Increased blood-brain barrier hyperpermeability coincides with mast cell activation early under cuprizone administration
Shelestak, John, Singhal, Naveen, Frankle, Lana, Tomor, Riely, Sternbach, Sarah, McDonough, Jennifer, Freeman, Ernest, Clements, Robert
Published in PloS one (08.06.2020)
Published in PloS one (08.06.2020)
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3D Co‐culturing of human neuroblastoma and human oligodendrocytes, emulating native tissue using 3D porous biodegradable liquid crystal elastomers
Ustunel, Senay, Sternbach, Sarah, Prévôt, Marianne E., Freeman, Ernie J., McDonough, Jennifer A., Clements, Robert J., Hegmann, Elda
Published in Journal of applied polymer science (20.05.2023)
Published in Journal of applied polymer science (20.05.2023)
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Liquid Crystal Elastomer Microspheres as Three-Dimensional Cell Scaffolds Supporting the Attachment and Proliferation of Myoblasts
Bera, Tanmay, Freeman, Ernest J, McDonough, Jennifer A, Clements, Robert J, Aladlaan, Asaad, Miller, Donald W, Malcuit, Christopher, Hegmann, Torsten, Hegmann, Elda
Published in ACS applied materials & interfaces (08.07.2015)
Published in ACS applied materials & interfaces (08.07.2015)
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Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model
Guo, Fuzheng, Bannerman, Peter, Mills Ko, Emily, Miers, Laird, Xu, Jie, Burns, Travis, Li, Shuo, Freeman, Ernest, McDonough, Jennifer A., Pleasure, David
Published in Annals of neurology (01.05.2015)
Published in Annals of neurology (01.05.2015)
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The BHMT-betaine methylation pathway epigenetically modulates oligodendrocyte maturation
Sternbach, Sarah, West, Nicole, Singhal, Naveen K, Clements, Robert, Basu, Soumitra, Tripathi, Ajai, Dutta, Ranjan, Freeman, Ernest J, McDonough, Jennifer
Published in PloS one (11.05.2021)
Published in PloS one (11.05.2021)
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Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy
Sohn, Jiho, Bannerman, Peter, Guo, Fuzheng, Burns, Travis, Miers, Laird, Croteau, Christopher, Singhal, Naveen K, McDonough, Jennifer A, Pleasure, David
Published in The Journal of neuroscience (11.01.2017)
Published in The Journal of neuroscience (11.01.2017)
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Journal Article
Suppressing N -Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy
Sohn, Jiho, Bannerman, Peter, Guo, Fuzheng, Burns, Travis, Miers, Laird, Croteau, Christopher, Singhal, Naveen K., McDonough, Jennifer A., Pleasure, David
Published in The Journal of neuroscience (11.01.2017)
Published in The Journal of neuroscience (11.01.2017)
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Journal Article
Brain Nat8l Knockdown Suppresses Spongiform Leukodystrophy in an Aspartoacylase-Deficient Canavan Disease Mouse Model
Bannerman, Peter, Guo, Fuzheng, Chechneva, Olga, Burns, Travis, Zhu, Xiaoqing, Wang, Yan, Kim, Bokyung, Singhal, Naveen K., McDonough, Jennifer A., Pleasure, David
Published in Molecular therapy (07.03.2018)
Published in Molecular therapy (07.03.2018)
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Neuronal Hemoglobin Expression and Its Relevance to Multiple Sclerosis Neuropathology
Brown, Nolan, Alkhayer, Kholoud, Clements, Robert, Singhal, Naveen, Gregory, Roger, Azzam, Sausan, Li, Shuo, Freeman, Ernest, McDonough, Jennifer
Published in Journal of molecular neuroscience (01.05.2016)
Published in Journal of molecular neuroscience (01.05.2016)
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Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients
Dutta, Ranjan, McDonough, Jennifer, Yin, Xinghua, Peterson, John, Chang, Ansi, Torres, Thalia, Gudz, Tatyana, Macklin, Wendy B., Lewis, David A., Fox, Robert J., Rudick, Richard, Mirnics, Karoly, Trapp, Bruce D.
Published in Annals of neurology (01.03.2006)
Published in Annals of neurology (01.03.2006)
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Journal Article
Vitamin K enhances the production of brain sulfatides during remyelination
Popescu, Daniela C, Huang, He, Singhal, Naveen K, Shriver, Leah, McDonough, Jennifer, Clements, Robert J, Freeman, Ernest J
Published in PloS one (27.08.2018)
Published in PloS one (27.08.2018)
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Journal Article
Betaine restores epigenetic control and supports neuronal mitochondria in the cuprizone mouse model of multiple sclerosis
Singhal, Naveen K., Sternbach, Sarah, Fleming, Sheila, Alkhayer, Kholoud, Shelestak, John, Popescu, Daniela, Weaver, Alyx, Clements, Robert, Wasek, Brandi, Bottiglieri, Teodoro, Freeman, Ernest J., McDonough, Jennifer
Published in Epigenetics (02.08.2020)
Published in Epigenetics (02.08.2020)
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The epigenetic signatures of opioid addiction and physical dependence are prevented by D-cysteine ethyl ester and betaine
McDonough, Jennifer, Singhal, Naveen K, Getsy, Paulina M, Knies, Katherine, Knauss, Zackery T, Mueller, Devin, Bates, James N, Damron, Derek S, Lewis, Stephen J
Published in Frontiers in pharmacology (30.08.2024)
Published in Frontiers in pharmacology (30.08.2024)
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Effects of Structural Variations on the Cellular Response and Mechanical Properties of Biocompatible, Biodegradable, and Porous Smectic Liquid Crystal Elastomers
Sharma, Anshul, Mori, Taizo, Mahnen, Cory J., Everson, Heather R., Leslie, Michelle T., Nielsen, Alek d., Lussier, Laurent, Zhu, Chenhui, Malcuit, Christopher, Hegmann, Torsten, McDonough, Jennifer A., Freeman, Ernest J., Korley, LaShanda T. J., Clements, Robert J., Hegmann, Elda
Published in Macromolecular bioscience (01.02.2017)
Published in Macromolecular bioscience (01.02.2017)
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Journal Article
Tumor antigen CA125 suppresses antibody-dependent cellular cytotoxicity (ADCC) via direct antibody binding and suppressed Fc-γ receptor engagement
Kline, James Bradford, Kennedy, Rina P, Albone, Earl, Chao, Qimin, Fernando, Shawn, McDonough, Jennifer M, Rybinski, Katherine, Wang, Wenquan, Somers, Elizabeth B, Schweizer, Charles, Grasso, Luigi, Nicolaides, Nicholas C
Published in Oncotarget (08.08.2017)
Published in Oncotarget (08.08.2017)
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Journal Article
Analysis of the mitochondrial proteome in multiple sclerosis cortex
Broadwater, Laurie, Pandit, Ashish, Clements, Robert, Azzam, Sausan, Vadnal, Jonathan, Sulak, Michael, Yong, V. Wee, Freeman, Ernest J., Gregory, Roger B., McDonough, Jennifer
Published in Biochimica et biophysica acta (01.05.2011)
Published in Biochimica et biophysica acta (01.05.2011)
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Journal Article
Biocompatible, Biodegradable and Porous Liquid Crystal Elastomer Scaffolds for Spatial Cell Cultures
Sharma, Anshul, Neshat, Abdollah, Mahnen, Cory J., Nielsen, Alek d., Snyder, Jacob, Stankovich, Tory L., Daum, Benjamin G., LaSpina, Emily M., Beltrano, Gabrielle, Gao, Yunxiang, Li, Shuo, Park, Byung-Wook, Clements, Robert J., Freeman, Ernest J., Malcuit, Christopher, McDonough, Jennifer A., Korley, LaShanda T. J., Hegmann, Torsten, Hegmann, Elda
Published in Macromolecular bioscience (01.02.2015)
Published in Macromolecular bioscience (01.02.2015)
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Journal Article
Astroglial conditional Slc13a3 knockout is therapeutic in murine Canavan leukodystrophy
Hull, Vanessa L., Wang, Yan, McDonough, Jennifer, Zhu, Meina, Burns, Travis, Al Ramel, Najmah, Dehghani, Ali, Guo, Fuzheng, Pleasure, David
Published in Annals of clinical and translational neurology (01.04.2024)
Published in Annals of clinical and translational neurology (01.04.2024)
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