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microRNA-496 – A new, potentially aging-relevant regulator of mTOR
Rubie, Claudia, Kölsch, Kathrin, Halajda, Beata, Eichler, Hermann, Wagenpfeil, Stefan, Roemer, Klaus, Glanemann, Matthias
Published in Cell cycle (Georgetown, Tex.) (01.01.2016)
Published in Cell cycle (Georgetown, Tex.) (01.01.2016)
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Takeda G Protein-Coupled Receptor 5-Mechanistic Target of Rapamycin Complex 1 Signaling Contributes to the Increment of Glucagon-Like Peptide-1 Production after Roux-en-Y Gastric Bypass
Zhai, Hening, Li, Zhi, Peng, Miao, Huang, Zhaoqi, Qin, Tingfeng, Chen, Linxi, Li, Hanbing, Zhang, Heng, Zhang, Weizhen, Xu, Geyang
Published in EBioMedicine (01.06.2018)
Published in EBioMedicine (01.06.2018)
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Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition
Kasner, Margaret T., Mick, Rosemarie, Jeschke, Grace R., Carabasi, Matthew, Filicko-O’Hara, Joanne, Flomenberg, Neal, Frey, Noelle V., Hexner, Elizabeth O., Luger, Selina M., Loren, Alison W., Mangan, James K., Wagner, John L., Weiss, Mark, Carroll, Martin, Perl, Alexander E.
Published in Investigational new drugs (01.08.2018)
Published in Investigational new drugs (01.08.2018)
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The signaling pathways underlying starvation-induced upregulation of α-mannosidase Ams1 in Saccharomyces cerevisiae
Umekawa, Midori, Ujihara, Masato, Makishima, Kazuki, Yamamoto, Shohei, Takematsu, Hiromu, Wakayama, Mamoru
Published in Biochimica et biophysica acta (01.06.2016)
Published in Biochimica et biophysica acta (01.06.2016)
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Intake of branched-chain or essential amino acids attenuates the elevation in muscle levels of PGC-1α4 mRNA caused by resistance exercise
Samuelsson, Hedvig, Moberg, Marcus, Apró, William, Ekblom, Björn, Blomstrand, Eva
Published in American journal of physiology: endocrinology and metabolism (01.07.2016)
Published in American journal of physiology: endocrinology and metabolism (01.07.2016)
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Resistance exercise, but not endurance exercise, induces IKKβ phosphorylation in human skeletal muscle of training-accustomed individuals
Møller, Andreas Buch, Vendelbo, Mikkel Holm, Rahbek, Stine Klejs, Clasen, Berthil Forrest, Schjerling, Peter, Vissing, Kristian, Jessen, Niels
Published in Pflügers Archiv (01.12.2013)
Published in Pflügers Archiv (01.12.2013)
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Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle
Dickinson, Jared M., Drummond, Micah J., Fry, Christopher S., Gundermann, David M., Walker, Dillon K., Timmerman, Kyle L., Volpi, Elena, Rasmussen, Blake B.
Published in Metabolism, clinical and experimental (01.01.2013)
Published in Metabolism, clinical and experimental (01.01.2013)
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The Importance of Autophagy in Cardioprotection
Sciarretta, Sebastiano, Yee, Derek, Shenoy, Varun, Nagarajan, Narayani, Sadoshima, Junichi
Published in High blood pressure & cardiovascular prevention (01.03.2014)
Published in High blood pressure & cardiovascular prevention (01.03.2014)
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Phase I study of orally administered 14 Carbon-isotope labelled-vistusertib (AZD2014), a dual TORC1/2 kinase inhibitor, to assess the absorption, metabolism, excretion, and pharmacokinetics in patients with advanced solid malignancies
MacDonald, Alexander, Scarfe, Graeme, Magirr, Dominic, Sarvotham, Tinnu, Charlton, Julie, Brugger, Wolfram, Dean, Emma
Published in Cancer chemotherapy and pharmacology (01.04.2019)
Published in Cancer chemotherapy and pharmacology (01.04.2019)
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Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
Koh, Ara, Molinaro, Antonio, Ståhlman, Marcus, Khan, Muhammad Tanweer, Schmidt, Caroline, Mannerås-Holm, Louise, Wu, Hao, Carreras, Alba, Jeong, Heeyoon, Olofsson, Louise E., Bergh, Per-Olof, Gerdes, Victor, Hartstra, Annick, de Brauw, Maurits, Perkins, Rosie, Nieuwdorp, Max, Bergström, Göran, Bäckhed, Fredrik
Published in Cell (01.11.2018)
Published in Cell (01.11.2018)
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Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease
Dorjbal, Batsukh, Stinson, Jeffrey R., Ma, Chi A., Weinreich, Michael A., Miraghazadeh, Bahar, Hartberger, Julia M., Frey-Jakobs, Stefanie, Weidinger, Stephan, Moebus, Lena, Franke, Andre, Schäffer, Alejandro A., Bulashevska, Alla, Fuchs, Sebastian, Ehl, Stephan, Limaye, Sandhya, Arkwright, Peter D., Briggs, Tracy A., Langley, Claire, Bethune, Claire, Whyte, Andrew F., Alachkar, Hana, Nejentsev, Sergey, DiMaggio, Thomas, Nelson, Celeste G., Stone, Kelly D., Nason, Martha, Brittain, Erica H., Oler, Andrew J., Veltri, Daniel P., Leahy, T. Ronan, Conlon, Niall, Poli, Maria C., Borzutzky, Arturo, Cohen, Jeffrey I., Davis, Joie, Lambert, Michele P., Romberg, Neil, Sullivan, Kathleen E., Paris, Kenneth, Freeman, Alexandra F., Lucas, Laura, Chandrakasan, Shanmuganathan, Savic, Sinisa, Hambleton, Sophie, Patel, Smita Y., Jordan, Michael B., Theos, Amy, Lebensburger, Jeffrey, Atkinson, T. Prescott, Torgerson, Troy R., Chinn, Ivan K., Milner, Joshua D., Grimbacher, Bodo, Cook, Matthew C., Snow, Andrew L.
Published in Journal of allergy and clinical immunology (01.04.2019)
Published in Journal of allergy and clinical immunology (01.04.2019)
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Dietary protein, exercise, ageing and physical inactivity: interactive influences on skeletal muscle proteostasis
Deane, Colleen S., Ely, Isabel A., Wilkinson, Daniel J., Smith, Kenneth, Phillips, Bethan E., Atherton, Philip J.
Published in Proceedings of the Nutrition Society (01.05.2021)
Published in Proceedings of the Nutrition Society (01.05.2021)
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Muscle Protein Anabolic Resistance to Essential Amino Acids Does Not Occur in Healthy Older Adults Before or After Resistance Exercise Training
Moro, Tatiana, Brightwell, Camille R, Deer, Rachel R, Graber, Ted G, Galvan, Elfego, Fry, Christopher S, Volpi, Elena, Rasmussen, Blake B
Published in The Journal of nutrition (01.06.2018)
Published in The Journal of nutrition (01.06.2018)
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Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
Tebay, Lauren E., Robertson, Holly, Durant, Stephen T., Vitale, Steven R., Penning, Trevor M., Dinkova-Kostova, Albena T., Hayes, John D.
Published in Free radical biology & medicine (01.11.2015)
Published in Free radical biology & medicine (01.11.2015)
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Persistently Elevated mTOR Complex 1-S6 Kinase 1 Disrupts DARPP-32–Dependent D1 Dopamine Receptor Signaling and Behaviors
Lin, Raozhou, Learman, Lisa N., Na, Chan-Hyun, Renuse, Santosh, Chen, Kevin T., Chen, Po Yu, Lee, Gum-Hwa, Xiao, Bo, Resnick, Susan M., Troncoso, Juan C., Szumlinski, Karen K., Linden, David J., Park, Joo-Min, Savonenko, Alena, Pandey, Akhilesh, Worley, Paul F.
Published in Biological psychiatry (1969) (01.06.2021)
Published in Biological psychiatry (1969) (01.06.2021)
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