A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke
Chappie, Joshua S., Mears, Jason A., Fang, Shunming, Leonard, Marilyn, Schmid, Sandra L., Milligan, Ronald A., Hinshaw, Jenny E., Dyda, Fred
Published in Cell (30.09.2011)
Published in Cell (30.09.2011)
Get full text
Journal Article
Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission
Stepanyants, Natalia, Macdonald, Patrick J, Francy, Christopher A, Mears, Jason A, Qi, Xin, Ramachandran, Rajesh
Published in Molecular biology of the cell (01.09.2015)
Published in Molecular biology of the cell (01.09.2015)
Get full text
Journal Article
A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission
Macdonald, Patrick J, Stepanyants, Natalia, Mehrotra, Niharika, Mears, Jason A, Qi, Xin, Sesaki, Hiromi, Ramachandran, Rajesh
Published in Molecular biology of the cell (15.06.2014)
Published in Molecular biology of the cell (15.06.2014)
Get full text
Journal Article
The Mechanoenzymatic Core of Dynamin-related Protein 1 Comprises the Minimal Machinery Required for Membrane Constriction
Francy, Christopher A., Alvarez, Frances J.D., Zhou, Louie, Ramachandran, Rajesh, Mears, Jason A.
Published in The Journal of biological chemistry (01.05.2015)
Published in The Journal of biological chemistry (01.05.2015)
Get full text
Journal Article
Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity
Macdonald, Patrick J., Francy, Christopher A., Stepanyants, Natalia, Lehman, Lance, Baglio, Anthony, Mears, Jason A., Qi, Xin, Ramachandran, Rajesh
Published in The Journal of biological chemistry (01.01.2016)
Published in The Journal of biological chemistry (01.01.2016)
Get full text
Journal Article
Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass
Akinbiyi, Elizabeth O., Abramowitz, Lara K., Bauer, Brianna L., Stoll, Maria S. K., Hoppel, Charles L., Hsiao, Chao-Pin, Hanover, John A., Mears, Jason A.
Published in Scientific reports (11.11.2021)
Published in Scientific reports (11.11.2021)
Get full text
Journal Article
Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif
Pérez-Jover, Isabel, Rochon, Kristy, Hu, Di, Mahajan, Mukesh, Madan Mohan, Pooja, Santos-Pérez, Isaac, Ormaetxea Gisasola, Julene, Martinez Galvez, Juan Manuel, Agirre, Jon, Qi, Xin, Mears, Jason A., Shnyrova, Anna V., Ramachandran, Rajesh
Published in Nature communications (02.01.2024)
Published in Nature communications (02.01.2024)
Get full text
Journal Article
Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues
Schulz, Timothy A, Choi, Mal-Gi, Raychaudhuri, Sumana, Mears, Jason A, Ghirlando, Rodolfo, Hinshaw, Jenny E, Prinz, William A
Published in The Journal of cell biology (14.12.2009)
Published in The Journal of cell biology (14.12.2009)
Get full text
Journal Article
Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1
Rochon, Kristy, Bauer, Brianna L., Roethler, Nathaniel A., Buckley, Yuli, Su, Chih-Chia, Huang, Wei, Ramachandran, Rajesh, Stoll, Maria S. K., Yu, Edward W., Taylor, Derek J., Mears, Jason A.
Published in Nature communications (13.02.2024)
Published in Nature communications (13.02.2024)
Get full text
Journal Article
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity
Watson, Dionysios C, Bayik, Defne, Storevik, Simon, Moreino, Shannon Sherwin, Sprowls, Samuel A, Han, Jianhua, Augustsson, Mina Thue, Lauko, Adam, Sravya, Palavalasa, Røsland, Gro Vatne, Troike, Katie, Tronstad, Karl Johan, Wang, Sabrina, Sarnow, Katharina, Kay, Kristen, Lunavat, Taral R, Silver, Daniel J, Dayal, Sahil, Joseph, Justin Vareecal, Mulkearns-Hubert, Erin, Ystaas, Lars Andreas Rømo, Deshpande, Gauravi, Guyon, Joris, Zhou, Yadi, Magaut, Capucine R, Seder, Juliana, Neises, Laura, Williford, Sarah E, Meiser, Johannes, Scott, Andrew J, Sajjakulnukit, Peter, Mears, Jason A, Bjerkvig, Rolf, Chakraborty, Abhishek, Daubon, Thomas, Cheng, Feixiong, Lyssiotis, Costas A, Wahl, Daniel R, Hjelmeland, Anita B, Hossain, Jubayer A, Miletic, Hrvoje, Lathia, Justin D
Published in Nature cancer (01.05.2023)
Published in Nature cancer (01.05.2023)
Get more information
Journal Article
Mitochondrial Dysfunction in Primary Ovarian Insufficiency
Tiosano, Dov, Mears, Jason A, Buchner, David A
Published in Endocrinology (Philadelphia) (01.10.2019)
Published in Endocrinology (Philadelphia) (01.10.2019)
Get full text
Journal Article
Cryo-EM Studies of Drp1 Reveal Cardiolipin Interactions that Activate the Helical Oligomer
Francy, Christopher A., Clinton, Ryan W., Fröhlich, Chris, Murphy, Colleen, Mears, Jason A.
Published in Scientific reports (06.09.2017)
Published in Scientific reports (06.09.2017)
Get full text
Journal Article
Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor
Clinton, Ryan W., Francy, Christopher A., Ramachandran, Rajesh, Qi, Xin, Mears, Jason A.
Published in The Journal of biological chemistry (01.01.2016)
Published in The Journal of biological chemistry (01.01.2016)
Get full text
Journal Article
Solvent accessibility of E1α and E1β residues with known missense mutations causing pyruvate dehydrogenase complex (PDC) deficiency: Impact on PDC‐E1 structure and function
Ducich, Nicole H., Mears, Jason A., Bedoyan, Jirair K.
Published in Journal of inherited metabolic disease (01.05.2022)
Published in Journal of inherited metabolic disease (01.05.2022)
Get full text
Journal Article