TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells
Woznicki, Jerzy A., Saini, Nisha, Flood, Peter, Rajaram, Subhasree, Lee, Ciaran M., Stamou, Panagiota, Skowyra, Agnieszka, Bustamante-Garrido, Milan, Regazzoni, Karine, Crawford, Nyree, McDade, Simon S., Longley, Daniel B., Aza-Blanc, Pedro, Shanahan, Fergus, Zulquernain, Syed A., McCarthy, Jane, Melgar, Silvia, McRae, Bradford L., Nally, Ken
Published in Cell death & disease (23.09.2021)
Published in Cell death & disease (23.09.2021)
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Near infrared readouts offer sensitive and rapid assessments of intestinal permeability and disease severity in inflammatory bowel disease models
Zhang, Liang, Wallace, Craig D., Erickson, Jamie E., Nelson, Christine M., Gaudette, Stephanie M., Pohl, Calvin S., Karsen, Samuel D., Simler, Gricelda H., Peng, Ruoqi, Stedman, Christopher A., Laroux, F. Stephen, Wurbel, Marc A., Kamath, Rajesh V., McRae, Bradford L., Schwartz Sterman, Annette J., Mitra, Soumya
Published in Scientific reports (13.03.2020)
Published in Scientific reports (13.03.2020)
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CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches
Argiriadi, Maria A, Benatuil, Lorenzo, Dubrovska, Ievgeniia, Egan, David A, Gao, Lei, Greischar, Amy, Hardman, Jennifer, Harlan, John, Iyer, Ramesh B, Judge, Russell A, Lake, Marc, Perron, Denise C, Sadhukhan, Ramkrishna, Sielaff, Bernhard, Sousa, Silvino, Wang, Rui, McRae, Bradford L
Published in BMC molecular and cell biology (05.08.2019)
Published in BMC molecular and cell biology (05.08.2019)
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Treatment with a CD40 Antagonist Antibody Reverses Severe Proteinuria and Loss of Saliva Production and Restores Glomerular Morphology in Murine Systemic Lupus Erythematosus
Perper, Stuart J, Westmoreland, Susan V, Karman, Jozsef, Twomey, Rachel, Seagal, Jane, Wang, Rui, McRae, Bradford L, Clarke, Stephen H
Published in The Journal of immunology (1950) (01.07.2019)
Published in The Journal of immunology (1950) (01.07.2019)
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Distinct spatiotemporal pattern of CNS lesions revealed by USPIO-enhanced MRI in MOG-induced EAE rats implicates the involvement of spino-olivocerebellar pathways
Chin, Chih-Liang, Pai, Madhavi, Bousquet, Peter F, Schwartz, Annette J, O'Connor, Elizabeth M, Nelson, Christine M, Hradil, Vincent P, Cox, Bryan F, McRae, Bradford L, Fox, Gerard B
Published in Journal of neuroimmunology (25.06.2009)
Published in Journal of neuroimmunology (25.06.2009)
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DNA sensor-associated type I interferon signaling is increased in ulcerative colitis and induces JAK-dependent inflammatory cell death in colonic organoids
Flood, Peter, Fanning, Aine, Woznicki, Jerzy A, Crowley, Tadhg, Christopher, Andrea, Vaccaro, Alessandra, Houston, Aileen, McSweeney, Sheila, Ross, Sarah, Hogan, Aileen, Brint, Elizabeth, Skowyra, Agnieszka, Bustamante, Milan, Ambrose, Monica, Moloney, Gerard, MacSharry, John, Hammarström, Marie-Louise, Hurley, Margot, Fitzgibbons, Christine, Quigley, Eamonn M M, Shanahan, Fergus, Zulquernain, Syed A, McCarthy, Jane, Dodson, G Steven, Dabbagh, Karim, McRae, Bradford L, Melgar, Silvia, Nally, Ken
Published in American journal of physiology: Gastrointestinal and liver physiology (01.11.2022)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.11.2022)
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Epithelial dysfunction is prevented by IL-22 treatment in a Citrobacter rodentium-induced colitis model that shares similarities with inflammatory bowel disease
Zhu, Qifan, Korenfeld, Daniel, Suarez-Fueyo, Abel, Graham, Sean, Jin, Liang, Punit, Shivesh, Duffy, Rachael, Puri, Munish, Caruso, Andrew, Hu, Chenqi, Tian, Yu, McRae, Bradford L., Kamath, Raj, Phillips, Lucy, Schwartz-Sterman, Annette J., Westmoreland, Susan, Cao, Xiaohong, Levesque, Marc C., Bi, Yingtao, Paez-Cortez, Jesus, Goenka, Radhika
Published in Mucosal immunology (01.06.2022)
Published in Mucosal immunology (01.06.2022)
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Anti–Tumor Necrosis Factor With a Glyco-Engineered Fc-Region Has Increased Efficacy in Mice With Colitis
Bloemendaal, Felicia M., Levin, Alon D., Wildenberg, Manon E., Koelink, Pim J., McRae, Bradford L., Salfeld, Jochen, Lum, Jenifer, van der Neut Kolfschoten, Marijn, Claassens, Jill W., Visser, Remco, Bentlage, Arthur, D’Haens, Geert R.A.M., Verbeek, J. Sjef, Vidarsson, Gestur, van den Brink, Gijs R.
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2017)
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Fc Receptor-mediated Effector Function Contributes to the Therapeutic Response of Anti-TNF Monoclonal Antibodies in a Mouse Model of Inflammatory Bowel Disease
McRae, Bradford L., Levin, Alon D., Wildenberg, Manon E., Koelink, Pim J., Bousquet, Peter, Mikaelian, Igor, Sterman, Annette Schwartz, Bryant, Shaughn, D’Haens, Geert, Kamath, Rajesh, Salfeld, Jochen, van den Brink, Gijs R
Published in Journal of Crohn's and colitis (01.01.2016)
Published in Journal of Crohn's and colitis (01.01.2016)
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Anti-Inflammatory Effects of FTY720 Do Not Prevent Neuronal Cell Loss in a Rat Model of Optic Neuritis
Rau, Christian R, Hein, Katharina, Sättler, Muriel B, Kretzschmar, Benedikt, Hillgruber, Carina, McRae, Bradford L, Diem, Ricarda, Bähr, Mathias
Published in The American journal of pathology (01.04.2011)
Published in The American journal of pathology (01.04.2011)
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40 ANTI-CD40 ANTIBODIES AND USES THEREOF
ARGIRIADI MARIA A, HSIEH CHUNG MING, WANG RUI, EGAN DAVID A, JUDGE RUSSELL A, MCRAE BRADFORD L, HARLAN JOHN E, KINGSBURY GILLIAN A, BENATUIL LORENZO
Year of Publication 30.04.2024
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Year of Publication 30.04.2024
Patent
항-CD40 항체 및 그의 용도
ARGIRIADI MARIA A, HSIEH CHUNG MING, MCRAE BRADFORD L, BENATUIL LORENZO
Year of Publication 30.01.2018
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Year of Publication 30.01.2018
Patent
Suppression of CD4 + T cell activation by a novel inhibitor of Src family kinases
McRae, Bradford L., Wallace, Craig, Dixon, Kathleen Fitzgerald, Roux, Alyson, Mohan, Sukumari, Jia, Yong, Presky, David H., Tracey, Daniel E., Hirst, Gavin C.
Published in International immunopharmacology (01.04.2005)
Published in International immunopharmacology (01.04.2005)
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Induction of active and adoptive relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein
McRae, Bradford L., Kennedy, Mary K., Tan, Lit-Jen, Dal Canto, Mauro C., Picha, Kathleen S., Miller, Stephen D.
Published in Journal of neuroimmunology (01.06.1992)
Published in Journal of neuroimmunology (01.06.1992)
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631 - BCL2 Regulates Differentiation of Intestinal Fibroblasts
Weder, Bruce, Mamie, Céline, Rogler, Gerhard, Clarke, Stephen, McRae, Bradford L., Ruiz-Castro, Pedro A., Hausmann, Martin
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
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158 – Leveraging Human Intestinal Organoids to Advance Il-22-Based Therapies for Ulcerative Colitis
Patnaude, Lori, Mayo, Martha, Mario, Regina, Wilson, Sarah, Peso, Paul, Knight, Heather, Legendre, Kristen, Karsen, Sam, Yang, Yingli, Melim, Terry, Creamer, Kelly, Pivorunas, Valerie L., Westmoreland, Susan, Dunstan, Robert, Sterman, Annette Schwartz, Slavin, Anthony, Kamath, Rajesh, McRae, Bradford L., Terrillon, Sonia
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
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Su2050 – Near Infrared (NIR) Fluorescence Readouts of Intestinal Permeability and Disease Severity in Murine IBD Models
Mitra, Soumya, Zhang, Liang, Wallace, Craig, Erickson, Jamie, Nelson, Christine, Gaudette, Stephanie, Karsen, Sam, Stedman, Christopher, Laroux, Stephen, Simler, Gricelda, Peng, Ruoqi, Wurbel, Marc-Andre, Kamath, Rajesh, McRae, Bradford L., Slavin, Anthony, Sterman, Annette Schwartz
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
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Tu1736 - Biomarkers for IL-22 Based Therapies
Pivorunas, Valerie L., Patnaude, Lori, Bousquet, Peter, Lynch, Grace, Hart, Michelle, Wallace, Craig, Wong, Laura, Creamer, Kelly, Tian, Yu, Cui, Baoliang, Cuff, Carolyn, Sterman, Annette Schwartz, McRae, Bradford L.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
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