Multiplexed analysis of chromosome conformation at vastly improved sensitivity
Davies, James O J, Telenius, Jelena M, McGowan, Simon J, Roberts, Nigel A, Taylor, Stephen, Higgs, Douglas R, Hughes, Jim R
Published in Nature methods (01.01.2016)
Published in Nature methods (01.01.2016)
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Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging
Stewart, Isabelle, Radtke, Daniel, Phillips, Bethan, McGowan, Simon J., Bannard, Oliver
Published in Immunity (Cambridge, Mass.) (18.09.2018)
Published in Immunity (Cambridge, Mass.) (18.09.2018)
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Germinal centers output clonally diverse plasma cell populations expressing high- and low-affinity antibodies
Sprumont, Adrien, Rodrigues, Ana, McGowan, Simon J., Bannard, Colin, Bannard, Oliver
Published in Cell (07.12.2023)
Published in Cell (07.12.2023)
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Intragenic Enhancers Act as Alternative Promoters
Kowalczyk, Monika S., Hughes, Jim R., Garrick, David, Lynch, Magnus D., Sharpe, Jacqueline A., Sloane-Stanley, Jacqueline A., McGowan, Simon J., De Gobbi, Marco, Hosseini, Mona, Vernimmen, Douglas, Brown, Jill M., Gray, Nicola E., Collavin, Licio, Gibbons, Richard J., Flint, Jonathan, Taylor, Stephen, Buckle, Veronica J., Milne, Thomas A., Wood, William G., Higgs, Douglas R.
Published in Molecular cell (24.02.2012)
Published in Molecular cell (24.02.2012)
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Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment
Hughes, Jim R, Roberts, Nigel, McGowan, Simon, Hay, Deborah, Giannoulatou, Eleni, Lynch, Magnus, De Gobbi, Marco, Taylor, Stephen, Gibbons, Richard, Higgs, Douglas R
Published in Nature genetics (01.02.2014)
Published in Nature genetics (01.02.2014)
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A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis
Schwerd, Tobias, Twigg, Stephen R F, Aschenbrenner, Dominik, Manrique, Santiago, Miller, Kerry A, Taylor, Indira B, Capitani, Melania, McGowan, Simon J, Sweeney, Elizabeth, Weber, Astrid, Chen, Liye, Bowness, Paul, Riordan, Andrew, Cant, Andrew, Freeman, Alexandra F, Milner, Joshua D, Holland, Steven M, Frede, Natalie, Müller, Miryam, Schmidt-Arras, Dirk, Grimbacher, Bodo, Wall, Steven A, Jones, E Yvonne, Wilkie, Andrew O M, Uhlig, Holm H
Published in The Journal of experimental medicine (04.09.2017)
Published in The Journal of experimental medicine (04.09.2017)
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CSynth: an interactive modelling and visualization tool for 3D chromatin structure
Todd, Stephen, Todd, Peter, McGowan, Simon J, Hughes, James R, Kakui, Yasutaka, Leymarie, Frederic Fol, Latham, William, Taylor, Stephen
Published in Bioinformatics (17.05.2021)
Published in Bioinformatics (17.05.2021)
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A Noncoding Expansion in EIF4A3 Causes Richieri-Costa-Pereira Syndrome, a Craniofacial Disorder Associated with Limb Defects
Favaro, Francine P., Alvizi, Lucas, Zechi-Ceide, Roseli M., Bertola, Debora, Felix, Temis M., de Souza, Josiane, Raskin, Salmo, Twigg, Stephen R.F., Weiner, Andrea M.J., Armas, Pablo, Margarit, Ezequiel, Calcaterra, Nora B., Andersen, Gregers R., McGowan, Simon J., Wilkie, Andrew O.M., Richieri-Costa, Antonio, de Almeida, Maria L.G., Passos-Bueno, Maria Rita
Published in American journal of human genetics (02.01.2014)
Published in American journal of human genetics (02.01.2014)
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Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses
Bannard, Oliver, McGowan, Simon J, Ersching, Jonatan, Ishido, Satoshi, Victora, Gabriel D, Shin, Jeoung-Sook, Cyster, Jason G
Published in The Journal of experimental medicine (30.05.2016)
Published in The Journal of experimental medicine (30.05.2016)
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Mutations in DPAGT1 Cause a Limb-Girdle Congenital Myasthenic Syndrome with Tubular Aggregates
Belaya, Katsiaryna, Finlayson, Sarah, Slater, Clarke R., Cossins, Judith, Liu, Wei Wei, Maxwell, Susan, McGowan, Simon J., Maslau, Siarhei, Twigg, Stephen R.F., Walls, Timothy J., Pascual Pascual, Samuel I., Palace, Jacqueline, Beeson, David
Published in American journal of human genetics (13.07.2012)
Published in American journal of human genetics (13.07.2012)
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Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors
May, Gillian, Soneji, Shamit, Tipping, Alex J., Teles, Jose, McGowan, Simon J., Wu, Mengchu, Guo, Yanping, Fugazza, Cristina, Brown, John, Karlsson, Göran, Pina, Cristina, Olariu, Victor, Taylor, Stephen, Tenen, Daniel G., Peterson, Carsten, Enver, Tariq
Published in Cell stem cell (05.12.2013)
Published in Cell stem cell (05.12.2013)
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Visualizing the origins of selfish de novo mutations in individual seminiferous tubules of human testes
Maher, Geoffrey J., McGowan, Simon J., Giannoulatou, Eleni, Verrill, Clare, Goriely, Anne, Wilkie, Andrew O. M.
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2016)
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Diagnostic value of exome and whole genome sequencing in craniosynostosis
Miller, Kerry A, Twigg, Stephen R F, McGowan, Simon J, Phipps, Julie M, Fenwick, Aimée L, Johnson, David, Wall, Steven A, Noons, Peter, Rees, Katie E M, Tidey, Elizabeth A, Craft, Judith, Taylor, John, Taylor, Jenny C, Goos, Jacqueline A C, Swagemakers, Sigrid M A, Mathijssen, Irene M J, van der Spek, Peter J, Lord, Helen, Lester, Tracy, Abid, Noina, Cilliers, Deirdre, Hurst, Jane A, Morton, Jenny E V, Sweeney, Elizabeth, Weber, Astrid, Wilson, Louise C, Wilkie, Andrew O M
Published in Journal of medical genetics (01.04.2017)
Published in Journal of medical genetics (01.04.2017)
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Congenital myasthenic syndromes due to mutations in ALG2 and ALG14
COSSINS, Judith, BELAYA, Katsiaryna, LAVAL, Steven, ZAIN SEIDHAMED, Mohammed, DONNELLY, Peter, BENTLEY, David, MCGOWAN, Simon J, MÜLLER, Juliane, PALACE, Jacqueline, LOCHMÜLLER, Hanns, BEESON, David, HICKS, Debbie, SALIH, Mustafa A, FINLAYSON, Sarah, CARBONI, Nicola, WEI WEI LIU, MAXWELL, Susan, ZOLTOWSKA, Katarzyna, TORABI FARSANI, Golara
Published in Brain (London, England : 1878) (01.03.2013)
Published in Brain (London, England : 1878) (01.03.2013)
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Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells
Kassouf, Mira T, Hughes, Jim R, Taylor, Stephen, McGowan, Simon J, Soneji, Shamit, Green, Angela L, Vyas, Paresh, Porcher, Catherine
Published in Genome research (01.08.2010)
Published in Genome research (01.08.2010)
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CPFP: a central proteomics facilities pipeline
Trudgian, David C., Thomas, Benjamin, McGowan, Simon J., Kessler, Benedikt M., Salek, Mogjiborahman, Acuto, Oreste
Published in Bioinformatics (15.04.2010)
Published in Bioinformatics (15.04.2010)
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Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints
Schwessinger, Ron, Suciu, Maria C, McGowan, Simon J, Telenius, Jelena, Taylor, Stephen, Higgs, Doug R, Hughes, Jim R
Published in Genome research (01.10.2017)
Published in Genome research (01.10.2017)
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BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome
Miller, Kerry A, Cruz Walma, David A, Pinkas, Daniel M, Tooze, Rebecca S, Bufton, Joshua C, Richardson, William, Manning, Charlotte E, Hunt, Alice E, Cros, Julien, Hartill, Verity, Parker, Michael J, McGowan, Simon J, Twigg, Stephen R F, Chalk, Rod, Staunton, David, Johnson, David, Wilkie, Andrew O M, Bullock, Alex N
Published in Journal of medical genetics (01.05.2024)
Published in Journal of medical genetics (01.05.2024)
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Gain-of-Function Mutations in ZIC1 Are Associated with Coronal Craniosynostosis and Learning Disability
Twigg, Stephen R.F., Forecki, Jennifer, Goos, Jacqueline A.C., Richardson, Ivy C.A., Hoogeboom, A. Jeannette M., van den Ouweland, Ans M.W., Swagemakers, Sigrid M.A., Lequin, Maarten H., Van Antwerp, Daniel, McGowan, Simon J., Westbury, Isabelle, Miller, Kerry A., Wall, Steven A., van der Spek, Peter J., Mathijssen, Irene M.J., Pauws, Erwin, Merzdorf, Christa S., Wilkie, Andrew O.M.
Published in American journal of human genetics (03.09.2015)
Published in American journal of human genetics (03.09.2015)
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Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors
Pfeifer, Susanne P, Hansen, Ruth M S, Olesen, Inge A, Meyts, Ewa Rajpert-De, Wilkie, Andrew O M, Goriely, Anne, McGowan, Simon J, Taylor, Indira B, McVean, Gilean A T, Jacobsen, Grete Krag
Published in Nature genetics (01.11.2009)
Published in Nature genetics (01.11.2009)
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