Phase II study of single-agent panitumumab in patients with incurable cutaneous squamous cell carcinoma
Foote, M.C., McGrath, M., Guminski, A., Hughes, B.G.M., Meakin, J., Thomson, D., Zarate, D., Simpson, F., Porceddu, S.V.
Published in Annals of oncology (01.10.2014)
Published in Annals of oncology (01.10.2014)
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Journal Article
The beta secretase BACE1 regulates the expression of insulin receptor in the liver
Meakin, Paul J, Mezzapesa, Anna, Benabou, Eva, Haas, Mary E, Bonardo, Bernadette, Grino, Michel, Brunel, Jean-Michel, Desbois-Mouthon, Christèle, Biddinger, Sudha B, Govers, Roland, Ashford, Michael L J, Peiretti, Franck
Published in Nature communications (03.04.2018)
Published in Nature communications (03.04.2018)
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Journal Article
Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis
Chowdhry, Sudhir, Nazmy, Maiiada H., Meakin, Paul J., Dinkova-Kostova, Albena T., Walsh, Shaun V., Tsujita, Tadayuki, Dillon, John F., Ashford, Michael L.J., Hayes, John D.
Published in Free radical biology & medicine (15.01.2010)
Published in Free radical biology & medicine (15.01.2010)
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Journal Article
Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation
McGuire, Victoria A, Ruiz-Zorrilla Diez, Tamara, Emmerich, Christoph H, Strickson, Sam, Ritorto, Maria Stella, Sutavani, Ruhcha V, Weiβ, Anne, Houslay, Kirsty F, Knebel, Axel, Meakin, Paul J, Phair, Iain R, Ashford, Michael L J, Trost, Matthias, Arthur, J Simon C
Published in Scientific reports (08.08.2016)
Published in Scientific reports (08.08.2016)
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Journal Article
The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesis
Deldicque, Louise, Cani, Patrice D, Philp, Andrew, Raymackers, Jean-Marc, Meakin, Paul J, Ashford, Michael L J, Delzenne, Nathalie M, Francaux, Marc, Baar, Keith
Published in American journal of physiology: endocrinology and metabolism (01.11.2010)
Published in American journal of physiology: endocrinology and metabolism (01.11.2010)
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Journal Article
DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks
Pinto, Lia M, Pailas, Alexandros, Bondarchenko, Max, Sharma, Abhishek Bharadwaj, Neumann, Katrin, Rizzo, Anthony J, Jeanty, Céline, Nicot, Nathalie, Racca, Carine, Graham, Mindy K, Naughton, Catherine, Liu, Yaqun, Chen, Chun-Long, Meakin, Paul J, Gilbert, Nick, Britton, Sébastien, Meeker, Alan K, Heaphy, Christopher M, Larminat, Florence, Van Dyck, Eric
Published in Nucleic acids research (09.02.2024)
Published in Nucleic acids research (09.02.2024)
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Journal Article
Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice
Meakin, Paul J, Harper, Alex J, Hamilton, D Lee, Gallagher, Jennifer, McNeilly, Alison D, Burgess, Laura A, Vaanholt, Lobke M, Bannon, Kirsten A, Latcham, Judy, Hussain, Ishrut, Speakman, John R, Howlett, David R, Ashford, Michael L J
Published in Biochemical journal (01.01.2012)
Published in Biochemical journal (01.01.2012)
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Journal Article
PTPRD and DCC Are Novel BACE1 Substrates Differentially Expressed in Alzheimer's Disease: A Data Mining and Bioinformatics Study
Taylor, Hannah A, Simmons, Katie J, Clavane, Eva M, Trevelyan, Christopher J, Brown, Jane M, Przemyłska, Lena, Watt, Nicole T, Matthews, Laura C, Meakin, Paul J
Published in International journal of molecular sciences (20.04.2022)
Published in International journal of molecular sciences (20.04.2022)
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Journal Article
Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress
Al-Mubarak, Bashayer R., Bell, Karen F.S., Chowdhry, Sudhir, Meakin, Paul J., Baxter, Paul S., McKay, Sean, Dando, Owen, Ashford, Michael L.J., Gazaryan, Irina, Hayes, John D., Hardingham, Giles E.
Published in Redox biology (01.11.2021)
Published in Redox biology (01.11.2021)
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Journal Article
Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice
Meakin, Paul J, Jalicy, Susan M, Montagut, Gemma, Allsop, David J P, Cavellini, Daniella L, Irvine, Stuart W, McGinley, Christopher, Liddell, Mary K, McNeilly, Alison D, Parmionova, Karolina, Liu, Yu-Ru, Bailey, Charlotte L S, Dale, J Kim, Heisler, Lora K, McCrimmon, Rory J, Ashford, Michael L J
Published in Scientific reports (08.01.2018)
Published in Scientific reports (08.01.2018)
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Journal Article
Micro-mechanical damage of needle puncture on bovine annulus fibrosus fibrils studied using polarization-resolved Second Harmonic Generation(P-SHG) microscopy
Wang, J.-Y., Mansfield, J.C., Brasselet, S., Vergari, C., Meakin, J.R., Winlove, C.P.
Published in Journal of the mechanical behavior of biomedical materials (01.06.2021)
Published in Journal of the mechanical behavior of biomedical materials (01.06.2021)
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Journal Article
Nrf2 target genes can be controlled by neuronal activity in the absence of Nrf2 and astrocytes
Deighton, Ruth F, Márkus, Nóra M, Al-Mubarak, Bashayer, Bell, Karen F S, Papadia, Sofia, Meakin, Paul J, Chowdhry, Sudhir, Hayes, John D, Hardingham, Giles E
Published in Proceedings of the National Academy of Sciences - PNAS (06.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (06.05.2014)
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Journal Article
Computer-aided detection in musculoskeletal projection radiography: A systematic review
Gundry, M., Knapp, K., Meertens, R., Meakin, J.R.
Published in Radiography (London, England. 1995) (01.05.2018)
Published in Radiography (London, England. 1995) (01.05.2018)
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Journal Article
Sex Differences in the Associations between L-Arginine Pathway Metabolites, Skeletal Muscle Mass and Function, and their Responses to Resistance Exercise, in Old Age
da Boit, M., Tommasi, S., Elliot, D., Zinellu, A., Sotgia, S., Sibson, R., Meakin, J. R., Aspden, R. M., Carru, C., Mangoni, A. A., Gray, Stuart R.
Published in The Journal of nutrition, health & aging (01.04.2018)
Published in The Journal of nutrition, health & aging (01.04.2018)
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Journal Article
3-D laser confocal microscopy study of the oxidation of NdFeB magnets in atmospheric conditions
Meakin, J.P., Speight, J.D., Sheridan, R.S., Bradshaw, A., Harris, I.R., Williams, A.J., Walton, A.
Published in Applied surface science (15.08.2016)
Published in Applied surface science (15.08.2016)
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Journal Article
Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation
Meakin, Paul J, Morrison, Vicky L, Sneddon, Claire C, Savinko, Terhi, Uotila, Liisa, Jalicy, Susan M, Gabriel, Jennie L, Kang, Li, Ashford, Michael L J, Fagerholm, Susanna C
Published in PloS one (25.09.2015)
Published in PloS one (25.09.2015)
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Journal Article