Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF
Mercer, Paul F, Woodcock, Hannah V, Eley, Jessica D, Platé, Manuela, Sulikowski, Michal G, Durrenberger, Pascal F, Franklin, Linda, Nanthakumar, Carmel B, Man, Yim, Genovese, Federica, McAnulty, Robin J, Yang, Shuying, Maher, Toby M, Nicholson, Andrew G, Blanchard, Andy D, Marshall, Richard P, Lukey, Pauline T, Chambers, Rachel C
Published in Thorax (01.08.2016)
Published in Thorax (01.08.2016)
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Journal Article
Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis
Evans, Iona C, Barnes, Josephine L, Garner, Ian M, Pearce, David R, Maher, Toby M, Shiwen, Xu, Renzoni, Elisabetta A, Wells, Athol U, Denton, Christopher P, Laurent, Geoffrey J, Abraham, David J, McAnulty, Robin J
Published in Clinical science (1979) (01.04.2016)
Published in Clinical science (1979) (01.04.2016)
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Journal Article
Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis
Manunta, Maria D. I., Tagalakis, Aristides D., Attwood, Martin, Aldossary, Ahmad M., Barnes, Josephine L., Munye, Mustafa M., Weng, Alexander, McAnulty, Robin J, Hart, Stephen L.
Published in Scientific reports (06.04.2017)
Published in Scientific reports (06.04.2017)
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Journal Article
Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells
Patel, Jigisha A, Shen, Lei, Hall, Susan M, Benyahia, Chabha, Norel, Xavier, McAnulty, Robin J, Moledina, Shahin, Silverstein, Adam M, Whittle, Brendan J, Clapp, Lucie H
Published in International journal of molecular sciences (12.08.2018)
Published in International journal of molecular sciences (12.08.2018)
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Journal Article
Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma
Bottoms, Stephen E, Howell, Jane E, Reinhardt, Alistair K, Evans, Iona C, McAnulty, Robin J
Published in PloS one (12.03.2010)
Published in PloS one (12.03.2010)
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Journal Article
Pulmonary Epithelium Is a Prominent Source of Proteinase-activated Receptor-1-inducible CCL2 in Pulmonary Fibrosis
Mercer, Paul F, Johns, Robin H, Scotton, Chris J, Krupiczojc, Malvina A, Konigshoff, Melanie, Howell, David C. J, McAnulty, Robin J, Das, Anuk, Thorley, Andrew J, Tetley, Terry D, Eickelberg, Oliver, Chambers, Rachel C
Published in American journal of respiratory and critical care medicine (01.03.2009)
Published in American journal of respiratory and critical care medicine (01.03.2009)
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Journal Article
Angiotensin II and the fibroproliferative response to acute lung injury
Marshall, Richard P, Gohlke, Peter, Chambers, Rachel C, Howell, David C, Bottoms, Steve E, Unger, Thomas, McAnulty, Robin J, Laurent, Geoffrey J
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2004)
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2004)
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Journal Article
Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium
Manunta, Maria D I, McAnulty, Robin J, Tagalakis, Aristides D, Bottoms, Stephen E, Campbell, Frederick, Hailes, Helen C, Tabor, Alethea B, Laurent, Geoffrey J, O'Callaghan, Christopher, Hart, Stephen L
Published in PloS one (26.10.2011)
Published in PloS one (26.10.2011)
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Journal Article
Fibroproliferation occurs early in the acute respiratory distress syndrome and impacts on outcome
MARSHALL, Richard P, BELLINGAN, Geoffrey, WEBB, Suzanne, PUDDICOMBE, Anna, GOLDSACK, Neil, MCANULTY, Robin J, LAURENT, Geoffrey J
Published in American journal of respiratory and critical care medicine (01.11.2000)
Published in American journal of respiratory and critical care medicine (01.11.2000)
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Journal Article
Reduced SOCS1 Expression in Lung Fibroblasts from Patients with IPF Is Not Mediated by Promoter Methylation or Mir155
Prêle, Cecilia M, Iosifidis, Thomas, McAnulty, Robin J, Pearce, David R, Badrian, Bahareh, Miles, Tylah, Jamieson, Sarra E, Ernst, Matthias, Thompson, Philip J, Laurent, Geoffrey J, Knight, Darryl A, Mutsaers, Steven E
Published in Biomedicines (30.04.2021)
Published in Biomedicines (30.04.2021)
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Journal Article
Inverse Effects of Interleukin-6 on Apoptosis of Fibroblasts from Pulmonary Fibrosis and Normal Lungs
Moodley, Yuben P, Misso, Neil L. A, Scaffidi, Amelia K, Fogel-Petrovic, Mirjana, McAnulty, Robin J, Laurent, Geoffrey J, Thompson, Philip J, Knight, Darryl A
Published in American journal of respiratory cell and molecular biology (01.10.2003)
Published in American journal of respiratory cell and molecular biology (01.10.2003)
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Journal Article
Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices
Tatler, Amanda L, Barnes, Josephine, Habgood, Anthony, Goodwin, Amanda, McAnulty, Robin J, Jenkins, Gisli
Published in Thorax (01.06.2016)
Published in Thorax (01.06.2016)
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Journal Article
Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2
Akers, Ian A, Parsons, Maddy, Hill, Michael R, Hollenberg, Morley D, Sanjar, Shahin, Laurent, Geoffrey J, McAnulty, Robin J
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2000)
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2000)
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Journal Article
Direct Thrombin Inhibition Reduces Lung Collagen, Accumulation, and Connective Tissue Growth Factor mRNA Levels in Bleomycin-Induced Pulmonary Fibrosis
Howell, David C.J., Goldsack, Neil R., Marshall, Richard P., McAnulty, Robin J., Starke, Richard, Purdy, Gordon, Laurent, Geoffrey J., Chambers, Rachel C.
Published in The American journal of pathology (01.10.2001)
Published in The American journal of pathology (01.10.2001)
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Journal Article
Plasma cell but not CD20-mediated B-cell depletion protects from bleomycin-induced lung fibrosis
Prêle, Cecilia M., Miles, Tylah, Pearce, David R., O'Donoghue, Robert J., Grainge, Chris, Barrett, Lucy, Birnie, Kimberly, Lucas, Andrew D., Baltic, Svetlana, Ernst, Matthias, Rinaldi, Catherine, Laurent, Geoffrey J., Knight, Darryl A., Fear, Mark, Hoyne, Gerard, McAnulty, Robin J., Mutsaers, Steven E.
Published in The European respiratory journal (01.11.2022)
Published in The European respiratory journal (01.11.2022)
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Journal Article
Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis
Guillotin, Delphine, Taylor, Adam R, Platé, Manuela, Mercer, Paul F, Edwards, Lindsay M, Haggart, Ross, Miele, Gino, McAnulty, Robin J, Maher, Toby M, Hynds, Robert E, Jamal-Hanjani, Mariam, Marshall, Richard P, Fisher, Andrew J, Blanchard, Andy D, Chambers, Rachel C
Published in Thorax (01.01.2021)
Published in Thorax (01.01.2021)
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Journal Article
Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts
Scaffidi, Amelia K, Mutsaers, Steven E, Moodley, Yuben P, McAnulty, Robin J, Laurent, Geoffrey J, Thompson, Philip J, Knight, Darryl A
Published in British journal of pharmacology (01.07.2002)
Published in British journal of pharmacology (01.07.2002)
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Journal Article
Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung
Tagalakis, Aristides D, Munye, Mustafa M, Ivanova, Rositsa, Chen, Hanpeng, Smith, Claire M, Aldossary, Ahmad M, Rosa, Luca Z, Moulding, Dale, Barnes, Josephine L, Kafetzis, Konstantinos N, Jones, Stuart A, Baines, Deborah L, Moss, Guy W J, O’Callaghan, Christopher, McAnulty, Robin J, Hart, Stephen L
Published in Thorax (01.09.2018)
Published in Thorax (01.09.2018)
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