycosyl Amino Acid Building Blocks Suitable for the Solid‐Phase Synthesis of Multivalent Glycopeptide Mimics
Reintjens, Niels R. M., Koemans, Tony S., Zilverschoon, Nick, Castelli, Riccardo, Cordfunke, Robert A., Drijfhout, Jan Wouter, Meeuwenoord, Nico J., Overkleeft, Herman S., Filippov, Dmitri V., Marel, Gijsbert A., Codée, Jeroen D. C.
Published in European journal of organic chemistry (31.08.2020)
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Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates
Zom, Gijs G, Khan, Selina, Britten, Cedrik M, Sommandas, Vinod, Camps, Marcel G M, Loof, Nikki M, Budden, Christina F, Meeuwenoord, Nico J, Filippov, Dmitri V, van der Marel, Gijsbert A, Overkleeft, Hermen S, Melief, Cornelis J M, Ossendorp, Ferry
Published in Cancer immunology research (01.08.2014)
Published in Cancer immunology research (01.08.2014)
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Multivalent, Stabilized Mannose‐6‐Phosphates for the Targeted Delivery of Toll‐Like Receptor Ligands and Peptide Antigens
Reintjens, Niels R. M., Tondini, Elena, Vis, Christopher, McGlinn, Toroa, Meeuwenoord, Nico J., Hogervorst, Tim P., Overkleeft, Herman S., Filippov, Dmitri V., Marel, Gijsbert A., Ossendorp, Ferry, Codée, Jeroen D. C.
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Published in Chembiochem : a European journal of chemical biology (15.01.2021)
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van Delft, Pieter, Meeuwenoord, Nico J, Hoogendoorn, Sascha, Dinkelaar, Jasper, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V
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Published in Organic letters (03.12.2010)
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Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions
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TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients
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Published in Oncotarget (11.10.2016)
Published in Oncotarget (11.10.2016)
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Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG
van den Boorn, Jasper G, Konijnenberg, Debby, Tjin, Esther P M, Picavet, Daisy I, Meeuwenoord, Nico J, Filippov, Dmitri V, van der Veen, J P Wietze, Bos, Jan D, Melief, Cornelis J M, Luiten, Rosalie M
Published in PloS one (13.05.2010)
Published in PloS one (13.05.2010)
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