Modelling a Human Blood-Brain Barrier Co-Culture Using an Ultrathin Silicon Nitride Membrane-Based Microfluidic Device
Hudecz, Diana, McCloskey, Molly C, Vergo, Sandra, Christensen, Søren, McGrath, James L, Nielsen, Morten S
Published in International journal of molecular sciences (15.03.2023)
Published in International journal of molecular sciences (15.03.2023)
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Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection
Arnold, Samuel L. M., Choi, Ryan, Hulverson, Matthew A., Schaefer, Deborah A., Vinayak, Sumiti, Vidadala, Rama S. R., McCloskey, Molly C., Whitman, Grant R., Huang, Wenlin, Barrett, Lynn K., Ojo, Kayode K., Fan, Erkang, Maly, Dustin J., Riggs, Michael W., Striepen, Boris, Van Voorhis, Wesley C.
Published in The Journal of infectious diseases (01.07.2017)
Published in The Journal of infectious diseases (01.07.2017)
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Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum
Hennessey, Kelly M, Rogiers, Ilse C, Shih, Han-Wei, Hulverson, Matthew A, Choi, Ryan, McCloskey, Molly C, Whitman, Grant R, Barrett, Lynn K, Merritt, Ethan A, Paredez, Alexander R, Ojo, Kayode K
Published in PLoS neglected tropical diseases (01.08.2018)
Published in PLoS neglected tropical diseases (01.08.2018)
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Journal Article
Molecular mechanisms underlying the heterogeneous barrier responses of two primary endothelial cell types to sphingosine-1-phosphate
Salminen, Alec T., McCloskey, Molly C., Ahmad, S. Danial, Romanick, Samantha S., Chen, Kaihua, Houlihan, William, Klaczko, Michael E., Flax, Jonathan, Waugh, Richard E., McGrath, James L.
Published in European journal of cell biology (01.06.2022)
Published in European journal of cell biology (01.06.2022)
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Journal Article
The Modular µSiM Reconfigured: Integration of Microfluidic Capabilities to Study In Vitro Barrier Tissue Models under Flow
Mansouri, Mehran, Ahmed, Adeel, Ahmad, S Danial, McCloskey, Molly C, Joshi, Indranil M, Gaborski, Thomas R, Waugh, Richard E, McGrath, James L, Day, Steven W, Abhyankar, Vinay V
Published in Advanced healthcare materials (01.11.2022)
Published in Advanced healthcare materials (01.11.2022)
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Journal Article
The Modular µSiM: A Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro
McCloskey, Molly C, Kasap, Pelin, Ahmad, S Danial, Su, Shiuan-Haur, Chen, Kaihua, Mansouri, Mehran, Ramesh, Natalie, Nishihara, Hideaki, Belyaev, Yury, Abhyankar, Vinay V, Begolo, Stefano, Singer, Benjamin H, Webb, Kevin F, Kurabayashi, Katsuo, Flax, Jonathan, Waugh, Richard E, Engelhardt, Britta, McGrath, James L
Published in Advanced healthcare materials (01.09.2022)
Published in Advanced healthcare materials (01.09.2022)
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Journal Article
Microvascular Mimetics for the Study of Leukocyte–Endothelial Interactions
Khire, Tejas S., Salminen, Alec T., Swamy, Harsha, Lucas, Kilean S., McCloskey, Molly C., Ajalik, Raquel E., Chung, Henry H., Gaborski, Thomas R., Waugh, Richard E., Glading, Angela J., McGrath, James L.
Published in Cellular and molecular bioengineering (01.04.2020)
Published in Cellular and molecular bioengineering (01.04.2020)
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Journal Article
A tissue chip with integrated digital immunosensors: In situ brain endothelial barrier cytokine secretion monitoring
Su, Shiuan-Haur, Song, Yujing, Stephens, Andrew, Situ, Muyu, McCloskey, Molly C., McGrath, James L., Andjelkovic, Anuska V., Singer, Benjamin H., Kurabayashi, Katsuo
Published in Biosensors & bioelectronics (15.03.2023)
Published in Biosensors & bioelectronics (15.03.2023)
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Journal Article
Rapid and specific detection of intact viral particles using functionalized microslit silicon membranes as a fouling-based sensor
Klaczko, Michael E, Lucas, Kilean, Salminen, Alec T, McCloskey, Molly C, Ozgurun, Baturay, Ward, Brian M, Flax, Jonathan, McGrath, James L
Published in Analyst (London) (17.01.2022)
Published in Analyst (London) (17.01.2022)
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Journal Article
Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosis
Müller, Joachim, Aguado-Martínez, Adriana, Ortega-Mora, Luis-Miguel, Moreno-Gonzalo, Javier, Ferre, Ignacio, Hulverson, Matthew A, Choi, Ryan, McCloskey, Molly C, Barrett, Lynn K, Maly, Dustin J, Ojo, Kayode K, Van Voorhis, Wes, Hemphill, Andrew
Published in Journal of antimicrobial chemotherapy (01.08.2017)
Published in Journal of antimicrobial chemotherapy (01.08.2017)
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Journal Article
Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned
Choi, Ryan, Hulverson, Matthew A., Huang, Wenlin, Vidadala, Rama S.R., Whitman, Grant R., Barrett, Lynn K., Schaefer, Deborah A., Betzer, Dana P., Riggs, Michael W., Doggett, J. Stone, Hemphill, Andrew, Ortega-Mora, Luis Miguel, McCloskey, Molly C., Arnold, Samuel L.M., Hackman, Robert C., Marsh, Kennan C., Lynch, James J., Freiberg, Gail M., Leroy, Bruce E., Kempf, Dale J., Choy, Robert K.M., de Hostos, Eugenio L., Maly, Dustin J., Fan, Erkang, Ojo, Kayode K., Van Voorhis, Wesley C.
Published in International journal for parasitology (01.05.2020)
Published in International journal for parasitology (01.05.2020)
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Journal Article
Development of 5‑Aminopyrazole-4-carboxamide-based Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy
Huang, Wenlin, Hulverson, Matthew A, Choi, Ryan, Arnold, Samuel L. M, Zhang, Zhongsheng, McCloskey, Molly C, Whitman, Grant R, Hackman, Robert C, Rivas, Kasey L, Barrett, Lynn K, Ojo, Kayode K, Van Voorhis, Wesley C, Fan, Erkang
Published in Journal of medicinal chemistry (28.03.2019)
Published in Journal of medicinal chemistry (28.03.2019)
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Journal Article
Use of the MicroSiM (µSiM) Barrier Tissue Platform for Modeling the Blood-Brain Barrier
McCloskey, Molly C, Kasap, Pelin, Trempel, Michelle, Widom, Louis P, Kuebel, Julia, Chen, Kaihua, Gaborski, Thomas R, Engelhardt, Britta, McGrath, James L
Published in Journal of visualized experiments (12.01.2024)
Published in Journal of visualized experiments (12.01.2024)
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Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis
Hulverson, Matthew A, Choi, Ryan, Schaefer, Deborah A, Betzer, Dana P, McCloskey, Molly C, Whitman, Grant R, Huang, Wenlin, Lee, Sangun, Pranata, Andy, McLeod, Malcolm D, Marsh, Kennan C, Kempf, Dale J, LeRoy, Bruce E, Zafiratos, Mark T, Bielinski, Aimee L, Hackman, Robert C, Ojo, Kayode K, Arnold, Samuel L M, Barrett, Lynn K, Tzipori, Saul, Riggs, Michael W, Fan, Erkang, Van Voorhis, Wesley C
Published in Antimicrobial agents and chemotherapy (18.04.2023)
Published in Antimicrobial agents and chemotherapy (18.04.2023)
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Journal Article
P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium
Arnold, Samuel L M, Choi, Ryan, Hulverson, Matthew A, Whitman, Grant R, Mccloskey, Molly C, Dorr, Carlie S, Vidadala, Rama S R, Khatod, Mansi, Morada, Mary, Barrett, Lynn K, Maly, Dustin J, Yarlett, Nigel, Van Voorhis, Wesley C
Published in The Journal of infectious diseases (30.08.2019)
Published in The Journal of infectious diseases (30.08.2019)
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Journal Article
Author Correction: Evaluation of in vitro and in vivo antibiotic efficacy against a novel bioluminescent Shigella flexneri
McCloskey, Molly C., Shaheen, Shareef, Rabago, Lesley, Hulverson, Matthew A., Choi, Ryan, Barrett, Lynn K., Arnold, Samuel L. M.
Published in Scientific reports (11.02.2020)
Published in Scientific reports (11.02.2020)
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Journal Article
Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis
Hulverson, Matthew A, Bruzual, Igor, McConnell, Erin V, Huang, Wenlin, Vidadala, Rama S R, Choi, Ryan, Arnold, Samuel L M, Whitman, Grant R, McCloskey, Molly C, Barrett, Lynn K, Rivas, Kasey L, Scheele, Suzanne, DeRocher, Amy E, Parsons, Marilyn, Ojo, Kayode K, Maly, Dustin J, Fan, Erkang, Van Voorhis, Wesley C, Doggett, J Stone
Published in The Journal of infectious diseases (16.04.2019)
Published in The Journal of infectious diseases (16.04.2019)
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Journal Article
Evaluation of in vitro and in vivo antibiotic efficacy against a novel bioluminescent Shigella flexneri
McCloskey, Molly C., Shaheen, Shareef, Rabago, Lesley, Hulverson, Matthew A., Choi, Ryan, Barrett, Lynn K., Arnold, Samuel L. M.
Published in Scientific reports (19.09.2019)
Published in Scientific reports (19.09.2019)
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Journal Article
Endothelial cell apicobasal polarity coordinates distinct responses to luminally versus abluminally delivered TNF-α in a microvascular mimetic
Salminen, Alec T, Tithof, Jeffrey, Izhiman, Yara, Masters, Elysia A, McCloskey, Molly C, Gaborski, Thomas R, Kelley, Douglas H, Pietropaoli, Anthony P, Waugh, Richard E, McGrath, James L
Published in Integrative biology (Cambridge) (18.11.2020)
Published in Integrative biology (Cambridge) (18.11.2020)
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