Living Without Creatine: Unchanged Exercise Capacity and Response to Chronic Myocardial Infarction in Creatine-Deficient Mice
Lygate, Craig A, Aksentijevic, Dunja, Dawson, Dana, ten Hove, Michiel, Phillips, Darci, de Bono, Joseph P, Medway, Debra J, Sebag-Montefiore, Liam, Hunyor, Imre, Channon, Keith M, Clarke, Kieran, Zervou, Sevasti, Watkins, Hugh, Balaban, Robert S, Neubauer, Stefan
Published in Circulation research (15.03.2013)
Published in Circulation research (15.03.2013)
Get full text
Journal Article
Refined approach for quantification of in vivo ischemia-reperfusion injury in the mouse heart
Bohl, Steffen, Medway, Debra J, Schulz-Menger, Jeanette, Schneider, Jurgen E, Neubauer, Stefan, Lygate, Craig A
Published in American journal of physiology. Heart and circulatory physiology (01.12.2009)
Published in American journal of physiology. Heart and circulatory physiology (01.12.2009)
Get full text
Journal Article
Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction
LYGATE, Craig A, BOHL, Steffen, CLARKE, Kieran, WATKINS, Hugh, SCHNEIDER, Jürgen E, NEUBAUER, Stefan, TEN HOVE, Michiel, FALLER, Kiterie M. E, OSTROWSKI, Philip J, ZERVOU, Sevasti, MEDWAY, Debra J, AKSENTIJEVIC, Dunja, SEBAG-MONTEFIORE, Liam, WALLIS, Julie
Published in Cardiovascular research (01.12.2012)
Published in Cardiovascular research (01.12.2012)
Get full text
Journal Article
Myocardial infarction causes inflammation and leukocyte recruitment at remote sites in the myocardium and in the renal glomerulus
Ruparelia, Neil, Digby, Janet E., Jefferson, Andrew, Medway, Debra J., Neubauer, Stefan, Lygate, Craig A., Choudhury, Robin P.
Published in Inflammation research (01.05.2013)
Published in Inflammation research (01.05.2013)
Get full text
Journal Article
Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart
Faller, Kiterie M E, Medway, Debra J, Aksentijevic, Dunja, Sebag-Montefiore, Liam, Schneider, Jürgen E, Lygate, Craig A, Neubauer, Stefan
Published in PloS one (18.06.2013)
Published in PloS one (18.06.2013)
Get full text
Journal Article
A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis
Zervou, Sevasti, Ray, Tanmoy, Sahgal, Natasha, Sebag-Montefiore, Liam, Cross, Rebecca, Medway, Debra J, Ostrowski, Philip J, Neubauer, Stefan, Lygate, Craig A
Published in American journal of physiology: endocrinology and metabolism (15.07.2013)
Published in American journal of physiology: endocrinology and metabolism (15.07.2013)
Get full text
Journal Article
Advanced methods for quantification of infarct size in mice using three-dimensional high-field late gadolinium enhancement MRI
Bohl, Steffen, Lygate, Craig A, Barnes, Hannah, Medway, Debra, Stork, Lee-Anne, Schulz-Menger, Jeanette, Neubauer, Stefan, Schneider, Jurgen E
Published in American journal of physiology. Heart and circulatory physiology (01.04.2009)
Published in American journal of physiology. Heart and circulatory physiology (01.04.2009)
Get full text
Journal Article
Accelerating global left-ventricular function assessment in mice using reduced slice acquisition and three-dimensional guide-point modelling
Young, Alistair A, Medway, Debra J, Lygate, Craig A, Neubauer, Stefan, Schneider, Jürgen E
Published in Journal of cardiovascular magnetic resonance (14.09.2011)
Published in Journal of cardiovascular magnetic resonance (14.09.2011)
Get full text
Journal Article
Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age
Lygate, Craig A., Medway, Debra J., Ostrowski, Philip J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Hunyor, Imre, Zervou, Sevasti, Schneider, Jurgen E., Neubauer, Stefan
Published in Basic research in cardiology (01.09.2012)
Published in Basic research in cardiology (01.09.2012)
Get full text
Journal Article
High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes
Aksentijević, Dunja, Lygate, Craig A., Makinen, Kimmo, Zervou, Sevasti, Sebag-Montefiore, Liam, Medway, Debra, Barnes, Hannah, Schneider, Jurgen E., Neubauer, Stefan
Published in European journal of heart failure (01.12.2010)
Published in European journal of heart failure (01.12.2010)
Get full text
Journal Article
Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background
Lygate, Craig A, Hunyor, Imre, Medway, Debra, de Bono, Joe P, Dawson, Dana, Wallis, Julie, Sebag-Montefiore, Liam, Neubauer, Stefan
Published in Journal of molecular and cellular cardiology (01.01.2009)
Published in Journal of molecular and cellular cardiology (01.01.2009)
Get full text
Journal Article
Accurate infarct-size measurements from accelerated, compressed sensing reconstructed cine-MRI images in mouse hearts
Wech, Tobias, Medway, Debra, Lygate, Craig A, Neubauer, Stefan, Köstler, Herbert, Schneider, Jurgen E
Published in Journal of cardiovascular magnetic resonance (01.02.2012)
Published in Journal of cardiovascular magnetic resonance (01.02.2012)
Get full text
Journal Article
Metabolic Inflexibility of Malonyl CoA Decarboxylase (MCD) Knockout Mice Leads to Cardiac Remodelling and High Mortality During Peri-Weaning Period
Aksentijevic, Dunja, Medway, Debra J., Sebag-Montefiore, Liam, Zervou, Sevasti, Douglas, Gillian, Lopaschuk, Gary D., Neubauer, Stefan, Lygate, Craig A.
Published in Biophysical journal (28.01.2014)
Published in Biophysical journal (28.01.2014)
Get full text
Journal Article
Refined approach for quantification of in vivo ischemia-reperfusion injury in the mouse heart
BOHL, Steffen, MEDWAY, Debra J, SCHULZ-MENGER, Jeanette, SCHNEIDER, Jurgen E, NEUBAUER, Stefan, LYGATE, Craig A
Published in American journal of physiology. Heart and circulatory physiology (2009)
Get full text
Published in American journal of physiology. Heart and circulatory physiology (2009)
Journal Article
Ultra-fast and accurate assessment of cardiac function in rats using accelerated MRI at 9.4 Tesla
Schneider, Jürgen E., Lanz, Titus, Barnes, Hannah, Medway, Debra, Stork, Lee-Anne, Lygate, Craig A., Smart, Sean, Griswold, Mark A., Neubauer, Stefan
Published in Magnetic resonance in medicine (01.03.2008)
Published in Magnetic resonance in medicine (01.03.2008)
Get full text
Journal Article
Advanced methods for quantification of infarct size in mice using three-dimensional high-field late gadolinium enhancement MRI
BOHL, Steffen, LYGATE, Craig A, BARNES, Hannah, MEDWAY, Debra, STORK, Lee-Anne, SCHULZ-MENGER, Jeanette, NEUBAUER, Stefan, SCHNEIDER, Jurgen E
Published in American journal of physiology. Heart and circulatory physiology (2009)
Get full text
Published in American journal of physiology. Heart and circulatory physiology (2009)
Journal Article
Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart. e66461
Faller, Kiterie ME, Medway, Debra J, Aksentijevic, Dunja, Sebag-Montefiore, Liam, Schneider, Juergen E, Lygate, Craig A, Neubauer, Stefan
Published in PloS one (01.06.2013)
Published in PloS one (01.06.2013)
Get full text
Journal Article
Heart Failure and Altered Cardiac Energetics—A New Mouse Model for Inducible Sarcomeric Mitochondrial Creatine Kinase (Mt-CK)
Hunyor, Imre, Makinen, Kimmo, Davies, Ben, Medway, Debra, Lygate, Craig, Isbrandt, Dirk, Neubauer, Stefan
Published in Heart, lung & circulation (2009)
Published in Heart, lung & circulation (2009)
Get full text
Journal Article