Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment
Venkatraman, Ganesh, Benesch, Matthew G K, Tang, Xiaoyun, Dewald, Jay, McMullen, Todd P W, Brindley, David N
Published in The FASEB journal (01.03.2015)
Published in The FASEB journal (01.03.2015)
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Tumor-induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression
Benesch, Matthew G K, Tang, Xiaoyun, Dewald, Jay, Dong, Wei-Feng, Mackey, John R, Hemmings, Denise G, McMullen, Todd P W, Brindley, David N
Published in The FASEB journal (01.09.2015)
Published in The FASEB journal (01.09.2015)
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Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance
Bekele, Raie T, Venkatraman, Ganesh, Liu, Rong-Zong, Tang, Xiaoyun, Mi, Si, Benesch, Matthew G K, Mackey, John R, Godbout, Roseline, Curtis, Jonathan M, McMullen, Todd P W, Brindley, David N
Published in Scientific reports (17.02.2016)
Published in Scientific reports (17.02.2016)
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Implications for breast cancer treatment from increased autotaxin production in adipose tissue after radiotherapy
Meng, Guanmin, Tang, Xiaoyun, Yang, Zelei, Benesch, Matthew G K, Marshall, Alison, Murray, David, Hemmings, Denise G, Wuest, Frank, McMullen, Todd P W, Brindley, David N
Published in The FASEB journal (01.09.2017)
Published in The FASEB journal (01.09.2017)
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PDGFRα Enhanced Infection of Breast Cancer Cells with Human Cytomegalovirus but Infection of Fibroblasts Increased Prometastatic Inflammation Involving Lysophosphatidate Signaling
Yang, Zelei, Tang, Xiaoyun, McMullen, Todd P. W., Brindley, David N., Hemmings, Denise G.
Published in International journal of molecular sciences (10.09.2021)
Published in International journal of molecular sciences (10.09.2021)
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Dexamethasone decreases the autotaxin-lysophosphatidate-inflammatory axis in adipose tissue: implications for the metabolic syndrome and breast cancer
Meng, Guanmin, Tang, Xiaoyun, Yang, Zelei, Zhao, YuanYuan, Curtis, Jonathan M, McMullen, Todd P W, Brindley, David N
Published in The FASEB journal (01.02.2019)
Published in The FASEB journal (01.02.2019)
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Positron Emission Tomography Imaging of Autotaxin in Thyroid and Breast Cancer Models Using [18F]PRIMATX
Litchfield, Marcus, Wuest, Melinda, Glubrecht, Daryl, Briard, Emmanuelle, Auberson, Yves P, McMullen, Todd P. W, Brindley, David N, Wuest, Frank
Published in Molecular pharmaceutics (06.09.2021)
Published in Molecular pharmaceutics (06.09.2021)
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Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice
Benesch, Matthew G K, Tang, Xiaoyun, Maeda, Tatsuo, Ohhata, Akira, Zhao, Yuan Y, Kok, Bernard P C, Dewald, Jay, Hitt, Mary, Curtis, Jonathan M, McMullen, Todd P W, Brindley, David N
Published in The FASEB journal (01.06.2014)
Published in The FASEB journal (01.06.2014)
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Gene expression profile of epithelial-mesenchymal transition mediators in papillary thyroid cancer
Lopez-Campistrous, Ana, Adewuyi, Esther Ekpe, Williams, David C., McMullen, Todd P. W.
Published in Endocrine (01.05.2021)
Published in Endocrine (01.05.2021)
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Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer
Benesch, Matthew G K, Ko, Yi M, Tang, Xiaoyun, Dewald, Jay, Lopez-Campistrous, Ana, Zhao, Yuan Y, Lai, Raymond, Curtis, Jonathan M, Brindley, David N, McMullen, Todd P W
Published in Endocrine-related cancer (01.08.2015)
Published in Endocrine-related cancer (01.08.2015)
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Human Cytomegalovirus Seropositivity and Viral DNA in Breast Tumors Are Associated with Poor Patient Prognosis
Yang, Zelei, Tang, Xiaoyun, Hasing, Maria Eloisa, Pang, Xiaoli, Ghosh, Sunita, McMullen, Todd P W, Brindley, David N, Hemmings, Denise G
Published in Cancers (23.02.2022)
Published in Cancers (23.02.2022)
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Repeated Fractions of X-Radiation to the Breast Fat Pads of Mice Augment Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle
Meng, Guanmin, Wuest, Melinda, Tang, Xiaoyun, Dufour, Jennifer, Zhao, YuanYuan, Curtis, Jonathan M, McMullen, Todd P W, Murray, David, Wuest, Frank, Brindley, David N
Published in Cancers (19.11.2019)
Published in Cancers (19.11.2019)
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Molecular imaging of platelet-derived growth factor receptor-alpha (PDGFRα) in papillary thyroid cancer using immuno-PET
Wagner, Michael, Wuest, Melinda, Hamann, Ingrit, Lopez-Campistrous, Ana, McMullen, Todd P.W., Wuest, Frank
Published in Nuclear medicine and biology (01.03.2018)
Published in Nuclear medicine and biology (01.03.2018)
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Normal human adipose tissue functions and differentiation in patients with biallelic LPIN1 inactivating mutations
Pelosi, Michele, Testet, Eric, Le Lay, Soazig, Dugail, Isabelle, Tang, Xiaoyun, Mabilleau, Guillaume, Hamel, Yamina, Madrange, Marine, Blanc, Thomas, Odent, Thierry, McMullen, Todd P.W., Alfò, Marco, Brindley, David N., de Lonlay, Pascale
Published in Journal of lipid research (01.12.2017)
Published in Journal of lipid research (01.12.2017)
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The Wnt/ β -catenin pathway drives increased cyclin D1 levels in lymph node metastasis in papillary thyroid cancer
Zhang, Jingdong, MD, Gill, Anthony J.M., MD, Issacs, Joseph D., MD, Atmore, Bryn, MD, Johns, Amber, MD, Delbridge, Leigh W., MD, Lai, Raymond, MD, PhD, McMullen, Todd P.W., MD, PhD
Published in Human pathology (01.07.2012)
Published in Human pathology (01.07.2012)
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Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice[S]
Tang, Xiaoyun, Benesch, Matthew G.K., Dewald, Jay, Zhao, Yuan Y., Patwardhan, Neeraj, Santos, Webster L., Curtis, Jonathan M., McMullen, Todd P.W., Brindley, David N.
Published in Journal of lipid research (01.11.2014)
Published in Journal of lipid research (01.11.2014)
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Dexamethasone Attenuates X-Ray-Induced Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle in Breast Tissue and Subsequent Breast Fibrosis
Meng, Guanmin, Wuest, Melinda, Tang, Xiaoyun, Dufour, Jennifer, McMullen, Todd P W, Wuest, Frank, Murray, David, Brindley, David N
Published in Cancers (18.04.2020)
Published in Cancers (18.04.2020)
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