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Published in Nature materials (01.05.2021)
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Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles
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Published in Nature communications (16.09.2021)
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Lipophilic nanocrystal prodrug-release defines the extended pharmacokinetic profiles of a year-long cabotegravir
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Published in Nature communications (08.06.2021)
Published in Nature communications (08.06.2021)
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Neurotheranostics as personalized medicines
Kevadiya, Bhavesh D., Ottemann, Brendan M., Thomas, Midhun Ben, Mukadam, Insiya, Nigam, Saumya, McMillan, JoEllyn, Gorantla, Santhi, Bronich, Tatiana K., Edagwa, Benson, Gendelman, Howard E.
Published in Advanced drug delivery reviews (01.08.2019)
Published in Advanced drug delivery reviews (01.08.2019)
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Bench-to-bedside translation of magnetic nanoparticles
Singh, Dhirender, McMillan, JoEllyn M, Kabanov, Alexander V, Sokolsky-Papkov, Marina, Gendelman, Howard E
Published in Nanomedicine (London, England) (01.04.2014)
Published in Nanomedicine (London, England) (01.04.2014)
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Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation
Deodhar, Suyash, Sillman, Brady, Bade, Aditya N, Avedissian, Sean N, Podany, Anthony T, McMillan, JoEllyn M, Gautam, Nagsen, Hanson, Brandon, Dyavar Shetty, Bhagya L, Szlachetka, Adam, Johnston, Morgan, Thurman, Michellie, Munt, Daniel J, Dash, Alekha K, Markovic, Milica, Dahan, Arik, Alnouti, Yazen, Yazdi, Alborz, Kevadiya, Bhavesh D, Byrareddy, Siddappa N, Cohen, Samuel M, Edagwa, Benson, Gendelman, Howard E
Published in Nature communications (09.06.2022)
Published in Nature communications (09.06.2022)
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Macrophage Delivery of Nanoformulated Antiretroviral Drug to the Brain in a Murine Model of NeuroAIDS
Dou, Huanyu, Grotepas, Cassi B, McMillan, JoEllyn M, Destache, Christopher J, Chaubal, Mahesh, Werling, Jane, Kipp, James, Rabinow, Barrett, Gendelman, Howard E
Published in The Journal of immunology (1950) (01.07.2009)
Published in The Journal of immunology (1950) (01.07.2009)
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A year-long extended release nanoformulated cabotegravir prodrug
Kulkarni, Tanmay A, Bade, Aditya N, Sillman, Brady, Shetty, Bhagya Laxmi Dyavar, Wojtkiewicz, Melinda S, Gautam, Nagsen, Hilaire, James R, Sravanam, Sruthi, Szlachetka, Adam, Lamberty, Benjamin G, Morsey, Brenda M, Fox, Howard S, Alnouti, Yazen, McMillan, JoEllyn M, Mosley, R Lee, Meza, Jane, Domanico, Paul L, Yue, Tai-Yuen, Moore, Gary, Edagwa, Benson J, Gendelman, Howard E
Published in Nature materials (01.08.2020)
Published in Nature materials (01.08.2020)
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Creation of a long-acting nanoformulated dolutegravir
Sillman, Brady, Bade, Aditya N, Dash, Prasanta K, Bhargavan, Biju, Kocher, Ted, Mathews, Saumi, Su, Hang, Kanmogne, Georgette D, Poluektova, Larisa Y, Gorantla, Santhi, McMillan, JoEllyn, Gautam, Nagsen, Alnouti, Yazen, Edagwa, Benson, Gendelman, Howard E
Published in Nature communications (06.02.2018)
Published in Nature communications (06.02.2018)
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Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment
Bade, Aditya N., McMillan, JoEllyn M., Liu, Yutong, Edagwa, Benson J., Gendelman, Howard E.
Published in Molecular neurobiology (01.11.2021)
Published in Molecular neurobiology (01.11.2021)
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Bioimaging predictors of rilpivirine biodistribution and antiretroviral activities
Ottemann, Brendan M., Helmink, Austin J., Zhang, Wenting, Mukadam, Insiya, Woldstad, Christopher, Hilaire, James R., Liu, Yutong, McMillan, JoEllyn M., Edagwa, Benson J., Mosley, R. Lee, Garrison, Jered C., Kevadiya, Bhavesh D., Gendelman, Howard E.
Published in Biomaterials (01.12.2018)
Published in Biomaterials (01.12.2018)
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EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment
Gu, Chao-Jiang, Borjabad, Alejandra, Hadas, Eran, Kelschenbach, Jennifer, Kim, Boe-Hyun, Chao, Wei, Arancio, Ottavio, Suh, Jin, Polsky, Bruce, McMillan, JoEllyn, Edagwa, Benson, Gendelman, Howard E, Potash, Mary Jane, Volsky, David J
Published in PLoS pathogens (01.06.2018)
Published in PLoS pathogens (01.06.2018)
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Creation of a long-acting rilpivirine prodrug nanoformulation
Hilaire, James R., Bade, Aditya N., Sillman, Brady, Gautam, Nagsen, Herskovitz, Jonathan, Dyavar Shetty, Bhagya Laxmi, Wojtkiewicz, Melinda S., Szlachetka, Adam, Lamberty, Benjamin G., Sravanam, Sruthi, Fox, Howard S., Alnouti, Yazen, Dash, Prasanta K., McMillan, JoEllyn M., Edagwa, Benson J., Gendelman, Howard E.
Published in Journal of controlled release (01.10.2019)
Published in Journal of controlled release (01.10.2019)
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Efavirenz, atazanavir, and ritonavir disrupt sarcoplasmic reticulum Ca2+ homeostasis in skeletal muscles
Alomar, Fadhel A., Tian, Chengju, Dash, Prasanta K., McMillan, JoEllyn M., Gendelman, Howard E., Gorantla, Santhi, Bidasee, Keshore R.
Published in Antiviral research (01.03.2021)
Published in Antiviral research (01.03.2021)
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Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy
Martinez-Skinner, Andrea L, Araínga, Mariluz A, Puligujja, Pavan, Palandri, Diana L, Baldridge, Hannah M, Edagwa, Benson J, McMillan, JoEllyn M, Mosley, R Lee, Gendelman, Howard E
Published in PloS one (30.12.2015)
Published in PloS one (30.12.2015)
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Development of europium doped core-shell silica cobalt ferrite functionalized nanoparticles for magnetic resonance imaging
Kevadiya, Bhavesh D., Bade, Aditya N., Woldstad, Christopher, Edagwa, Benson J., McMillan, JoEllyn M., Sajja, Balasrinivasa R., Boska, Michael D., Gendelman, Howard E.
Published in Acta biomaterialia (01.02.2017)
Published in Acta biomaterialia (01.02.2017)
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Endosomal trafficking of nanoformulated antiretroviral therapy facilitates drug particle carriage and HIV clearance
Guo, Dongwei, Zhang, Gang, Wysocki, Tadeusz A, Wysocki, Beata J, Gelbard, Harris A, Liu, Xin-Ming, McMillan, JoEllyn M, Gendelman, Howard E
Published in Journal of virology (01.09.2014)
Published in Journal of virology (01.09.2014)
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Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations
Puligujja, Pavan, Balkundi, Shantanu S, Kendrick, Lindsey M, Baldridge, Hannah M, Hilaire, James R, Bade, Aditya N, Dash, Prasanta K, Zhang, Gang, Poluektova, Larisa Y, Gorantla, Santhi, Liu, Xin-Ming, Ying, Tianlei, Feng, Yang, Wang, Yanping, Dimitrov, Dimiter S, McMillan, JoEllyn M, Gendelman, Howard E
Published in Biomaterials (01.02.2015)
Published in Biomaterials (01.02.2015)
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