A pilot study of MBX-8025 in the treatment of homozygous familial hypercholesterolemia (HoFH)
Gaudet, D, Saheb, S, Bruckert, E, de Graaf, J, Langslet, G, Tardif, J.C, Bergheanu, S, Steinberg, A, Choi, Y.J, Martin, R, McWherter, C, Kastelein, J, Boudes, P
Published in Atherosclerosis (01.09.2016)
Published in Atherosclerosis (01.09.2016)
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A comparative analysis of the kinetic mechanism and peptide substrate specificity of human and Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase
Rocque, W.J., McWherter, C.A., Wood, D.C., Gordon, J.I.
Published in The Journal of biological chemistry (15.05.1993)
Published in The Journal of biological chemistry (15.05.1993)
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Novel Biologically Active Nonpeptidic Inhibitors of MyristoylCoA:Protein N-Myristoyltransferase
Devadas, Balekudru, Freeman, Sandra K, McWherter, Charles A, Kishore, Nandini S, Lodge, Jennifer K, Jackson-Machelski, Emily, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (12.03.1998)
Published in Journal of medicinal chemistry (12.03.1998)
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Kinetic and structural evidence for a sequential ordered Bi Bi mechanism of catalysis by Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase
RUDNICK, D. A, MCWHERTER, C. A, ROCQUE, W. J, LENNON, P. J, GETMAN, D. P, GORDON, J. I
Published in The Journal of biological chemistry (25.05.1991)
Published in The Journal of biological chemistry (25.05.1991)
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Design and Synthesis of Novel Imidazole-Substituted Dipeptide Amides as Potent and Selective Inhibitors of Candida albicans MyristoylCoA:Protein N-Myristoyltransferase and Identification of Related Tripeptide Inhibitors with Mechanism-Based Antifungal Activity
Devadas, Balekudru, Freeman, Sandra K, Zupec, Mark E, Lu, Hwang-Fun, Nagarajan, Srinivasan R, Kishore, Nandini S, Lodge, Jennifer K, Kuneman, David W, McWherter, Charles A, Vinjamoori, Dutt V, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (01.08.1997)
Published in Journal of medicinal chemistry (01.08.1997)
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Isothermal titration calorimetric studies of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase. Determinants of binding energy and catalytic discrimination among acyl-CoA and peptide ligands
Bhatnagar, R.S, Jackson-Machelski, E, McWherter, C.A, Gordon, J.I
Published in The Journal of biological chemistry (15.04.1994)
Published in The Journal of biological chemistry (15.04.1994)
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Conformationally Constrained [p-(ω-Aminoalkyl)phenacetyl]-l-seryl-l-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N-Myristoyl Transferase
Nagarajan, Srinivasan R, Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Lu, Hwang-Fun, Mehta, Pramod P, Kishore, Nandini S, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (09.05.1997)
Published in Journal of medicinal chemistry (09.05.1997)
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Design and Syntheses of Potent and Selective Dipeptide Inhibitors of Candida albicans Myristoyl-CoA:Protein N-Myristoyltransferase
Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Nagarajan, Srinivasan, Sikorski, James A, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I
Published in Journal of medicinal chemistry (01.05.1995)
Published in Journal of medicinal chemistry (01.05.1995)
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Multiple conformations of a human interleukin‐3 variant
Feng, Yiqing, Hood, William F., Forgey, Robert W., Abegg, Ann L., Caparon, Marie H., Thiele, Barrett R., Leimgruber, Richard M., Mcwherter, Charles A.
Published in Protein science (01.08.1997)
Published in Protein science (01.08.1997)
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Structural and functional studies of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase produced in Escherichia coli: Evidence for an acyl-enzyme intermediate
Rudnick, D.A. (Washington University School of Medicine, St. Louis, MO), McWherter, C.A, Adams, S.P, Ropson, I.J, Duronio, R.J, Gordon, J.I
Published in The Journal of biological chemistry (05.08.1990)
Published in The Journal of biological chemistry (05.08.1990)
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Three-dimensional Solution Structure and Backbone Dynamics of a Variant of Human Interleukin-3
Feng, Yiqing, Klein, Barbara K., McWherter, Charles A.
Published in Journal of molecular biology (14.06.1996)
Published in Journal of molecular biology (14.06.1996)
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Use of Photoactivatable Peptide Substrates of Saccharomyces cerevisiae Myristoyl-CoA:Protein N-Myristoyltransferase (Nmt1p) to Characterize a Myristoyl-CoA-Nmt1p-Peptide Ternary Complex and to Provide Evidence for an Ordered Reaction Mechanism
Rudnick, D A, Rocque, W J, McWherter, C A, Toth, M V, Jackson-Machelski, E, Gordon, J I
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.1993)
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Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent
Lodge, J K, Jackson-Machelski, E, Higgins, M, McWherter, C A, Sikorski, J A, Devadas, B, Gordon, J I
Published in The Journal of biological chemistry (15.05.1998)
Published in The Journal of biological chemistry (15.05.1998)
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THU-238 - Pharmacokinetics and pharmacodynamics of seladelpar, a potent and selective PPAR-delta, in patients with primary biliary cholangitis
Boudes, P., Michael, G., Bowlus, C., Hirschfield, G., Jones, D., Odin, J., Sheridan, D., Gitlin, N., Harrison, S., Hassanein, T., Levy, C., Shiffman, M., Thorburn, D., Thuluvath, P.J., Vierling, J., Choi, Y.-J., Varga, M., (Sasha) Steinberg, A., Mcwherter, C., Martin, R.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Pharmacokinetics and pharmacodynamics of seladelpar, a potent and selective PPAR-delta, in patients with primary biliary cholangitis
Boudes, P., Michael, G., Bowlus, C., Hirschfield, G., Jones, D., Odin, J., Sheridan, D., Gitlin, N., Harrison, S., Hassanein, T., Levy, C., Shiffman, M., Thorburn, D., Thuluvath, P.J., Vierling, J., Choi, Y.-J., Varga, M., (Sasha) Steinberg, A., Mcwherter, C., Martin, R.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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