Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors
Anderson, Malcolm, Andrews, David M., Barker, Andy J., Brassington, Claire A., Breed, Jason, Byth, Kate F., Culshaw, Janet D., Finlay, M. Raymond V., Fisher, Eric, McMiken, Helen H.J., Green, Clive P., Heaton, Dave W., Nash, Ian A., Newcombe, Nicholas J., Oakes, Sandra E., Pauptit, Richard A., Roberts, Andrew, Stanway, Judith J., Thomas, Andrew P., Tucker, Julie A., Walker, Mike, Weir, Hazel M.
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Published in Bioorganic & medicinal chemistry (15.10.2008)
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SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors
Heron, Nicola M., Anderson, Malcolm, Blowers, David P., Breed, Jason, Eden, Jonathan M., Green, Stephen, Hill, George B., Johnson, Trevor, Jung, Frederic H., McMiken, Helen H.J., Mortlock, Andrew A., Pannifer, Andrew D., Pauptit, Richard A., Pink, Jennifer, Roberts, Nicola J., Rowsell, Siân
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Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
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Published in eLife (22.08.2019)
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Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode
Blankenfeldt, Wulf, Kerr, Iain D, Giraud, Marie-France, McMiken, Helen J, Leonard, Gordon, Whitfield, Chris, Messner, Paul, Graninger, Michael, Naismith, James H
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Published in Structure (London) (01.06.2002)
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Crystal Structure of Human Thymidine Phosphorylase in Complex with a Small Molecule Inhibitor
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Published in Structure (London) (01.01.2004)
Published in Structure (London) (01.01.2004)
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Variation on a Theme of SDR
Blankenfeldt, Wulf, Kerr, Iain D, Giraud, Marie-France, McMiken, Helen J, Leonard, Gordon, Whitfield, Chris, Messner, Paul, Graninger, Michael, Naismith, James H
Published in Structure (London) (01.06.2002)
Published in Structure (London) (01.06.2002)
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Variation on a Theme of SDR: dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg 2+-Dependent Dimerization Mode
Blankenfeldt, Wulf, Kerr, Iain D, Giraud, Marie-France, McMiken, Helen J, Leonard, Gordon, Whitfield, Chris, Messner, Paul, Graninger, Michael, Naismith, James H
Published in Structure (London) (2002)
Published in Structure (London) (2002)
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Overexpression, purification, crystallization and preliminary structural study of dTDP-6-deoxy-l-lyxo-4-hexulose reductase (RmlD), the fourth enzyme of the dTDP-l-rhamnose synthesis pathway, from Salmonella enterica serovar Typhimurium
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Published in Acta crystallographica. Section D, Biological crystallography. (01.12.1999)
Published in Acta crystallographica. Section D, Biological crystallography. (01.12.1999)
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Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
Vögtle, Timo, Sharma, Sumana, Mori, Jun, Nagy, Zoltan, Semeniak, Daniela, Geer, Mitchell J, Smith, Christopher W, Lane, Jordan, Pollack, Scott, Lassila, Riitta, Jouppila, Annukka, Barr, Alastair J, Ogg, Derek J, Howard, Tina D, Mcmiken, Helen J, Warwicker, Juli, Geh, Catherine, Rowlinson, Rachel, Abbott, W Mark, Schulze, Harald, Wright, Gavin J, Mazharian, Alexandra, Fütterer, Klaus, Sundaresan Rajesh, Douglas, Michael R, Senis, Yotis A
Published in bioRxiv (25.03.2019)
Published in bioRxiv (25.03.2019)
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Paper
SARr and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors
HERON, Nicola M, ANDERSON, Malcolm, MORTLOCK, Andrew A, PANNIFER, Andrew D, PAUPTIT, Richard A, PINK, Jennifer, ROBERTS, Nicola J, ROWSELL, Sian, BLOWERS, David P, BREED, Jason, EDEN, Jonathan M, GREEN, Stephen, HILL, George B, JOHNSON, Trevor, JUNG, Frederic H, MCMIKEN, Helen H. J
Published in Bioorganic & medicinal chemistry letters (2006)
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Published in Bioorganic & medicinal chemistry letters (2006)
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