Development of transient radioresistance during fractionated irradiation in vitro
van den Berg, Jaap, Castricum, Kitty C.M., Meel, Michaël H., Goedegebuure, Ruben S.A., Lagerwaard, Frank J., Slotman, Ben J., Hulleman, Esther, Thijssen, Victor L.J.L.
Published in Radiotherapy and oncology (01.07.2020)
Published in Radiotherapy and oncology (01.07.2020)
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Journal Article
Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin
Metselaar, Dennis S., Meel, Michaël H., Benedict, Bente, Waranecki, Piotr, Koster, Jan, Kaspers, Gertjan J.L., Hulleman, Esther
Published in EBioMedicine (01.12.2019)
Published in EBioMedicine (01.12.2019)
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Journal Article
Culture methods of diffuse intrinsic pontine glioma cells determine response to targeted therapies
Meel, Michaël H., Sewing, A.Charlotte P., Waranecki, Piotr, Metselaar, Dennis S., Wedekind, Laurine E., Koster, Jan, van Vuurden, Dannis G., Kaspers, Gertjan J.L., Hulleman, Esther
Published in Experimental cell research (15.11.2017)
Published in Experimental cell research (15.11.2017)
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Journal Article
Multiregional Tumor Drug-Uptake Imaging by PET and Microvascular Morphology in End-Stage Diffuse Intrinsic Pontine Glioma
Veldhuijzen van Zanten, Sophie E M, Sewing, A Charlotte P, van Lingen, Arthur, Hoekstra, Otto S, Wesseling, Pieter, Meel, Michaël H, van Vuurden, Dannis G, Kaspers, Gertjan J L, Hulleman, Esther, Bugiani, Marianna
Published in Journal of Nuclear Medicine (01.04.2018)
Published in Journal of Nuclear Medicine (01.04.2018)
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Journal Article
Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
Metselaar, Dennis S., Meel, Michaël H., Goulding, Joshua R., du Chatinier, Aimeé, Rigamonti, Leyla, Waranecki, Piotr, Geisemeyer, Neal, de Gooijer, Mark C., Breur, Marjolein, Koster, Jan, Veldhuijzen van Zanten, Sophie E.M., Bugiani, Marianna, Franke, Niels E., Reddy, Alyssa, Wesseling, Pieter, Kaspers, Gertjan J.L., Hulleman, Esther
Published in Cell reports. Medicine (17.09.2024)
Published in Cell reports. Medicine (17.09.2024)
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Journal Article
Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma
Sewing, A Charlotte P, Lagerweij, Tonny, van Vuurden, Dannis G, Meel, Michaël H, Veringa, Susanna J E, Carcaboso, Angel M, Gaillard, Pieter J, Peter Vandertop, W, Wesseling, Pieter, Noske, David, Kaspers, Gertjan J L, Hulleman, Esther
Published in Journal of neurosurgery. Pediatrics (01.05.2017)
Published in Journal of neurosurgery. Pediatrics (01.05.2017)
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Journal Article
An efficient method for the transduction of primary pediatric glioma neurospheres
Meel, Michaël H., Metselaar, Dennis S., Waranecki, Piotr, Kaspers, Gertjan J.L., Hulleman, Esther
Published in MethodsX (01.01.2018)
Published in MethodsX (01.01.2018)
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Journal Article
Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma
Meel, Michaël H, de Gooijer, Mark C, Metselaar, Dennis S, Sewing, A Charlotte P, Zwaan, Kenn, Waranecki, Piotr, Breur, Marjolein, Buil, Levi C M, Lagerweij, Tonny, Wedekind, Laurine E, Twisk, Jos W R, Koster, Jan, Hashizume, Rintaro, Raabe, Eric H, Montero Carcaboso, Ángel, Bugiani, Marianna, Phoenix, Timothy N, van Tellingen, Olaf, van Vuurden, Dannis G, Kaspers, Gertjan J L, Hulleman, Esther
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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Journal Article
MELK Inhibition in Diffuse Intrinsic Pontine Glioma
Meel, Michaël H, de Gooijer, Mark C, Guillén Navarro, Miriam, Waranecki, Piotr, Breur, Marjolein, Buil, Levi C M, Wedekind, Laurine E, Twisk, Jos W R, Koster, Jan, Hashizume, Rintaro, Raabe, Eric H, Montero Carcaboso, Angel, Bugiani, Marianna, van Tellingen, Olaf, van Vuurden, Dannis G, Kaspers, Gertjan J L, Hulleman, Esther
Published in Clinical cancer research (15.11.2018)
Published in Clinical cancer research (15.11.2018)
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Journal Article
MEK/MELK inhibition and blood–brain barrier deficiencies in atypical teratoid/rhabdoid tumors
Meel, Michaël H, Guillén Navarro, Miriam, de Gooijer, Mark C, Metselaar, Dennis S, Waranecki, Piotr, Breur, Marjolein, Lagerweij, Tonny, Wedekind, Laurine E, Koster, Jan, van de Wetering, Marianne D, Schouten-van Meeteren, Netteke, Aronica, Eleonora, van Tellingen, Olaf, Bugiani, Marianna, Phoenix, Timothy N, Kaspers, Gertjan J L, Hulleman, Esther
Published in Neuro-oncology (Charlottesville, Va.) (11.01.2020)
Published in Neuro-oncology (Charlottesville, Va.) (11.01.2020)
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Journal Article
AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma
Metselaar, Dennis S., du Chatinier, Aimée, Meel, Michaël H., ter Huizen, Giovanna, Waranecki, Piotr, Goulding, Joshua R., Bugiani, Marianna, Koster, Jan, Kaspers, Gertjan J.L., Hulleman, Esther
Published in iScience (17.06.2022)
Published in iScience (17.06.2022)
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Journal Article
Normal hematopoietic stem cells within the AML bone marrow have a distinct and higher ALDH activity level than co-existing leukemic stem cells
Schuurhuis, Gerrit J, Meel, Michael H, Wouters, Floris, Min, Lisa A, Terwijn, Monique, de Jonge, Nick A, Kelder, Angele, Snel, Alexander N, Zweegman, Sonja, Ossenkoppele, Gert J, Smit, Linda
Published in PloS one (11.11.2013)
Published in PloS one (11.11.2013)
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Journal Article
Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma
du Chatinier, Aimée, Meel, Michaël H, Das, Arvid I, Metselaar, Dennis S, Waranecki, Piotr, Bugiani, Marianna, Breur, Marjolein, Simonds, Erin F, Lu, Edbert D, Weiss, William A, Garcia Vallejo, Juan J, Hoving, Eelco W, Phoenix, Timothy N, Hulleman, Esther
Published in Neuro-oncology advances (01.01.2022)
Published in Neuro-oncology advances (01.01.2022)
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Journal Article
International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma
Tsoli, Maria, Shen, Han, Mayoh, Chelsea, Franshaw, Laura, Ehteda, Anahid, Upton, Danielle, Carvalho, Diana, Vinci, Maria, Meel, Michael H., van Vuurden, Dannis, Plessier, Alexander, Castel, David, Drissi, Rachid, Farrell, Michael, Cryan, Jane, Crimmins, Darach, Caird, John, Pears, Jane, Francis, Stephanie, Ludlow, Louise E. A., Carai, Andrea, Mastronuzzi, Angela, Liu, Bing, Hansford, Jordan, Gottardo, Nick, Hassall, Tim, Kirby, Maria, Fouladi, Maryam, Hawkins, Cynthia, Monje, Michelle, Grill, Jacques, Jones, Chris, Hulleman, Esther, Ziegler, David S.
Published in Journal of neuro-oncology (01.01.2019)
Published in Journal of neuro-oncology (01.01.2019)
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Journal Article
DIPG-21. PRECLINICAL ASSESSMENT OF A MULTIMODAL TREATMENT APPROACH WITH GIVINOSTAT, PAXALISIB, AND RADIOTHERAPY FOR DIFFUSE MIDLINE GLIOMA (DMG)
du Chatinier, Aimée, Meel, Michaël H, Waranecki, Piotr, Metselaar, Dennis S, Hulleman, Esther
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles
Vazaios, Konstantinos, Stavrakaki, Εftychia, Vogelezang, Lisette B., Ju, Jie, Waranecki, Piotr, Metselaar, Dennis S., Meel, Michaël H., Kemp, Vera, van den Hoogen, Bernadette G., Hoeben, Rob C., Chiocca, E. Antonio, Goins, William F., Stubbs, Andrew, Li, Yunlei, Alonso, Marta M., Calkoen, Friso G., Hulleman, Esther, van der Lugt, Jasper, Lamfers, Martine L.M.
Published in Molecular Therapy Oncology (20.06.2024)
Published in Molecular Therapy Oncology (20.06.2024)
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Journal Article
Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma
Tsoli, Maria, Shen, Han, Mayoh, Chelsea, Franshaw, Laura, Ehteda, Anahid, Upton, Dannielle, Carvalho, Diana, Vinci, Maria, Meel, Michael H., van Vuurden, Dannis, Plessier, Alexandre, Castel, David, Drissi, Rachid, Farrell, Michael, Cryan, Jane, Crimmins, Darach, Caird, John, Pears, Jane, Francis, Stephanie, Ludlow, Louise E. A., Carai, Andrea, Mastronuzzi, Angela, Liu, Bing, Hansford, Jordan, Gottardo, Nicholas G., Hassall, Tim, Kirby, Maria, Fouladi, Maryam, Hawkins, Cynthia, Monje, Michelle, Grill, Jacques, Jones, Chris, Hulleman, Esther, Ziegler, David S.
Published in Journal of neuro-oncology (01.01.2019)
Published in Journal of neuro-oncology (01.01.2019)
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Journal Article