Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket
Zimmerman, Brandon, Kelly, Brendan, McMillan, Brian J., Seegar, Tom C.M., Dror, Ron O., Kruse, Andrew C., Blacklow, Stephen C.
Published in Cell (03.11.2016)
Published in Cell (03.11.2016)
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Journal Article
Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease
Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A, Chaffin, Mark, Horner, Steven, McMillan, Brian J, Leed, Alison, Weale, Michael E, Spencer, Chris C A, Aguet, François, Segrè, Ayellet V, Ardlie, Kristin G, Khera, Amit V, Kaushik, Virendar K, Natarajan, Pradeep, Kathiresan, Sekar
Published in Nature genetics (01.09.2017)
Published in Nature genetics (01.09.2017)
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Journal Article
Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations
McMillan, Brian J, Zimmerman, Brandon, Egan, Emily D, Lofgren, Michael, Xu, Xiang, Hesser, Anthony, Blacklow, Stephen C
Published in Glycobiology (Oxford) (01.08.2017)
Published in Glycobiology (Oxford) (01.08.2017)
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Journal Article
Aryl hydrocarbon receptor is activated by modified low-density lipoprotein
McMillan, Brian J, Bradfield, Christopher A
Published in Proceedings of the National Academy of Sciences - PNAS (23.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (23.01.2007)
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Journal Article
A Tail of Two Sites: A Bipartite Mechanism for Recognition of Notch Ligands by Mind Bomb E3 Ligases
McMillan, Brian J., Schnute, Björn, Ohlenhard, Nadja, Zimmerman, Brandon, Miles, Laura, Beglova, Natalia, Klein, Thomas, Blacklow, Stephen C.
Published in Molecular cell (05.03.2015)
Published in Molecular cell (05.03.2015)
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Journal Article
Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein
McMillan, Brian J., Tibbe, Christine, Jeon, Hyesung, Drabek, Andrew A., Klein, Thomas, Blacklow, Stephen C.
Published in Cell reports (Cambridge) (02.08.2016)
Published in Cell reports (Cambridge) (02.08.2016)
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Journal Article
Structural Basis for Regulation of ESCRT-III Complexes by Lgd
McMillan, Brian J., Tibbe, Christine, Drabek, Andrew A., Seegar, Tom C.M., Blacklow, Stephen C., Klein, Thomas
Published in Cell reports (Cambridge) (30.05.2017)
Published in Cell reports (Cambridge) (30.05.2017)
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Journal Article
Structure and function of the Mind bomb E3 ligase in the context of Notch signal transduction
Guo, Bingqian, McMillan, Brian J, Blacklow, Stephen C
Published in Current opinion in structural biology (01.12.2016)
Published in Current opinion in structural biology (01.12.2016)
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Journal Article
EDGE: A Centralized Resource for the Comparison, Analysis, and Distribution of Toxicogenomic Information
Hayes, Kevin R, Vollrath, Aaron L, Zastrow, Gina M, McMillan, Brian J, Craven, Mark, Jovanovich, Stevan, Rank, David R, Penn, Sharon, Walisser, Jacqueline A, Reddy, Janardan K, Thomas, Russell S, Bradfield, Christopher A
Published in Molecular pharmacology (01.04.2005)
Published in Molecular pharmacology (01.04.2005)
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Journal Article
Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction
McKinney, David C, McMillan, Brian J, Ranaghan, Matthew J, Moroco, Jamie A, Brousseau, Merissa, Mullin-Bernstein, Zachary, O’Keefe, Meghan, McCarren, Patrick, Mesleh, Michael F, Mulvaney, Kathleen M, Robinson, Foxy, Singh, Ritu, Bajrami, Besnik, Wagner, Florence F, Hilgraf, Robert, Drysdale, Martin J, Campbell, Arthur J, Skepner, Adam, Timm, David E, Porter, Dale, Kaushik, Virendar K, Sellers, William R, Ianari, Alessandra
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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Journal Article
A Tail of Two Sites: A Bipartite Mechanism for Recognition of Notch Ligands by Mind Bomb E3 Ligases
McMillan, Brian J., Schnute, Björn, Ohlenhard, Nadja, Zimmerman, Brandon, Miles, Laura, Beglova, Natalia, Klein, Thomas, Blacklow, Stephen C.
Published in Molecular cell (16.04.2015)
Published in Molecular cell (16.04.2015)
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Journal Article
Structural Basis for Regulation of ESCRT-III Complexes by Lgd
McMillan, Brian J., Tibbe, Christine, Drabek, Andrew A., Seegar, Tom C. M., Blacklow, Stephen C., Klein, Thomas
Published in Cell reports (Cambridge) (01.05.2017)
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Published in Cell reports (Cambridge) (01.05.2017)
Journal Article
Discovery of a first-in-class inhibitor of the PRMT5-substrate adaptor interaction
Mckinney, David C, Mcmillan, Brian J, Ranaghan, Matthew, Moroco, Jamie A, Brousseau, Merissa, Mullin-Bernstein, Zachary, Meghan O’keefe, Mccarren, Patrick, Mesleh, Michael F, Mulvaney, Kathleen M, Singh, Ritu, Bajrami, Besnik, Skepner, Adam, Timm, David E, Porter, Dale, Kaushik, Virendar K, Sellers, William R, Ianari, Alessandra
Published in bioRxiv (03.02.2021)
Published in bioRxiv (03.02.2021)
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