The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins
Deora, Vandana, Lee, John D., Albornoz, Eduardo A., McAlary, Luke, Jagaraj, Cyril J., Robertson, Avril A. B., Atkin, Julie D., Cooper, Matthew A., Schroder, Kate, Yerbury, Justin J., Gordon, Richard, Woodruff, Trent M.
Published in Glia (01.02.2020)
Published in Glia (01.02.2020)
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Journal Article
SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS
Farrawell, Natalie E., Lambert-Smith, Isabella, Mitchell, Kristen, McKenna, Jessie, McAlary, Luke, Ciryam, Prajwal, Vine, Kara L., Saunders, Darren N., Yerbury, Justin J.
Published in Journal of cell science (01.06.2018)
Published in Journal of cell science (01.06.2018)
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Journal Article
The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation
Capper, Michael J., Wright, Gareth S. A., Barbieri, Letizia, Luchinat, Enrico, Mercatelli, Eleonora, McAlary, Luke, Yerbury, Justin J., O’Neill, Paul M., Antonyuk, Svetlana V., Banci, Lucia, Hasnain, S. Samar
Published in Nature communications (27.04.2018)
Published in Nature communications (27.04.2018)
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Journal Article
Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection
Crown, Anthony, McAlary, Luke, Fagerli, Eric, Brown, Hilda, Yerbury, Justin J, Galaleldeen, Ahmad, Cashman, Neil R, Borchelt, David R, Ayers, Jacob I
Published in PloS one (30.01.2020)
Published in PloS one (30.01.2020)
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Journal Article
Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells
McAlary, Luke, Nan, Jeremy R, Shyu, Clay, Sher, Mine, Plotkin, Steven S, Cashman, Neil R
Published in Open biology (01.06.2024)
Published in Open biology (01.06.2024)
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Journal Article
CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background
Lum, Jeremy S., Brown, Mikayla L., Farrawell, Natalie E., McAlary, Luke, Ly, Diane, Chisholm, Christen G., Snow, Josh, Vine, Kara L., Karl, Tim, Kreilaus, Fabian, McInnes, Lachlan E., Nikseresht, Sara, Donnelly, Paul S., Crouch, Peter J., Yerbury, Justin J.
Published in Scientific reports (29.09.2021)
Published in Scientific reports (29.09.2021)
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Journal Article
Protocol for the generation and automated confocal imaging of whole multi-cellular tumor spheroids
Genenger, Benjamin, McAlary, Luke, Perry, Jay R., Ashford, Bruce, Ranson, Marie
Published in STAR protocols (16.06.2023)
Published in STAR protocols (16.06.2023)
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Journal Article
Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
Robert, Jerome, Button, Emily B, Martin, Emma M, McAlary, Luke, Gidden, Zoe, Gilmour, Megan, Boyce, Guilaine, Caffrey, Tara M, Agbay, Andrew, Clark, Amanda, Silverman, Judith M, Cashman, Neil R, Wellington, Cheryl L
Published in Molecular neurodegeneration (25.03.2020)
Published in Molecular neurodegeneration (25.03.2020)
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Journal Article
Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS
Farrawell, Natalie E., McAlary, Luke, Lum, Jeremy S., Chisholm, Christen G., Warraich, Sadaf T., Blair, Ian P., Vine, Kara L., Saunders, Darren N., Yerbury, Justin J.
Published in iScience (20.11.2020)
Published in iScience (20.11.2020)
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Journal Article
Assessment of protein inclusions in cultured cells using automated image analysis
McAlary, Luke, Shephard, Victoria K., Sher, Mine, Rice, Lauren J., Yerbury, Justin J., Cashman, Neil R., Plotkin, Steven S.
Published in STAR protocols (16.12.2022)
Published in STAR protocols (16.12.2022)
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Journal Article
Flow cytometric measurement of the cellular propagation of TDP-43 aggregation
Zeineddine, Rafaa, Whiten, Daniel R., Farrawell, Natalie E., McAlary, Luke, Hanspal, Maya A., Kumita, Janet R., Wilson, Mark R., Yerbury, Justin J.
Published in Prion (04.05.2017)
Published in Prion (04.05.2017)
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Journal Article
Proteome Homeostasis Dysfunction: A Unifying Principle in ALS Pathogenesis
Yerbury, Justin J., Farrawell, Natalie E., McAlary, Luke
Published in Trends in neurosciences (Regular ed.) (01.05.2020)
Published in Trends in neurosciences (Regular ed.) (01.05.2020)
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Journal Article