Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs
Han, Seong Kyu, McNulty, Michelle T., Benway, Christopher J., Wen, Pei, Greenberg, Anya, Onuchic-Whitford, Ana C., Jang, Dongkeun, Flannick, Jason, Burtt, Noël P., Wilson, Parker C., Humphreys, Benjamin D., Wen, Xiaoquan, Han, Zhe, Lee, Dongwon, Sampson, Matthew G.
Published in Nature communications (19.04.2023)
Published in Nature communications (19.04.2023)
Get full text
Journal Article
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney
Eales, James M., Jiang, Xiao, Xu, Xiaoguang, Saluja, Sushant, Akbarov, Artur, Cano-Gamez, Eddie, McNulty, Michelle T., Finan, Christopher, Guo, Hui, Wystrychowski, Wojciech, Szulinska, Monika, Thomas, Huw B., Pramanik, Sanjeev, Chopade, Sandesh, Prestes, Priscilla R., Wise, Ingrid, Evangelou, Evangelos, Salehi, Mahan, Shakanti, Yusif, Ekholm, Mikael, Denniff, Matthew, Nazgiewicz, Alicja, Eichinger, Felix, Godfrey, Bradley, Antczak, Andrzej, Glyda, Maciej, Król, Robert, Eyre, Stephen, Brown, Jason, Berzuini, Carlo, Bowes, John, Caulfield, Mark, Zukowska-Szczechowska, Ewa, Zywiec, Joanna, Bogdanski, Pawel, Kretzler, Matthias, Woolf, Adrian S., Talavera, David, Keavney, Bernard, Maffia, Pasquale, Guzik, Tomasz J., O’Keefe, Raymond T., Trynka, Gosia, Samani, Nilesh J., Hingorani, Aroon, Sampson, Matthew G., Morris, Andrew P., Charchar, Fadi J., Tomaszewski, Maciej
Published in Nature genetics (01.05.2021)
Published in Nature genetics (01.05.2021)
Get full text
Journal Article
Recessive variants in the intergenic NOS1AP-C1orf226 locus cause monogenic kidney disease responsive to anti-proteinuric treatment
Buerger, Florian, Salmanullah, Daanya, Liang, Lorrin, Gauntner, Victoria, Krueger, Kavita, Qi, Maggie, Sharma, Vineeta, Rubin, Alexander, Ball, David, Lemberg, Katharina, Saida, Ken, Merz, Lea Maria, Sever, Sanja, Issac, Biju, Sun, Liang, Guerrero-Castillo, Sergio, Gomez, Alexis C, McNulty, Michelle T, Sampson, Matthew G, Al-Hamed, Mohamed H, Saleh, Mohammed M, Shalaby, Mohamed, Kari, Jameela, Fawcett, James P, Hildebrandt, Friedhelm, Majmundar, Amar J
Published in medRxiv : the preprint server for health sciences (21.03.2024)
Published in medRxiv : the preprint server for health sciences (21.03.2024)
Get more information
Journal Article
An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome
Gillies, Christopher E., Putler, Rosemary, Menon, Rajasree, Otto, Edgar, Yasutake, Kalyn, Nair, Viji, Hoover, Paul, Lieb, David, Li, Shuqiang, Eddy, Sean, Fermin, Damian, McNulty, Michelle T., Sedor, John, Dell, Katherine, Schachere, Marleen, Lemley, Kevin, Whitted, Lauren, Srivastava, Tarak, Haney, Connie, Sethna, Christine, Grammatikopoulos, Kalliopi, Appel, Gerald, Toledo, Michael, Greenbaum, Laurence, Wang, Chia-shi, Lee, Brian, Adler, Sharon, Nast, Cynthia, LaPage, Janine, Athavale, Ambarish, Neu, Alicia, Boynton, Sara, Fervenza, Fernando, Hogan, Marie, Lieske, John C., Chernitskiy, Vladimir, Kaskel, Frederick, Kumar, Neelja, Flynn, Patricia, Kopp, Jeffrey, Castro-Rubio, Eveleyn, Blake, Jodi, Trachtman, Howard, Zhdanova, Olga, Modersitzki, Frank, Vento, Suzanne, Lafayette, Richard, Mehta, Kshama, Gadegbeku, Crystal, Johnstone, Duncan, Cattran, Daniel, Hladunewich, Michelle, Reich, Heather, Ling, Paul, Romano, Martin, Fornoni, Alessia, Barisoni, Laura, Bidot, Carlos, Kretzler, Matthias, Gipson, Debbie, Williams, Amanda, Pitter, Renee, Nachman, Patrick, Grubbs, Sandra, Froment, Anne, Holzman, Lawrence, Meyers, Kevin, Kallem, Krishna, Cerecino, Fumei, Sambandam, Kamal, Brown, Elizabeth, Johnson, Natalie, Jefferson, Ashley, Hingorani, Sangeeta, Tuttle, Kathleen, Curtin, Laura, Dismuke, S., Cooper, Ann, Freedman, Barry, Lin, Jen Jar, Gray, Stefanie, Barisoni, Larua, Gillespie, Brenda, Mariani, Laura, Sampson, Matthew G., Song, Peter, Troost, Johnathan, Zee, Jarcy, Herreshoff, Emily, Kincaid, Colleen, Lienczewski, Chrysta, Mainieri, Tina, Abbott, Kevin, Roy, Cindy, Urv, Tiina, Brooks, John, Hacohen, Nir, Kretzler, Matthias, Wen, Xiaoquan, Sampson, Matthew G.
Published in American journal of human genetics (02.08.2018)
Published in American journal of human genetics (02.08.2018)
Get full text
Journal Article
Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome
Jia, Xiaoyuan, Yamamura, Tomohiko, McNulty, Michelle T., Nagano, China, Hitomi, Yuki, Aiba, Yoshihiro, Khor, Seik-Soon, Ueno, Kazuko, Nagasaki, Masao, Hamada, Riku, Okamoto, Takayuki, Fujimaru, Rika, Tanaka, Ryojiro, Shima, Yuko, Araki, Yoshinori, Nagaoka, Yoshinobu, Okamoto, Takayuki, Sato, Yasuyuki, Ueno, Michihiko, Toita, Nariaki, Kobayashi, Norio, Kumagai, Naonori, Kudo, Hiroki, Okada, Mari, Hatai, Yoshiho, Udagawa, Tomohiro, Motoyoshi, Yaeko, Sato, Mai, Harita, Yutaka, Kobayashi, Anna, Ohwada, Yoko, Hataya, Hiroshi, Hamada, Riku, Terano, Chikako, Machida, Hiroyuki, Inaba, Aya, Matsuyama, Takeshi, Shimizu, Masaki, Mori, Yukiko, Matsuoka, Daisuke, Noda, Shunsuke, Kitahara, Masashi, Fujita, Naoya, Iijima, Kazumoto, Ishimori, Shingo, Takeshima, Yasuhiro, Fujimaru, Rika, Ueda, Hiroaki, Ashida, Akira, Fujieda, Mikiya, Iwaki, Takuma, Kaku, Yoshitsugu, Nishimura, Manao, Kuroki, Rie, Ohtsuka, Yasufumi, Nishimura, Shinji, Sato, Tadashi, Zaitsu, Ayuko, Kang, Hee Gyung, Han, Kyoung Hee, Yang, Eun Mi, Cheong, Hae Il, Kim, Ji Hyun, Park, Peong Gang, Han, Kyoung Hee, Lane, Brandon, Solarin, Adaobi, Quiroga, Alejandro, Moudgil, Asha, Chavers, Blanche, Gipson, Deb, Chand, Deepa, Weaver, Donald Jack, Abraham, Elizabeth, Greenbaum, Larry, Kallash, Mahmoud, Gbadegesin, Rasheed, Massengill, Susan, Hunley, Tray, Cai, Yi, Kari, Jameela A., Benoist, Gregoire, Bucher, Julie, Chace, Anne, Chalvon, Arnaud, Daoud, Patrick, Elias, Ossam, Gajdos, Vincent, Galerne, Aurélien, Sanchez, Lydie Joly, Laoudi, Yacine, Muller, Stephanie, Nathanson, Sylvie, Pellegrino, Béatrice, Roudault, Véronica, Rouget, Sébastien, Saf, Marc, Debiec, Hanna, Ishikura, Kenji, Nozu, Kandai
Published in Kidney international (01.11.2020)
Published in Kidney international (01.11.2020)
Get full text
Journal Article
Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome
Barry, Alexandra, McNulty, Michelle T., Jia, Xiaoyuan, Gupta, Yask, Debiec, Hanna, Luo, Yang, Nagano, China, Horinouchi, Tomoko, Jung, Seulgi, Colucci, Manuela, Ahram, Dina F., Mitrotti, Adele, Sinha, Aditi, Teeninga, Nynke, Jin, Gina, Shril, Shirlee, Caridi, Gianluca, Bodria, Monica, Lim, Tze Y., Westland, Rik, Zanoni, Francesca, Marasa, Maddalena, Turudic, Daniel, Giordano, Mario, Gesualdo, Loreto, Magistroni, Riccardo, Pisani, Isabella, Fiaccadori, Enrico, Reiterova, Jana, Maringhini, Silvio, Morello, William, Montini, Giovanni, Weng, Patricia L., Scolari, Francesco, Saraga, Marijan, Tasic, Velibor, Santoro, Domenica, van Wijk, Joanna A. E., Milošević, Danko, Kawai, Yosuke, Kiryluk, Krzysztof, Pollak, Martin R., Gharavi, Ali, Lin, Fangmin, Simœs e Silva, Ana Cristina, Loos, Ruth J. F., Kenny, Eimear E., Schreuder, Michiel F., Zurowska, Aleksandra, Dossier, Claire, Ariceta, Gema, Drozynska-Duklas, Magdalena, Hogan, Julien, Jankauskiene, Augustina, Hildebrandt, Friedhelm, Prikhodina, Larisa, Song, Kyuyoung, Bagga, Arvind, Cheong, Hae, Ghiggeri, Gian Marco, Vachvanichsanong, Prayong, Nozu, Kandai, Lee, Dongwon, Vivarelli, Marina, Raychaudhuri, Soumya, Tokunaga, Katsushi, Sanna-Cherchi, Simone, Ronco, Pierre, Iijima, Kazumoto, Sampson, Matthew G.
Published in Nature communications (29.04.2023)
Published in Nature communications (29.04.2023)
Get full text
Journal Article
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease
Gupta, Yask, Friedman, David J., McNulty, Michelle T., Khan, Atlas, Lane, Brandon, Wang, Chen, Ke, Juntao, Jin, Gina, Wooden, Benjamin, Knob, Andrea L., Lim, Tze Y., Appel, Gerald B., Huggins, Kinsie, Liu, Lili, Mitrotti, Adele, Stangl, Megan C., Bomback, Andrew, Westland, Rik, Bodria, Monica, Marasa, Maddalena, Shang, Ning, Cohen, David J., Crew, Russell J., Morello, William, Canetta, Pietro, Radhakrishnan, Jai, Martino, Jeremiah, Liu, Qingxue, Chung, Wendy K., Espinoza, Angelica, Luo, Yuan, Wei, Wei-Qi, Feng, Qiping, Weng, Chunhua, Fang, Yilu, Kullo, Iftikhar J., Naderian, Mohammadreza, Limdi, Nita, Irvin, Marguerite R., Tiwari, Hemant, Mohan, Sumit, Rao, Maya, Dube, Geoffrey K., Chaudhary, Ninad S., Gutiérrez, Orlando M., Judd, Suzanne E., Cushman, Mary, Lange, Leslie A., Lange, Ethan M., Bivona, Daniel L., Verbitsky, Miguel, Winkler, Cheryl A., Kopp, Jeffrey B., Santoriello, Dominick, Batal, Ibrahim, Pinheiro, Sérgio Veloso Brant, Oliveira, Eduardo Araújo, Simoes e Silva, Ana Cristina, Pisani, Isabella, Fiaccadori, Enrico, Lin, Fangming, Gesualdo, Loreto, Amoroso, Antonio, Ghiggeri, Gian Marco, D’Agati, Vivette D., Magistroni, Riccardo, Kenny, Eimear E., Loos, Ruth J. F., Montini, Giovanni, Hildebrandt, Friedhelm, Paul, Dirk S., Petrovski, Slavé, Goldstein, David B., Kretzler, Matthias, Gbadegesin, Rasheed, Gharavi, Ali G., Kiryluk, Krzysztof, Sampson, Matthew G., Pollak, Martin R., Sanna-Cherchi, Simone
Published in Nature communications (30.11.2023)
Published in Nature communications (30.11.2023)
Get full text
Journal Article
A glomerular transcriptomic landscape of apolipoprotein L1 in Black patients with focal segmental glomerulosclerosis
McNulty, Michelle T., Fermin, Damian, Eichinger, Felix, Jang, Dongkeun, Kretzler, Matthias, Burtt, Noël P., Pollak, Martin R., Flannick, Jason, Weins, Astrid, Friedman, David J., Dell, K., Sedor, J., Schachere, M., Negrey, J., Lemley, K., Silesky, B., Srivastava, T., Garrett, A., Sethna, C., Canetta, P., Pradhan, A., Greenbaum, L., Wang, C., Kang, C., Adler, S., LaPage, J., Athavale, A., Itteera, M., Atkinson, M., Dell, T., Hogan, M., Lieske, J., Chernitskiy, V., Kaskel, F., Ross, M., Flynn, P., Kopp, J., Blake, J., Trachtman, H., Zhdanova, O., Modersitzki, F., Vento, S., Lafayette, R., Mehta, K., Quinn-Boyle, S., Hladunewich, M., Reich, H., Ling, P., Romano, M., Fornoni, A., Bidot, C., Kretzler, M., Gipson, D., Williams, A., Klida, C., Derebail, V., Gibson, K., Cole, E., Ormond-Foster, J., Holzman, L., Kallem, K., Swenson, A., Sambandam, K., Wang, Z., Rogers, M., Jefferson, A., Hingorani, S., Bray, M., Pao, E., Cooper, A., Lin, J.J., Baker, Stefanie, Barisoni, L., Bixler, J., Desmond, H., Eddy, S., Fermin, D., Gillespie, B., Larkina, M., Li, S., Lienczewski, C.C., Liu, J., Mainieri, T., Mariani, L., Sampson, M., Smith, A., Zee, J., Avila-Casado, Carmen, Bagnasco, Serena, Gaut, Joseph, Hodgin, Jeff, Lemley, Kevin, Mariani, Laura, Rosenberg, Avi, Royal, Virginie, Thomas, David, Zee, Jarcy, Barisoni, Laura, Nast, Cynthia, Sampson, Matthew G.
Published in Kidney international (01.07.2022)
Published in Kidney international (01.07.2022)
Get full text
Journal Article