Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression
Eggert, Tobias, Wolter, Katharina, Ji, Juling, Ma, Chi, Yevsa, Tetyana, Klotz, Sabrina, Medina-Echeverz, José, Longerich, Thomas, Forgues, Marshonna, Reisinger, Florian, Heikenwalder, Mathias, Wang, Xin Wei, Zender, Lars, Greten, Tim F.
Published in Cancer cell (10.10.2016)
Published in Cancer cell (10.10.2016)
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Journal Article
Synergistic cancer immunotherapy combines MVA-CD40L induced innate and adaptive immunity with tumor targeting antibodies
Medina-Echeverz, José, Hinterberger, Maria, Testori, Marco, Geiger, Marlene, Giessel, Raphael, Bathke, Barbara, Kassub, Ronny, Gräbnitz, Fabienne, Fiore, Giovanna, Wennier, Sonia T., Chaplin, Paul, Suter, Mark, Hochrein, Hubertus, Lauterbach, Henning
Published in Nature communications (06.11.2019)
Published in Nature communications (06.11.2019)
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Journal Article
CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation
Otano, Itziar, Azpilikueta, Arantza, Glez-Vaz, Javier, Alvarez, Maite, Medina-Echeverz, José, Cortés-Domínguez, Ivan, Ortiz-de-Solorzano, Carlos, Ellmark, Peter, Fritzell, Sara, Hernandez-Hoyos, Gabriela, Nelson, Michelle Hase, Ochoa, María Carmen, Bolaños, Elixabet, Cuculescu, Doina, Jaúregui, Patricia, Sanchez-Gregorio, Sandra, Etxeberria, Iñaki, Rodriguez-Ruiz, María E., Sanmamed, Miguel F., Teijeira, Álvaro, Berraondo, Pedro, Melero, Ignacio
Published in Nature communications (15.12.2021)
Published in Nature communications (15.12.2021)
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Journal Article
Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication
Hinterberger, Maria, Endt, Kathrin, Bathke, Barbara, Habjan, Matthias, Heiseke, Alexander, Schweneker, Marc, Von Rohrscheidt, Julia, Atay, Cigdem, Chaplin, Paul, Kalla, Markus, Hausmann, Jürgen, Schmittwolf, Carolin, Lauterbach, Henning, Volkmann, Ariane, Hochrein, Hubertus, Medina-Echeverz, José
Published in Scientific reports (30.03.2023)
Published in Scientific reports (30.03.2023)
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Journal Article
Synergistic antitumor response with recombinant modified virus Ankara armed with CD40L and CD137L against peritoneal carcinomatosis
Bella, Ángela, Arrizabalaga, Leire, Di Trani, Claudia Augusta, Cirella, Assunta, Fernandez-Sendin, Myriam, Gomar, Celia, Russo-Cabrera, Joan Salvador, Rodríguez, Inmaculada, González-Gomariz, José, Alvarez, Maite, Teijeira, Álvaro, Medina-Echeverz, José, Hinterberger, Maria, Hochrein, Hubertus, Melero, Ignacio, Berraondo, Pedro, Aranda, Fernando
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Journal Article
Anchoring interferon alpha to apolipoprotein A‐I reduces hematological toxicity while enhancing immunostimulatory properties
Fioravanti, Jessica, González, Iranzu, Medina‐Echeverz, José, Larrea, Esther, Ardaiz, Nuria, González‐Aseguinolaza, Gloria, Prieto, Jesús, Berraondo, Pedro
Published in Hepatology (Baltimore, Md.) (01.06.2011)
Published in Hepatology (Baltimore, Md.) (01.06.2011)
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Journal Article
Tumor induced hepatic myeloid derived suppressor cells can cause moderate liver damage
Eggert, Tobias, Medina-Echeverz, José, Kapanadze, Tamar, Kruhlak, Michael J, Korangy, Firouzeh, Greten, Tim F
Published in PloS one (17.11.2014)
Published in PloS one (17.11.2014)
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Journal Article
Systemic Agonistic Anti-CD40 Treatment of Tumor-Bearing Mice Modulates Hepatic Myeloid-Suppressive Cells and Causes Immune-Mediated Liver Damage
Medina-Echeverz, José, Ma, Chi, Duffy, Austin G, Eggert, Tobias, Hawk, Nga, Kleiner, David E, Korangy, Firouzeh, Greten, Tim F
Published in Cancer immunology research (01.05.2015)
Published in Cancer immunology research (01.05.2015)
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Journal Article
Tumor‐induced CD11b+ Gr‐1+ myeloid‐derived suppressor cells exacerbate immune‐mediated hepatitis in mice in a CD40‐dependent manner
Kapanadze, Tamar, Medina‐Echeverz, José, Gamrekelashvili, Jaba, Weiss, Jonathan M., Wiltrout, Robert H., Kapoor, Veena, Hawk, Nga, Terabe, Masaki, Berzofsky, Jay A., Manns, Michael P., Wang, Ena, Marincola, Francesco M., Korangy, Firouzeh, Greten, Tim F.
Published in European journal of immunology (01.04.2015)
Published in European journal of immunology (01.04.2015)
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Journal Article
Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases
Medina-Echeverz, José, Fioravanti, Jessica, Díaz-Valdés, Nancy, Frank, Kathrin, Aranda, Fernando, Gomar, Celia, Ardaiz, Nuria, Dotor, Javier, Umansky, Viktor, Prieto, Jesús, Berraondo, Pedro
Published in PloS one (05.05.2014)
Published in PloS one (05.05.2014)
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Journal Article
The yin and yang of evasion and immune activation in HCC
Makarova-Rusher, Oxana V, Medina-Echeverz, José, Duffy, Austin G, Greten, Tim F
Published in Journal of hepatology (01.06.2015)
Published in Journal of hepatology (01.06.2015)
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Journal Article
NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis
Ma, Chi, Kesarwala, Aparna H., Eggert, Tobias, Medina-Echeverz, José, Kleiner, David E., Jin, Ping, Stroncek, David F., Terabe, Masaki, Kapoor, Veena, ElGindi, Mei, Han, Miaojun, Thornton, Angela M., Zhang, Haibo, Egger, Michèle, Luo, Ji, Felsher, Dean W., McVicar, Daniel W., Weber, Achim, Heikenwalder, Mathias, Greten, Tim F.
Published in Nature (London) (10.03.2016)
Published in Nature (London) (10.03.2016)
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Journal Article
Characterization of woodchuck apolipoprotein A-I: A new tool for drug delivery and identification of altered isoforms in the woodchuck chronic hepatitis model
Fioravanti, Jessica, Gomar, Celia, Medina-Echeverz, José, Otano, Itziar, Benito, Alberto, Prieto, Jesús, González-Aseguinolaza, Gloria, Berraondo, Pedro
Published in Journal of medical virology (01.07.2011)
Published in Journal of medical virology (01.07.2011)
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Journal Article
Hepatic myeloid-derived suppressor cells in cancer
Medina-Echeverz, José, Eggert, Tobias, Han, Miaojun, Greten, Tim F.
Published in Cancer Immunology, Immunotherapy (01.08.2015)
Published in Cancer Immunology, Immunotherapy (01.08.2015)
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Journal Article
Successful colon cancer eradication after chemoimmunotherapy is associated with profound phenotypic change of intratumoral myeloid cells
Medina-Echeverz, José, Fioravanti, Jessica, Zabala, Maider, Ardaiz, Nuria, Prieto, Jesús, Berraondo, Pedro
Published in The Journal of immunology (1950) (15.01.2011)
Published in The Journal of immunology (1950) (15.01.2011)
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Journal Article
Mouse Models of Peritoneal Carcinomatosis to Develop Clinical Applications
Bella, Ángela, Di Trani, Claudia Augusta, Fernández-Sendin, Myriam, Arrizabalaga, Leire, Cirella, Assunta, Teijeira, Álvaro, Medina-Echeverz, José, Melero, Ignacio, Berraondo, Pedro, Aranda, Fernando
Published in Cancers (25.02.2021)
Published in Cancers (25.02.2021)
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Journal Article
Overexpression of apolipoprotein A-I fused to an anti-transforming growth factor beta peptide modulates the tumorigenicity and immunogenicity of mouse colon cancer cells
Medina-Echeverz, José, Vasquez, Marcos, Gomar, Celia, Ardaiz, Nuria, Berraondo, Pedro
Published in Cancer Immunology, Immunotherapy (01.06.2015)
Published in Cancer Immunology, Immunotherapy (01.06.2015)
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Journal Article
Intravenous immunoglobulin promotes antitumor responses by modulating macrophage polarization
Domínguez-Soto, Angeles, de las Casas-Engel, Mateo, Bragado, Rafael, Medina-Echeverz, José, Aragoneses-Fenoll, Laura, Martín-Gayo, Enrique, van Rooijen, Nico, Berraondo, Pedro, Toribio, María L, Moro, María A, Cuartero, Isabel, Castrillo, Antonio, Sancho, David, Sánchez-Torres, Carmen, Bruhns, Pierre, Sánchez-Ramón, Silvia, Corbí, Angel L
Published in The Journal of immunology (1950) (15.11.2014)
Published in The Journal of immunology (1950) (15.11.2014)
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Journal Article
EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models
Venugopalan, Abhilash, Lee, Min-Jung, Niu, Gang, Medina-Echeverz, José, Tomita, Yusuke, Lizak, Martin J, Cultraro, Constance M, Simpson, Robert Mark, Chen, Xiaoyuan, Trepel, Jane B, Guha, Udayan
Published in Oncotarget (23.08.2016)
Published in Oncotarget (23.08.2016)
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