Correlation of Inhibitory Effects of Polymers on Indomethacin Precipitation in Solution and Amorphous Solid Crystallization Based on Molecular Interaction
Chauhan, Harsh, Kuldipkumar, Anuj, Barder, Timothy, Medek, Ales, Gu, Chong-Hui, Atef, Eman
Published in Pharmaceutical research (01.02.2014)
Published in Pharmaceutical research (01.02.2014)
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Journal Article
Solution Structure of the Antiapoptotic Protein bcl-2
Petros, Andrew M., Medek, Ales, Nettesheim, David G., Kim, Daniel H., Yoon, Ho Sup, Swift, Kerry, Matayoshi, Edmund D., Oltersdorf, Tilman, Fesik, Stephen W.
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2001)
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Journal Article
Central Transition Nuclear Magnetic Resonance in the Presence of Large Quadrupole Couplings: Cobalt-59 Nuclear Magnetic Resonance of Cobaltophthalocyanines
Medek, Ales, Frydman, Veronica, Frydman, Lucio
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (24.06.1999)
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (24.06.1999)
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Journal Article
An approach for high-throughput structure determination of proteins by NMR spectroscopy
Medek, A, Olejniczak, E T, Meadows, R P, Fesik, S W
Published in Journal of biomolecular NMR (01.11.2000)
Published in Journal of biomolecular NMR (01.11.2000)
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Journal Article
Investigation of Polymer/Surfactant Interactions and Their Impact on Itraconazole Solubility and Precipitation Kinetics for Developing Spray-Dried Amorphous Solid Dispersions
Deshpande, Tanvi M, Shi, Helen, Pietryka, John, Hoag, Stephen W, Medek, Ales
Published in Molecular pharmaceutics (05.03.2018)
Published in Molecular pharmaceutics (05.03.2018)
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Journal Article
Overcoming the Bile Salt-Mediated Formation of Nanocolloids That Inhibit Oral Absorption of VX-985
Song, Bin, Bransford, Philip, Peresypkin, Andrey, Medek, Ales, Mudunuri, Praveen, Randles, Edward G., Dworakowski, Wojciech, Kumar, Santosh, Snyder, Phillip W.
Published in Journal of pharmaceutical sciences (01.02.2019)
Published in Journal of pharmaceutical sciences (01.02.2019)
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Journal Article
Solid and liquid phase 59Co NMR studies of cobalamins and their derivatives
Medek, A, Frydman, V, Frydman, L
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.1997)
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Published in Proceedings of the National Academy of Sciences - PNAS (23.12.1997)
Journal Article
APOL1 억제제의 고형분 형태 및 이의 사용 방법
SHRESTHA MUNA, WITKOS FAITH, GAGNON KEVIN JAMES, LI JICONG, SHI YI, MEDEK ALES, MINCHOM JACK RAPHAEL
Year of Publication 20.02.2023
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Year of Publication 20.02.2023
Patent
Milling-Induced Disorder of Pharmaceuticals: One-Phase or Two-Phase System?
Luisi, Brian S., Medek, Ales, Liu, Zhouyuan, Mudunuri, Praveen, Moulton, Brian
Published in Journal of pharmaceutical sciences (01.04.2012)
Published in Journal of pharmaceutical sciences (01.04.2012)
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Journal Article
APOL1 억제제로서의 4-페닐-2-(1H-1,2,3-트리아졸-4-일)피페리딘-4-올 유도체 및 이를 사용하는 방법
GARCIA BARRANTES PEDRO M, SENTER TIMOTHY J, SHIMIZU AKIRA J, DAKIN LESLIE A, BRODNEY MICHAEL A, DOLGIKH ELENA, STONE STEVEN D, MEDEK ALES, TSAY CHARLENE, OLSEN JESSICA H, DANIEL KEVIN B
Year of Publication 30.08.2024
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Year of Publication 30.08.2024
Patent
스피로트리시클릭 APOL1 억제제의 고형분 형태 및 이의 사용 방법
MAGUIRE COURTNEY K, GAGNON KEVIN JAMES, TEESDALE JUSTIN, SHI YI, FERRIS LORI ANN, MEDEK ALES, PERESYPKIN ANDREY, DANIEL KEVIN BRETT, LAI MEI HSIU, JUDELSON MICHAEL DAVID, LAWS STEPHEN W, TSAY CHARLENE, ROSE PETER JAMISON
Year of Publication 22.04.2024
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Year of Publication 22.04.2024
Patent
Chemical Stability of Amorphous Materials: Specific and General Media Effects in the Role of Water in the Degradation of Freeze-Dried Zoniporide
Luthra, Suman A., Shalaev, Evgenyi Y., Medek, Ales, Hong, Jinyang, Pikal, Michael J.
Published in Journal of pharmaceutical sciences (01.09.2012)
Published in Journal of pharmaceutical sciences (01.09.2012)
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Journal Article
4--6-(테트라하이드로-2H-피란-4-일)-1,5-디하이드로피롤로[2,3-f]인다졸-7-일)벤조산의 고형분 형태
SHI YI, TORRICO GUZMAN ELISA A, SAWANT RUPA, LIU SIYING, MEDEK ALES, RODAY SETU, LAI MEI HSIU, OVERHOFF KIRK ALAN, SPOSATO MARISA, HU KAN NIAN, SOKOLOWSKY KATHLEEN PAIGE, SONG ZHENGTIAN, GIROUX SIMON
Year of Publication 21.07.2023
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Year of Publication 21.07.2023
Patent
The potency–insolubility conundrum in pharmaceuticals: Mechanism and solution for hepatitis C protease inhibitors
Connelly, Patrick R., Snyder, Phillip W., Zhang, Yuegang, McClain, Brian, Quinn, Brian P., Johnston, Steve, Medek, Ales, Tanoury, Jerry, Griffith, James, Patrick Walters, W., Dokou, Eleni, Knezic, Dragutin, Bransford, Philip
Published in Biophysical chemistry (01.01.2015)
Published in Biophysical chemistry (01.01.2015)
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CFTR 조절제의 결정질 형태
HADIDA RUAH SARA SABINA, ZHOU JINGLAN, LI JICONG, PIERRE FABRICE, MCCARTNEY JASON, SHI YI, PARASELLI PRASUNA, MEDEK ALES, CLEVELAND THOMAS, GAGNON KEVIN J, SHRESTHA MUNA, ZHANG BEILI, SWIFT SARA E, LU JENNIFER, MILLER MARK THOMAS, GROOTENHUIS PETER, ANDERSON COREY DON, FRIEMAN BRYAN, WALDO MICHAEL, COON TIMOTHY RICHARD, ZWICKER CARL L, CLEMENS JEREMY J
Year of Publication 18.05.2022
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Year of Publication 18.05.2022
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