Erythroferrone inhibits the induction of hepcidin by BMP6
Arezes, João, Foy, Niall, McHugh, Kirsty, Sawant, Anagha, Quinkert, Doris, Terraube, Virginie, Brinth, Alette, Tam, May, LaVallie, Edward R., Taylor, Stephen, Armitage, Andrew E., Pasricha, Sant-Rayn, Cunningham, Orla, Lambert, Matthew, Draper, Simon J., Jasuja, Reema, Drakesmith, Hal
Published in Blood (04.10.2018)
Published in Blood (04.10.2018)
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Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA–B27
Chen, Liye, Fischer, Roman, Peng, Yanchun, Reeves, Emma, McHugh, Kirsty, Ternette, Nicola, Hanke, Tomas, Dong, Tao, Elliott, Tim, Shastri, Nilabh, Kollnberger, Simon, James, Edward, Kessler, Benedikt, Bowness, Paul
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2014)
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Hepcidin is regulated by promoter-associated histone acetylation and HDAC3
Pasricha, Sant-Rayn, Lim, Pei Jin, Duarte, Tiago L., Casu, Carla, Oosterhuis, Dorenda, Mleczko-Sanecka, Katarzyna, Suciu, Maria, Da Silva, Ana Rita, Al-Hourani, Kinda, Arezes, João, McHugh, Kirsty, Gooding, Sarah, Frost, Joe N., Wray, Katherine, Santos, Ana, Porto, Graça, Repapi, Emmanouela, Gray, Nicki, Draper, Simon J., Ashley, Neil, Soilleux, Elizabeth, Olinga, Peter, Muckenthaler, Martina U., Hughes, Jim R., Rivella, Stefano, Milne, Thomas A., Armitage, Andrew E., Drakesmith, Hal
Published in Nature communications (01.09.2017)
Published in Nature communications (01.09.2017)
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Journal Article
Human Basigin (CD147) Does Not Directly Interact with SARS-CoV-2 Spike Glycoprotein
Ragotte, Robert J, Pulido, David, Donnellan, Francesca R, Hill, Michelle L, Gorini, Giacomo, Davies, Hannah, Brun, Juliane, McHugh, Kirsty, King, Lloyd D W, Skinner, Katherine, Miura, Kazutoyo, Long, Carole A, Zitzmann, Nicole, Draper, Simon J
Published in mSphere (25.08.2021)
Published in mSphere (25.08.2021)
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Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens
Barrett, Jordan R, Silk, Sarah E, Mkindi, Catherine G, Kwiatkowska, Karolina M, Hou, Mimi M, Lias, Amelia M, Kalinga, Wilmina F, Mtaka, Ivanny M, McHugh, Kirsty, Bardelli, Martino, Davies, Hannah, King, Lloyd D W, Edwards, Nick J, Chauhan, Virander S, Mukherjee, Paushali, Rwezaula, Stella, Chitnis, Chetan E, Olotu, Ally I, Minassian, Angela M, Draper, Simon J, Nielsen, Carolyn M
Published in Frontiers in immunology (17.01.2024)
Published in Frontiers in immunology (17.01.2024)
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Intrinsic Folding Properties of the HLA-B27 Heavy Chain Revealed by Single Chain Trimer Versions of Peptide-Loaded Class I Major Histocompatibility Complex Molecules
Lenart, Izabela, Truong, Linh-Huyen, Nguyen, Dinh Dung, Rasiukienė, Olga, Tsao, Edward, Armstrong, Jonathan, Kumar, Pankaj, McHugh, Kirsty, Pereira, Branca I., Maan, Balraj S., Garstka, Malgorzata A., Bowness, Paul, Blake, Neil, Powis, Simon J., Gould, Keith, Nesbeth, Darren, Antoniou, Antony N.
Published in Frontiers in immunology (25.07.2022)
Published in Frontiers in immunology (25.07.2022)
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Journal Article
Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondylarthritis
Payeli, Sravan K., Kollnberger, Simon, Marroquin Belaunzaran, Osiris, Thiel, Markus, McHugh, Kirsty, Giles, Joanna, Shaw, Jacqueline, Kleber, Sascha, Ridley, Anna, Wong-Baeza, Isabel, Keidel, Sarah, Kuroki, Kimiko, Maenaka, Katsumi, Wadle, Andreas, Renner, Christoph, Bowness, Paul
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2012)
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Journal Article
HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I
Giles, Joanna, Shaw, Jackie, Piper, Christopher, Wong-Baeza, Isabel, McHugh, Kirsty, Ridley, Anna, Li, Demin, Lenart, Izabela, Antoniou, Antony N, DiGleria, Katilin, Kuroki, Kimiko, Maenaka, Katsumi, Bowness, Paul, Kollnberger, Simon
Published in The Journal of immunology (1950) (15.06.2012)
Published in The Journal of immunology (1950) (15.06.2012)
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Journal Article
Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply
McHugh, Kirsty, Rysnik, Oliwia, Kollnberger, Simon, Shaw, Jacqueline, Utriainen, Lotta, Al-Mossawi, Mohammad Hussein, Payeli, Sravan, Marroquin, Osiris, Milling, Simon, Renner, Christoph, Bowness, Paul
Published in Annals of the rheumatic diseases (01.04.2014)
Published in Annals of the rheumatic diseases (01.04.2014)
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Journal Article
Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly
Minassian, Angela M, Themistocleous, Yrene, Silk, Sarah E, Barrett, Jordan R, Kemp, Alison, Quinkert, Doris, Nielsen, Carolyn M, Edwards, Nick J, Rawlinson, Thomas A, Ramos Lopez, Fernando, Roobsoong, Wanlapa, Ellis, Katherine Jd, Cho, Jee-Sun, Aunin, Eerik, Otto, Thomas D, Reid, Adam J, Bach, Florian A, Labbé, Geneviève Mc, Poulton, Ian D, Marini, Arianna, Zaric, Marija, Mulatier, Margaux, Lopez Ramon, Raquel, Baker, Megan, Mitton, Celia H, Sousa, Jason C, Rachaphaew, Nattawan, Kumpitak, Chalermpon, Maneechai, Nongnuj, Suansomjit, Chayanut, Piteekan, Tianrat, Hou, Mimi M, Khozoee, Baktash, McHugh, Kirsty, Roberts, David J, Lawrie, Alison M, Blagborough, Andrew M, Nugent, Fay L, Taylor, Iona J, Johnson, Kimberly J, Spence, Philip J, Sattabongkot, Jetsumon, Biswas, Sumi, Rayner, Julian C, Draper, Simon J
Published in JCI insight (08.12.2021)
Published in JCI insight (08.12.2021)
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Journal Article
Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue
Rysnik, Oliwia, McHugh, Kirsty, van Duivenvoorde, Leonie, van Tok, Melissa, Taurog, Joel, Kollnberger, Simon, Baeten, Dominique, Bowness, Paul
Published in Data in brief (01.12.2016)
Published in Data in brief (01.12.2016)
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Journal Article
Regulation of Hepcidin by Erythropoiesis: The Story So Far
Pasricha, Sant-Rayn, McHugh, Kirsty, Drakesmith, Hal
Published in Annual review of nutrition (17.07.2016)
Published in Annual review of nutrition (17.07.2016)
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Journal Article
Characterizing the Plasma IgG Antibody Repertoire of Malaria-Naïve United Kingdom Adults Vaccinated with Novel Blood Stage Vaccine RH5.1/AS01 B
Marchioni, Jeffrey, Seeger, Allison, Barrett, Jordan R, McHugh, Kirsty, Kain, Jessica, MacGill, Randall, Georgiou, George, Draper, Simon J, Lavinder, Jason J, Ippolito, Gregory C
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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Journal Article
Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia
Arezes, João, Foy, Niall, McHugh, Kirsty, Quinkert, Doris, Benard, Susan, Sawant, Anagha, Frost, Joe N., Armitage, Andrew E., Pasricha, Sant-Rayn, Lim, Pei Jin, Tam, May S., Lavallie, Edward, Pittman, Debra D., Cunningham, Orla, Lambert, Matthew, Murphy, John E., Draper, Simon J., Jasuja, Reema, Drakesmith, Hal
Published in Blood (20.02.2020)
Published in Blood (20.02.2020)
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Journal Article
KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis
Wong-Baeza, Isabel, Ridley, Anna, Shaw, Jackie, Hatano, Hiroko, Rysnik, Oliwia, McHugh, Kirsty, Piper, Christopher, Brackenbridge, Simon, Fernandes, Ricardo, Chan, Anthoni, Bowness, Paul, Kollnberger, Simon
Published in The Journal of immunology (1950) (01.04.2013)
Published in The Journal of immunology (1950) (01.04.2013)
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Journal Article
Salmonella exploits HLA-B27 and host unfolded protein responses to promote intracellular replication
Antoniou, Antony Nicodemus, Lenart, Izabela, Kriston-Vizi, Janos, Iwawaki, Takao, Turmaine, Mark, McHugh, Kirsty, Ali, Sadfer, Blake, Neil, Bowness, Paul, Bajaj-Elliott, Mona, Gould, Keith, Nesbeth, Darren, Powis, Simon J
Published in Annals of the rheumatic diseases (01.01.2019)
Published in Annals of the rheumatic diseases (01.01.2019)
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Journal Article
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5
Wang, Lawrence T., Cooper, Andrew J.R., Farrell, Brendan, Miura, Kazutoyo, Diouf, Ababacar, Müller-Sienerth, Nicole, Crosnier, Cécile, Purser, Lauren, Kirtley, Payton J., Maciuszek, Maciej, Barrett, Jordan R., McHugh, Kirsty, Ogwang, Rodney, Tucker, Courtney, Li, Shanping, Doumbo, Safiatou, Doumtabe, Didier, Pyo, Chul-Woo, Skinner, Jeff, Nielsen, Carolyn M., Silk, Sarah E., Kayentao, Kassoum, Ongoiba, Aissata, Zhao, Ming, Nguyen, Doan C., Lee, F. Eun-Hyung, Minassian, Angela M., Geraghty, Daniel E., Traore, Boubacar, Seder, Robert A., Wilder, Brandon K., Crompton, Peter D., Wright, Gavin J., Long, Carole A., Draper, Simon J., Higgins, Matthew K., Tan, Joshua
Published in Cell (05.09.2024)
Published in Cell (05.09.2024)
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