Critical roles of protein disulfide isomerases in balancing proteostasis in the nervous system
Medinas, Danilo B., Rozas, Pablo, Hetz, Claudio
Published in The Journal of biological chemistry (01.07.2022)
Published in The Journal of biological chemistry (01.07.2022)
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Journal Article
Proteostasis disturbance in amyotrophic lateral sclerosis
Medinas, Danilo B, Valenzuela, Vicente, Hetz, Claudio
Published in Human molecular genetics (01.10.2017)
Published in Human molecular genetics (01.10.2017)
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Journal Article
Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis
Medinas, Danilo B., Rozas, Pablo, Traub, Francisca Martínez, Woehlbier, Ute, Brown, Robert H., Bosco, Daryl A., Hetz, Claudio
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2018)
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Journal Article
IRE1 signaling exacerbates Alzheimer’s disease pathogenesis
Duran-Aniotz, Claudia, Cornejo, Victor Hugo, Espinoza, Sandra, Ardiles, Álvaro O., Medinas, Danilo B., Salazar, Claudia, Foley, Andrew, Gajardo, Ivana, Thielen, Peter, Iwawaki, Takao, Scheper, Wiep, Soto, Claudio, Palacios, Adrian G., Hoozemans, Jeroen J. M., Hetz, Claudio
Published in Acta neuropathologica (01.09.2017)
Published in Acta neuropathologica (01.09.2017)
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Journal Article
The ER proteostasis network in ALS: Determining the differential motoneuron vulnerability
Rozas, Pablo, Bargsted, Leslie, Martínez, Francisca, Hetz, Claudio, Medinas, Danilo B.
Published in Neuroscience letters (01.01.2017)
Published in Neuroscience letters (01.01.2017)
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Journal Article
Editorial: Restoring endoplasmic reticulum proteostasis to treat neurological disorders
Medinas, Danilo B, Arshad, Najla, Parakh, Sonam, Miyamoto, Sayuri, Zambelli, Vanessa Olzon
Published in Frontiers in pharmacology (09.03.2023)
Published in Frontiers in pharmacology (09.03.2023)
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Journal Article
β-catenin aggregation in models of ALS motor neurons: GSK3β inhibition effect and neuronal differentiation
Pinto, Cristina, Medinas, Danilo B., Fuentes-Villalobos, Francisco, Maripillán, Jaime, Castro, Ariel F., Martínez, Agustín D., Osses, Nelson, Hetz, Claudio, Henríquez, Juan P.
Published in Neurobiology of disease (01.10.2019)
Published in Neurobiology of disease (01.10.2019)
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Journal Article
Editorial: Protein Misfolding and Proteostasis Impairment in Aging and Neurodegeneration: From Spreading Studies to Therapeutic Approaches
Duran-Aniotz, Claudia, Moreno-Gonzalez, Ines, Medinas, Danilo B, Morales, Rodrigo
Published in Frontiers in aging neuroscience (09.02.2022)
Published in Frontiers in aging neuroscience (09.02.2022)
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Journal Article
The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasis
Duran-Aniotz, Claudia, Poblete, Natalia, Rivera-Krstulovic, Catalina, Ardiles, Álvaro O., Díaz-Hung, Mei Li, Tamburini, Giovanni, Sabusap, Carleen Mae P., Gerakis, Yannis, Cabral-Miranda, Felipe, Diaz, Javier, Fuentealba, Matias, Arriagada, Diego, Muñoz, Ernesto, Espinoza, Sandra, Martinez, Gabriela, Quiroz, Gabriel, Sardi, Pablo, Medinas, Danilo B., Contreras, Darwin, Piña, Ricardo, Lourenco, Mychael V., Ribeiro, Felipe C., Ferreira, Sergio T., Rozas, Carlos, Morales, Bernardo, Plate, Lars, Gonzalez-Billault, Christian, Palacios, Adrian G., Hetz, Claudio
Published in Molecular therapy (05.07.2023)
Published in Molecular therapy (05.07.2023)
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Journal Article
ER stress links aging to sporadic ALS
Medinas, Danilo B, Cabral-Miranda, Felipe, Hetz, Claudio
Published in Aging (Albany, NY.) (05.01.2019)
Published in Aging (Albany, NY.) (05.01.2019)
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Journal Article
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging
Cabral‐Miranda, Felipe, Tamburini, Giovanni, Martinez, Gabriela, Ardiles, Alvaro O, Medinas, Danilo B, Gerakis, Yannis, Hung, Mei‐Li Diaz, Vidal, René, Fuentealba, Matias, Miedema, Tim, Duran‐Aniotz, Claudia, Diaz, Javier, Ibaceta‐Gonzalez, Cristobal, Sabusap, Carleen M, Bermedo‐Garcia, Francisca, Mujica, Paula, Adamson, Stuart, Vitangcol, Kaitlyn, Huerta, Hernan, Zhang, Xu, Nakamura, Tomohiro, Sardi, Sergio Pablo, Lipton, Stuart A, Kennedy, Brian K, Henriquez, Juan Pablo, Cárdenas, J Cesar, Plate, Lars, Palacios, Adrian G, Hetz, Claudio
Published in The EMBO journal (17.11.2022)
Published in The EMBO journal (17.11.2022)
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Journal Article
The carbonate radical and related oxidants derived from bicarbonate buffer
Medinas, Danilo B, Cerchiaro, Giselle, Trindade, Daniel F, Augusto, Ohara
Published in IUBMB life (2007)
Published in IUBMB life (2007)
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Journal Article
Emerging roles of endoplasmic reticulum proteostasis in brain development
Vásquez, Giselle Espinosa, Medinas, Danilo B., Urra, Hery, Hetz, Claudio
Published in Cells & development (01.06.2022)
Published in Cells & development (01.06.2022)
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Journal Article
ER Dysfunction and Protein Folding Stress in ALS
Matus, Soledad, Valenzuela, Vicente, Medinas, Danilo B., Hetz, Claudio
Published in International Journal of Cell Biology (2013)
Published in International Journal of Cell Biology (2013)
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Journal Article
The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein
Torres, Mauricio, Medinas, Danilo B., Matamala, José Manuel, Woehlbier, Ute, Cornejo, Víctor Hugo, Solda, Tatiana, Andreu, Catherine, Rozas, Pablo, Matus, Soledad, Muñoz, Natalia, Vergara, Carmen, Cartier, Luis, Soto, Claudio, Molinari, Maurizio, Hetz, Claudio
Published in The Journal of biological chemistry (25.09.2015)
Published in The Journal of biological chemistry (25.09.2015)
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Journal Article
Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis
Bilches Medinas, Danilo, Malik, Sajid, Yıldız‐Bölükbaşı, Esra, Borgonovo, Janina, Saaranen, Mirva J, Urra, Hery, Pulgar, Eduardo, Afzal, Muhammad, Contreras, Darwin, Wright, Madison T, Bodaleo, Felipe, Quiroz, Gabriel, Rozas, Pablo, Mumtaz, Sara, Díaz, Rodrigo, Rozas, Carlos, Cabral‐Miranda, Felipe, Piña, Ricardo, Valenzuela, Vicente, Uyan, Ozgun, Reardon, Christopher, Woehlbier, Ute, Brown, Robert H, Sena‐Esteves, Miguel, Gonzalez‐Billault, Christian, Morales, Bernardo, Plate, Lars, Ruddock, Lloyd W, Concha, Miguel L, Hetz, Claudio, Tolun, Aslıhan
Published in The EMBO journal (17.01.2022)
Published in The EMBO journal (17.01.2022)
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Journal Article